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Home/Compounds/CAS 1239908-20-3
Formula C20H23BCl2N2O9MW 517.1Research-use catalog entryCOA/SDS by request

Ixazomib citrate

CAS Number: 1239908-20-3

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Loading RDKit molecule structure...
InChIKey: MBOMYENWWXQSNW-AWEZNQCLSA-NC20H23BCl2N2O9 | MW 517.1

Chemical Absolute Identifiers

CAS Number

1239908-20-3

PubChem CID

56844015

Molecular Formula

C20H23BCl2N2O9

Molecular Weight

517.1 g/mol

Exact Mass

516.087366

InChIKey

MBOMYENWWXQSNW-AWEZNQCLSA-N

IUPAC Name

2-[4-(carboxymethyl)-2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolan-4-yl]acetic acid

SMILES String

CC(C)C[C@H](NC(=O)CNC(=O)c1cc(Cl)ccc1Cl)B1OC(=O)C(CC(=O)O)(CC(=O)O)O1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ixazomib citrate (CAS 1239908-20-3) is listed in the Advanced Chemicals portfolio, with molecular formula C20H23BCl2N2O9 and molecular weight 517. 10 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle, boronic-acid-related structure.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Boronic Acids and EstersSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Proteasome Macropain subunit MB1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Proteasome Macropain subunit MB1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 9.03

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Ixazomib citrate

Names & Synonyms

NINLAROIxazomib citrate (Ester)Ixazomib citrate [USAN](R)-2,2'-(2-(1-(2-(2,5-Dichlorobenzamido)acetamido)-3-methylbutyl)-5-oxo-1,3,2-dioxaborolane-4,4-diyl)diacetic acid1,3,2-Dioxaborolane-4,4-diacetic acid, 2-[(1R)-1-[[2-[(2,5-dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-
Show all synonyms
1,3,2-Dioxaborolane-4,4-diacetic acid, 2-((1R)-1-((2-((2,5-dichlorobenzoyl)amino)acetyl)amino)-3-methylbutyl)-5-oxo-2,2'-{2-[(1R)-1-{[N-(2,5-dichlorobenzoyl)glycyl]amino}-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diyl}diacetic acid2-[(1R)-1-[[2-[(2,5-Dichlorobenzoyl)amino]acetyl]amino]-3-methylbutyl]-5-oxo-1,3,2-dioxaborolane-4,4-diacetic acid2-[4-(carboxymethyl)-2-[(1R)-1-{2-[(2,5-dichlorophenyl)formamido]acetamido}-3-methylbutyl]-5-oxo-1,3,2-dioxaborolan-4-yl]acetic acidC20H23BCl2N2O9Lxazomib Citrate2,2'-(2-((1R)-1-((N-(2,5-DICHLOROBENZOYL)GLYCYL)AMINO)-3-METHYLBUTYL)-5-OXO-1,3,2-DIOXABOROLANE-4,4-DIYL)DIACETIC ACIDNinlaro (TN)IXAZOMIB CITRATE [MI]Ixazomib citrate (JAN/USAN)IXAZOMIB CITRATE [JAN]IXAZOMIB CITRATE [WHO-DD]Ixazomib Citrate (MLN-9708)?s4432
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID60924652CHEMBL ID: CHEMBL3545432CHEBI ID: CHEBI:90939UNII: 46CWK97Z3KKEGG ID: D10131NCI THESAURUS CODE: C82653RXCUI: 1723734WIKIDATA ID: Q27162929
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115492Recent advance of small-molecule drugs for clinical treatment of multiple myeloma.PMID 37210838Recent advance of small-molecule drugs for clinical treatment of multiple myeloma.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

IxazomibCAS 1072833-77-2
Bortezomib boronic anhydrideCAS 390800-88-1
2-(3-Chlorobenzyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneCAS 517920-59-1
1-(4-Chlorophenyl)vinylboronic acid, pinacol esterCAS 850567-54-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1072833-77-2IxazomibCAS 1420477-60-6AcalabrutinibCAS 50-35-1ThalidomideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1239908-20-3

What are the key identifiers for Ixazomib citrate (CAS 1239908-20-3)?

Ixazomib citrate is identified by CAS 1239908-20-3, with molecular formula C20H23BCl2N2O9, molecular weight 517.1, InChIKey MBOMYENWWXQSNW-AWEZNQCLSA-N.

Does CAS 1239908-20-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Proteasome Macropain subunit MB1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1239908-20-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ixazomib citrate?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1239908-20-3 available for quotation?

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