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Home/Compounds/CAS 129-03-3
Formula C21H21NMW 287.4Research-use catalog entryCOA/SDS by request

Cyproheptadine

CAS Number: 129-03-3

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Available Options

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100 mg
Purity
98+%
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250 mg
Purity
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Loading RDKit molecule structure...
InChIKey: JJCFRYNCJDLXIK-UHFFFAOYSA-NC21H21N | MW 287.4

Chemical Absolute Identifiers

CAS Number

129-03-3

PubChem CID

2913

Molecular Formula

C21H21N

Molecular Weight

287.4 g/mol

Exact Mass

287.1674

InChIKey

JJCFRYNCJDLXIK-UHFFFAOYSA-N

IUPAC Name

1-methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine

SMILES String

CN1CCC(=C2c3ccccc3C=Cc3ccccc32)CC1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Cyproheptadine (CAS 129-03-3) is listed in the Advanced Chemicals portfolio, with molecular formula C21H21N and molecular weight 287. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: 5-hydroxytryptamine receptor 2A (Homo sapiens) — 4 assays; Histamine H1 receptor (Homo sapiens) — 2 assays; Histamine H1 receptor (Cavia porcellus) — 2 assays; 5-hydroxytryptamine receptor 2C (Homo sapiens) — 2 assays; 5-hydroxytryptamine receptor 2B (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 4 documents · best pChEMBL 9.56

Experimental evidence source: ChEMBL

Histamine H1 receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 9.37

Experimental evidence source: ChEMBL

Histamine H1 receptor

Cavia porcellus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 9.27

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2C

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.89

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2B

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.82

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Cyproheptadine

Names & Synonyms

PeriactinolEiproheptadineDronactinCiproheptadinaCyproheptadinum
Show all synonyms
CiprovitMK 1414-(5H-Dibenzo(a,d)cyclohepten-5-ylidene)-1-methylpiperidine1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)piperidine5-(1-Methylpiperidylidene-4)-5H-dibenzo(a,d)cyclopheptene1-Methyl-4-(5-dibenzo(a,e)cycloheptatrienylidene)piperidine4-(5-Dibenzo(a,d)cyclohepten-5-ylidine)-1-methylpiperidine4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidinePiperidine, 4-(5H-dibenzo(a,d)cyclohepten-5-ylidene)-1-methyl-Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-1-Methyl-4-(5H-dibenzo[a,d]cycloheptenylidene)piperidine4-Dibenzo[a,d]cyclohepten-5-ylidene-1-methyl-piperidine4-Dibenzo(a,d)cyclohepten-5-ylidene-1-methyl-piperidineciproeptadina1-methyl-4-(tricyclo(9.4.0.0^(3,8))pentadeca-1(11),3(8),4,6,9,12,14-heptaen-2-ylidene)piperidine
External Identifiers
EC NUMBER: 204-928-9DSSTOX SUBSTANCE ID: DTXSID8022872CHEMBL ID: CHEMBL516CHEBI ID: CHEBI:4046UNII: 2YHB6175DODRUGBANK ID: DB00434HMDB ID: HMDB0014578KEGG ID: C06935KEGG ID: D07765METABOLOMICS WORKBENCH ID: 42791NCI THESAURUS CODE: C61695PHARMGKB ID: PA164749366RXCUI: 3013WIKIDATA ID: Q417884
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchRaman Spectra
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c011782B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 375844062B Determined: The Future of the Serotonin Receptor 2B in Drug Discovery.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

2,3,4,5-tetrahydro-1H-3-benzazepine hydrochlorideCAS 17379-01-0
Thiochroman-4-oneCAS 3528-17-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 111974-69-7QuetiapineCAS 23593-75-1ClotrimazoleCAS 132539-06-1OlanzapineCAS 169590-42-5CelecoxibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 129-03-3

What are the key identifiers for Cyproheptadine (CAS 129-03-3)?

Cyproheptadine is identified by CAS 129-03-3, with molecular formula C21H21N, molecular weight 287.4, InChIKey JJCFRYNCJDLXIK-UHFFFAOYSA-N.

Does CAS 129-03-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with 5-hydroxytryptamine receptor 2A, Histamine H1 receptor, Histamine H1 receptor, 5-hydroxytryptamine receptor 2C, 5-hydroxytryptamine receptor 2B. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 129-03-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Cyproheptadine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 129-03-3 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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