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Home/Compounds/CAS 1314883-11-8
Formula C18H14F3N3O2SMW 393.4Research-use catalog entryCOA/SDS by request

Mmv-048

CAS Number: 1314883-11-8

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Loading RDKit molecule structure...
InChIKey: RTJQABCNNLMCJF-UHFFFAOYSA-NC18H14F3N3O2S | MW 393.4

Chemical Absolute Identifiers

CAS Number

1314883-11-8

PubChem CID

53311393

Molecular Formula

C18H14F3N3O2S

Molecular Weight

393.4 g/mol

Exact Mass

393.075882

InChIKey

RTJQABCNNLMCJF-UHFFFAOYSA-N

IUPAC Name

5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)-3-pyridinyl]pyridin-2-amine

SMILES String

CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc(C(F)(F)F)nc3)c2)cc1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Mmv-048 (CAS 1314883-11-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C18H14F3N3O2S and molecular weight 393. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Voltage-gated inwardly rectifying potassium channel KCNH2 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Voltage-gated inwardly rectifying potassium channel KCNH2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.33

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Mmv-048

Names & Synonyms

J3.367.891F5-(4-(Methylsulfonyl)phenyl)-6'-(trifluoromethyl)-3,3'-bipyridine-2-amine(3,3'-Bipyridin)-2-amine, 5-(4-(methylsulfonyl)phenyl)-6'-(trifluoromethyl)-5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)pyridin-3-yl]pyridin-2-amine3-(2-(TRIFLUOROMETHYL)PYRIDIN-5-YL)-5-(4-(METHYLSULFONYL)-PHENYL)PYRIDIN-2-AMINE
Show all synonyms
5-(4-methylsulfonylphenyl)-3-(6-(trifluoromethyl)pyridin-3-yl)pyridin-2-amine5-(4-(Methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine5-[4-(methylsulfonyl)phenyl]-6'-(trifluoromethyl)[3,3'-bipyridin]-2-amine5-(4-methylsulfonylphenyl)-3-[6-(trifluoromethyl)-3-pyridyl]pyridin-2-amine3-(2-(Trifluoromethyl)pyridin-5-yl)-5-(4-(methylsulfonyl)- phenyl)pyridin-2-amine5-[4-(Methylsulfonyl)phenyl]-6 inverted exclamation mark -(trifluoromethyl)-[3,3 inverted exclamation mark -bipyridin]-2-amine
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID901352033CHEMBL ID: CHEMBL2041980UNII: 0Z5T00JJ10WIKIDATA ID: Q116457930
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c02799Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual <i>Plasmodium</i> Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.DOI 10.1021/acs.jmedchem.5c00302Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>.PMID 40353796Cell-Based Progression of Spiroindoline Phenotypic Hits Leads to the Identification of Compounds with Diverging Parasitological Profiles against the Human Malaria Parasite <i>Plasmodium falciparum</i>.PMID 40377111Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual <i>Plasmodium</i> Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria.DOI 10.1016/j.ejmech.2024.116354Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein.DOI 10.1016/j.ejmech.2024.116677Optimization of pyrazolopyridine 4-carboxamides with potent antimalarial activity for which resistance is associated with the P. falciparum transporter ABCI3.DOI 10.1021/acs.jmedchem.4c011542,8-Disubstituted-1,5-naphthyridines as Dual Inhibitors of <i>Plasmodium falciparum</i> Phosphatidylinositol-4-kinase and Hemozoin Formation with <i>In Vivo</i> Efficacy.PMID 38554474Activity refinement of aryl amino acetamides that target the P. falciparum STAR-related lipid transfer 1 protein.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1314883-11-8

What are the key identifiers for Mmv-048 (CAS 1314883-11-8)?

Mmv-048 is identified by CAS 1314883-11-8, with molecular formula C18H14F3N3O2S, molecular weight 393.4, InChIKey RTJQABCNNLMCJF-UHFFFAOYSA-N.

Does CAS 1314883-11-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Voltage-gated inwardly rectifying potassium channel KCNH2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1314883-11-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Mmv-048?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1314883-11-8 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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