MolGraph
CompoundsDocumentationComplianceAbout
MolGraph

Research chemical sourcing and molecular building block RFQ workflows.

MolGraph is operated by Tessorix Inc.

support@molgraph.com

Products are intended for laboratory research use only and are not for human or veterinary use.

Compounds

  • Compound catalog
  • CAS Search

Company

  • About
  • Contact

Documentation

  • Quality Documentation
  • SDS Disclaimer

Compliance

  • Compliance

Legal

  • Terms
  • Privacy

Copyright © 2026 MolGraph. All Rights Reserved.

Home/Compounds/CAS 129618-40-2
Formula C15H14N4OMW 266.3Research-use catalog entryCOA/SDS by request

Nevirapine

CAS Number: 129618-40-2

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

Available options

Available Options

Package
10 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
100 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
25 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
250 mg
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
5 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
500 g
Purity
98%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required

Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.

Loading RDKit molecule structure...
InChIKey: NQDJXKOVJZTUJA-UHFFFAOYSA-NC15H14N4O | MW 266.3

Chemical Absolute Identifiers

CAS Number

129618-40-2

PubChem CID

4463

Molecular Formula

C15H14N4O

Molecular Weight

266.3 g/mol

Exact Mass

266.116761

InChIKey

NQDJXKOVJZTUJA-UHFFFAOYSA-N

IUPAC Name

2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3,5,7,12,14-hexaen-10-one

SMILES String

CC1=C2C(=NC=C1)N(C3=C(C=CC=N3)C(=O)N2)C4CC4

Physical Properties

Melting Point

196.1 °C

pKa

2.8

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Nevirapine (CAS 129618-40-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C15H14N4O and molecular weight 266. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) — 396 assays; Human immunodeficiency virus type 1 protease (Human immunodeficiency virus 1) — 3 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 4 assays; Cannabinoid receptor 1 (Homo sapiens) — 4 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Human immunodeficiency virus type 1 reverse transcriptase

Human immunodeficiency virus 1 · SINGLE PROTEIN · 396 qualifying assays · 198 documents · best pChEMBL 8.44

Experimental evidence source: ChEMBL

Human immunodeficiency virus type 1 protease

Human immunodeficiency virus 1 · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Cannabinoid receptor 1

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 1A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • The product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
Show additional safety reference fields

Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Nevirapine

Names & Synonyms

ViramuneNevirapine anhydrousViramune XRBIRG 0587Nevirapine, anhydrous
Show all synonyms
Nevirapine teva11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-oneNevirapina11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONENevirapinum anhydrous6H-Dipyrido(3,2-b:2',3'-e)(1,4)diazepin-6-one, 11-cyclopropyl-5,11-dihydro-4-methyl-BI RG 5876H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-nevirapinum2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo(9.4.0.0^(3,8))pentadeca-1(15),3,5,7,11,13-hexaen-10-one2-cyclopropyl-7-methyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3,5,7,11,13-hexaen-10-one2-cyclopropyl-7-methyl-2,4,9,15-tetrazatricyclo(9.4.0.03,8)pentadeca-1(11),3,5,7,12,14-hexaen-10-oneHemihydrate, NevirapineNEVIRAPINE TABLETS FOR ORAL SUSPENSION
External Identifiers
EC NUMBER: 603-345-0DSSTOX SUBSTANCE ID: DTXSID7031797CHEMBL ID: CHEMBL57CHEBI ID: CHEBI:63613UNII: 99DK7FVK1HDRUGBANK ID: DB00238HMDB ID: HMDB0014383KEGG ID: C07263KEGG ID: D00435METABOLOMICS WORKBENCH ID: 42640NCI THESAURUS CODE: C29277PHARMGKB ID: PA450616RXCUI: 53654WIKIDATA ID: Q263713
Experimental Spectrum References
ATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117033Discovery of novel fused-heterocycle-bearing diarypyrimidine derivatives as HIV-1 potent NNRTIs targeting tolerant region I for enhanced antiviral activity and resistance profile.DOI 10.1016/j.ejmech.2025.117271Structure-based discovery of novel diarylpyrimidines as potent and selective Non-Nucleoside reverse transcriptase inhibitors: From CH(CN)-Biphenyl-Diarylpyrimidines to CNNH&lt;sub&gt;2&lt;/sub&gt;-Biphenyl-Diarylpyrimidines.DOI 10.1016/j.ejmech.2025.117464Structure-based design of novel 2,4,5-trisubstituted pyrimidine derivatives as potent HIV-1 NNRTIs by exploiting the tolerant regions in NNTRIs binding pocket.DOI 10.1021/acs.jmedchem.5c00202Deuteration Strategy-Inspired Design of Novel Diarylpyrimidine Derivatives as Potent Non-Nucleoside Reverse Transcriptase Inhibitors Featuring Improved Efficacy, Selectivity, and Druggability.DOI 10.1039/D4MD00469HRapid identification of novel indolylarylsulfone derivatives as potent HIV-1 NNRTIs <i>via</i> miniaturized CuAAC click-chemistry-based combinatorial libraries.PMID 39421538Rapid identification of novel indolylarylsulfone derivatives as potent HIV-1 NNRTIs <i>via</i> miniaturized CuAAC click-chemistry-based combinatorial libraries.PMID 39536498Discovery of novel fused-heterocycle-bearing diarypyrimidine derivatives as HIV-1 potent NNRTIs targeting tolerant region I for enhanced antiviral activity and resistance profile.PMID 39813776Structure-based discovery of novel diarylpyrimidines as potent and selective Non-Nucleoside reverse transcriptase inhibitors: From CH(CN)-Biphenyl-Diarylpyrimidines to CNNH&lt;sub&gt;2&lt;/sub&gt;-Biphenyl-Diarylpyrimidines.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 269055-15-4EtravirineCAS 30516-87-1ZidovudineCAS 117-89-5TrifluoperazineCAS 132539-06-1OlanzapineCAS 500287-72-9RilpivirineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 129618-40-2

What are the key identifiers for Nevirapine (CAS 129618-40-2)?

Nevirapine is identified by CAS 129618-40-2, with molecular formula C15H14N4O, molecular weight 266.3, InChIKey NQDJXKOVJZTUJA-UHFFFAOYSA-N.

Does CAS 129618-40-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Human immunodeficiency virus type 1 reverse transcriptase, Human immunodeficiency virus type 1 protease, Alpha-1A adrenergic receptor, Cannabinoid receptor 1, 5-hydroxytryptamine receptor 1A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 129618-40-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Nevirapine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 129618-40-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.