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Home/Compounds/CAS 132539-06-1
Formula C17H20N4SMW 312.4Research-use catalog entryCOA/SDS by request

Olanzapine

CAS Number: 132539-06-1

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Available options

Available Options

Package
10 ml
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
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Package
100 ml
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
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Package
20 g
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
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Package
5 g
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
Price
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Availability
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Delivery
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Package
5 ml
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
Price
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Availability
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Delivery
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Package
50 ml
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
Price
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Availability
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Delivery
Shipping review required
Package
50 ml
Purity
69.5% With quinoline p-toluenesulfonate; sulfur In benzonitrile at 140℃; for 13.50 h; 向0.118M 2,4-双(4-甲基-1-哌嗪基)-3-丙二酰基-3
Price
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Availability
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Delivery
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Loading RDKit molecule structure...
InChIKey: KVWDHTXUZHCGIO-UHFFFAOYSA-NC17H20N4S | MW 312.4

Chemical Absolute Identifiers

CAS Number

132539-06-1

PubChem CID

135398745

Molecular Formula

C17H20N4S

Molecular Weight

312.4 g/mol

Exact Mass

312.140868

InChIKey

KVWDHTXUZHCGIO-UHFFFAOYSA-N

IUPAC Name

2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine

SMILES String

Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1

Physical Properties

Melting Point

195.0 °C

Boiling Point

476.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Olanzapine (CAS 132539-06-1) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C17H20N4S and molecular weight 312. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Histamine H1 receptor (Homo sapiens) — 13 assays; Histamine H1 receptor (Rattus norvegicus) — 3 assays; 5-hydroxytryptamine receptor 2A (Homo sapiens) — 29 assays; D(2) dopamine receptor (Homo sapiens) — 30 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 10 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Histamine H1 receptor

Homo sapiens · SINGLE PROTEIN · 13 qualifying assays · 13 documents · best pChEMBL 10.06

Experimental evidence source: ChEMBL

Histamine H1 receptor

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 9.52

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 2A

Homo sapiens · SINGLE PROTEIN · 29 qualifying assays · 25 documents · best pChEMBL 9.38

Experimental evidence source: ChEMBL

D(2) dopamine receptor

Homo sapiens · SINGLE PROTEIN · 30 qualifying assays · 28 documents · best pChEMBL 8.68

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 7 documents · best pChEMBL 8.68

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Olanzapine

Names & Synonyms

OlansekZalastaZyprexa ZydisZyprexa VelotabZyprexa Intramuscular
Show all synonyms
olanzapinaOlanzapine Mylan2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepineOlazaxOlanzapine TevaOlazax DisperziOlanzapine GlenmarkolanzapinumLY 170053Olanzapine ciplaOlanzapine apotex10H-thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(4-methyl-1-piperazinyl)-OlanzapinOlanzapine Glenmark Europe
External Identifiers
EC NUMBER: 603-618-4DSSTOX SUBSTANCE ID: DTXSID9023388CHEMBL ID: CHEMBL715CHEBI ID: CHEBI:7735UNII: N7U69T4SZRDRUGBANK ID: DB00334HMDB ID: HMDB0005012KEGG ID: C07322KEGG ID: D00454METABOLOMICS WORKBENCH ID: 53331NCI THESAURUS CODE: C47639PHARMGKB ID: PA450688RXCUI: 61381WIKIDATA ID: Q201872
Experimental Spectrum References
13C NMR Spectra1D NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c02291Rational Design of the First Dual Agonist at Trace Amine-Associated Receptor 1 and 5-HT<sub>2C</sub> Receptors Based on Binding Pocket Similarity for the Treatment of Schizophrenia and Alzheimer's Disease-Related Psychosis.DOI 10.1021/acs.jmedchem.5c00056Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.DOI 10.1039/D4MD00450GMedicinal chemistry-based perspectives on thiophene and its derivatives: exploring structural insights to discover plausible druggable leads.PMID 39601022Medicinal chemistry-based perspectives on thiophene and its derivatives: exploring structural insights to discover plausible druggable leads.PMID 40159850Rational Design of the First Dual Agonist at Trace Amine-Associated Receptor 1 and 5-HT<sub>2C</sub> Receptors Based on Binding Pocket Similarity for the Treatment of Schizophrenia and Alzheimer's Disease-Related Psychosis.PMID 40512599Substrate Specificity of the Organic Cation Transporters MATE1 and MATE2K and Functional Overlap with OCT1 and OCT2.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1021/acs.jmedchem.3c02148First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT&lt;sub&gt;6&lt;/sub&gt; Agents with a Beneficial Neuroprotective Profile against Alzheimer's Disease.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 111974-69-7QuetiapineCAS 23593-75-1ClotrimazoleCAS 21829-25-4NifedipineCAS 109-01-31-MethylpiperazineCAS 106516-24-9SertindoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 132539-06-1

What are the key identifiers for Olanzapine (CAS 132539-06-1)?

Olanzapine is identified by CAS 132539-06-1, with molecular formula C17H20N4S, molecular weight 312.4, InChIKey KVWDHTXUZHCGIO-UHFFFAOYSA-N.

Does CAS 132539-06-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Histamine H1 receptor, Histamine H1 receptor, 5-hydroxytryptamine receptor 2A, D(2) dopamine receptor, Muscarinic acetylcholine receptor M1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 132539-06-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Olanzapine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 132539-06-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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