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Home/Compounds/CAS 1313725-88-0
Formula C17H15N9MW 345.4Research-use catalog entryCOA/SDS by request

Savolitinib

CAS Number: 1313725-88-0

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Loading RDKit molecule structure...
InChIKey: XYDNMOZJKOGZLS-NSHDSACASA-NC17H15N9 | MW 345.4

Chemical Absolute Identifiers

CAS Number

1313725-88-0

PubChem CID

68289010

Molecular Formula

C17H15N9

Molecular Weight

345.4 g/mol

Exact Mass

345.145042

InChIKey

XYDNMOZJKOGZLS-NSHDSACASA-N

IUPAC Name

3-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-5-(1-methylpyrazol-4-yl)triazolo[4,5-b]pyrazine

SMILES String

C[C@@H](c1ccc2nccn2c1)n1nnc2ncc(-c3cnn(C)c3)nc21

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Savolitinib (CAS 1313725-88-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C17H15N9 and molecular weight 345. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Hepatocyte growth factor receptor (Homo sapiens) — 8 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Hepatocyte growth factor receptor

Homo sapiens · SINGLE PROTEIN · 8 qualifying assays · 4 documents · best pChEMBL 8.85

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Savolitinib

Names & Synonyms

VolitinibsavolitinibumAZD 60941-[(1S)-1-imidazo[1,2-a]pyridin-6-ylethyl]-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo[4,5-b]pyrazine1H-1,2,3-Triazolo(4,5-b)pyrazine, 1-((1S)-1-imidazo(1,2-a)pyridin-6-ylethyl)-6-(1-methyl-1H-pyrazol-4-yl)-
Show all synonyms
1-((1S)-1-Imidazo(1,2-a)pyridin-6-ylethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-1,2,3-triazolo(4,5-b)pyrazine3-((1S)-1-imidazo(1,2-a)pyridin-6-ylethyl)-5-(1-methylpyrazol-4-yl)triazolo(4,5-b)pyrazineSavolitinib [INN]Orpathys(S)-1-(1-(imidazo[1,2-a]pyridin-6-yl)ethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1H-[1,2,3]triazolo[4,5-b]pyrazineVolitinib(Savolitinib)HMPL 5044-{1-[(1S)-1-{imidazo[1,2-a]pyridin-6-yl}ethyl]-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl}-1-methyl-1H-pyrazoleSavolitinib (AZD6094)Volitinib dihydrochlorideAZD6094 dihydrochlorideSavolitinib [USAN:INN]Savolitinib dihydrochlorideSAVOLITINIB [USAN]
External Identifiers
EC NUMBER: 810-635-2DSSTOX SUBSTANCE ID: DTXSID801111016CHEMBL ID: CHEMBL3334567CHEBI ID: CHEBI:231369UNII: 2A2DA6857RDRUGBANK ID: DB12048KEGG ID: D11139METABOLOMICS WORKBENCH ID: 153106NCI THESAURUS CODE: C104732PHARMGKB ID: PA166306941WIKIDATA ID: Q27254463
Literature & Patent References
DOI 10.1021/acs.jmedchem.5c00834Discovery of KIN-8741, a Highly Selective Type IIb c-Met Kinase Inhibitor with Broad Mutation Coverage and Quality Drug-Like Properties for the Treatment of Cancer.PMID 40459881Discovery of KIN-8741, a Highly Selective Type IIb c-Met Kinase Inhibitor with Broad Mutation Coverage and Quality Drug-Like Properties for the Treatment of Cancer.DOI 10.1016/j.bmc.2024.117847Recent contributions of pyridazine as a privileged scaffold of anticancer agents in medicinal chemistry: An updated review.DOI 10.1016/j.ejmech.2023.116025Discovery of potent and selective c-Met inhibitors for MET-amplified hepatocellular carcinoma treatment.DOI 10.1021/acsmedchemlett.4c00256Design and Synthesis of c-Met and HDAC Dual Inhibitors for the Treatment of Breast Cancer.PMID 38086189Discovery of potent and selective c-Met inhibitors for MET-amplified hepatocellular carcinoma treatment.PMID 39121679Recent contributions of pyridazine as a privileged scaffold of anticancer agents in medicinal chemistry: An updated review.PMID 39291032Design and Synthesis of c-Met and HDAC Dual Inhibitors for the Treatment of Breast Cancer.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 877399-52-5CrizotinibCAS 1009298-09-2Azd8055CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1313725-88-0

What are the key identifiers for Savolitinib (CAS 1313725-88-0)?

Savolitinib is identified by CAS 1313725-88-0, with molecular formula C17H15N9, molecular weight 345.4, InChIKey XYDNMOZJKOGZLS-NSHDSACASA-N.

Does CAS 1313725-88-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Hepatocyte growth factor receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1313725-88-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Savolitinib?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1313725-88-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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