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Home/Compounds/CAS 124750-99-8
Formula C22H22ClKN6OMW 461Research-use catalog entryCOA/SDS by request

Losartan Potassium

CAS Number: 124750-99-8

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1 g
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98%
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Loading RDKit molecule structure...
InChIKey: OXCMYAYHXIHQOA-UHFFFAOYSA-NC22H22ClKN6O | MW 461

Chemical Absolute Identifiers

CAS Number

124750-99-8

PubChem CID

11751549

Molecular Formula

C22H22ClKN6O

Molecular Weight

461 g/mol

Exact Mass

460.118069

InChIKey

OXCMYAYHXIHQOA-UHFFFAOYSA-N

IUPAC Name

potassium [2-butyl-5-chloro-3-[[4-[2-(1,2,3-triaza-4-azanidacyclopenta-2,5-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol

SMILES String

CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Losartan Potassium (CAS 124750-99-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C22H22ClKN6O and molecular weight 461. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Type-1 angiotensin II receptor B (Rattus norvegicus) — 4 assays; Type-1 angiotensin II receptor (Homo sapiens) — 2 assays; Fructose-bisphosphate aldolase (Giardia intestinalis) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Type-1 angiotensin II receptor B

Rattus norvegicus · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 8.82

Experimental evidence source: ChEMBL

Type-1 angiotensin II receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.26

Experimental evidence source: ChEMBL

Fructose-bisphosphate aldolase

Giardia intestinalis · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.9

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Losartan Potassium

Names & Synonyms

CozaarLosacarLosaprexLosataTancin
Show all synonyms
Nu-LotanAradoisZaartLosartan monopotassium saltDuP 753DuP753DU PONT-7532-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, monopotassium saltLosatan PotassiumLosortan PotassiumLosartan Potatssium2-Butyl-4-chloro-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-imidazole-5-methanol, Monopotassium SaltPotassium, Losartan
External Identifiers
EC NUMBER: 627-032-3EC NUMBER: 658-044-7DSSTOX SUBSTANCE ID: DTXSID3044209CHEMBL ID: CHEMBL995UNII: 3ST302B24AKEGG ID: D00357NCI THESAURUS CODE: C29165RXCUI: 203160Presartan-50DuP-753
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1093/toxsci/kft176A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.PMID 23956101A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.DOI 10.1016/j.bmc.2007.06.056Losartan and its interaction with copper(II): biological effects.PMID 17651974Losartan and its interaction with copper(II): biological effects.DOI 10.1021/jm0204237Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Losartan carboxylic acidCAS 124750-92-1
IrbesartanCAS 138402-11-6
4'-((2-Butyl-4-oxo-1,3-diazaspiro(4.4)non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrileCAS 138401-24-8
Telmisartan methyl esterCAS 528560-93-2
Azilsartan KamedoxomilCAS 863031-24-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 124750-92-1Losartan carboxylic acidCAS 83857-96-92-Butyl-5-chloro-1H-imidazole-4-carbaldehydeCAS 138402-11-6IrbesartanCAS 139481-59-7CandesartanCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 124750-99-8

What are the key identifiers for Losartan Potassium (CAS 124750-99-8)?

Losartan Potassium is identified by CAS 124750-99-8, with molecular formula C22H22ClKN6O, molecular weight 461, InChIKey OXCMYAYHXIHQOA-UHFFFAOYSA-N.

Does CAS 124750-99-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Type-1 angiotensin II receptor B, Type-1 angiotensin II receptor, Fructose-bisphosphate aldolase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 124750-99-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Losartan Potassium?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 124750-99-8 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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