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Home/Compounds/CAS 1340593-59-0
Formula C23H16F7N5O2MW 527.4Research-use catalog entryCOA/SDS by request

Oteseconazole

CAS Number: 1340593-59-0

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Loading RDKit molecule structure...
InChIKey: IDUYJRXRDSPPRC-NRFANRHFSA-NC23H16F7N5O2 | MW 527.4

Chemical Absolute Identifiers

CAS Number

1340593-59-0

PubChem CID

77050711

Molecular Formula

C23H16F7N5O2

Molecular Weight

527.4 g/mol

Exact Mass

527.119222

InChIKey

IDUYJRXRDSPPRC-NRFANRHFSA-N

IUPAC Name

(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(tetrazol-1-yl)-1-[5-[4-(2,2,2-trifluoroethoxy)phenyl]-2-pyridinyl]propan-2-ol

SMILES String

O[C@@](Cn1cnnn1)(c1ccc(F)cc1F)C(F)(F)c1ccc(-c2ccc(OCC(F)(F)F)cc2)cn1

Physical Properties

Water Solubility

1 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Oteseconazole (CAS 1340593-59-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C23H16F7N5O2 and molecular weight 527. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Cytochrome P450 3A4 (Homo sapiens) — 3 assays; Lanosterol 14-alpha demethylase (Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Cytochrome P450 3A4

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 4.19

Experimental evidence source: ChEMBL

Lanosterol 14-alpha demethylase

Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) · SINGLE PROTEIN · 3 qualifying assays · 3 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Oteseconazole

Names & Synonyms

VIVJOAoteseconazoloteseconazolum(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-1,2,3,4-tetrazol-1-yl)-1-(5-(4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol(R)-2-(2,4-Difluorophenyl)-1,1-Difluoro-3-(1h-Tetrazol-1-Yl)-1-(5-(4-(2,2,2-Trifluoroethoxy)phenyl)pyridin-2-Yl)propan-2-Ol
Show all synonyms
Oteseconazole [USAN](2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(tetrazol-1-yl)-1-[5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl]propan-2-ol2-Pyridineethanol, alpha-(2,4-difluorophenyl)-beta,beta-difluoro-alpha-(1H-tetrazol-1-ylmethyl)-5-(4-(2,2,2-trifluoroethoxy)phenyl)-, (alphaR)-2-Pyridineethanol, alpha-(2,4-difluorophenyl)-beta,beta-difluoro-alpha-(1H-tetrazol-1-ylmethyl)-5-[4-(2,2,2-trifluoroethoxy)phenyl]-, (alphaR)-Vivijoa (TN)Oteseconazole (Standard)OTESECONAZOLE [INN]Oteseconazole (USAN/INN)OTESECONAZOLE, (+)-OTESECONAZOLE [WHO-DD]WHO 10138(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(1H-tetrazol-1-yl)-1-{5-[4-(2,2,2-trifluoroethoxy)phenyl]pyridin-2-yl}propan-2-ol(2R)-2-(2,4-difluorophenyl)-1,1-difluoro-3-(tetrazol-1-yl)-1-[5-[4-(2,2,2-trifluoroethoxy)phenyl]-2-pyridyl]propan-2-ol(alphaR)-alpha-(2,4-Difluorophenyl)-beta,beta-difluoro-alpha-(1H-tetrazol-1-ylmethyl)-5-[4-(2,2,2-trifluoroethoxy)phenyl]-2-pyridineethanol
External Identifiers
EC NUMBER: 841-499-2DSSTOX SUBSTANCE ID: DTXSID401377511CHEMBL ID: CHEMBL3311228CHEBI ID: CHEBI:188153UNII: VHH774W97NDRUGBANK ID: DB13055KEGG ID: D11785METABOLOMICS WORKBENCH ID: 153927NCI THESAURUS CODE: C170270RXCUI: 2602577WIKIDATA ID: Q27291837
Literature & Patent References
DOI 10.1021/acs.jmedchem.5c01068Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors.PMID 40461049Design, Synthesis, and Biological Activity Evaluation of Deuterated Diphenyl Azole Alcohol-Based CYP51 Inhibitors.DOI 10.1016/j.ejmech.2024.116759A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.DOI 10.1021/acs.jmedchem.3c02188Discovery of a Novel Potent Tetrazole Antifungal Candidate with High Selectivity and Broad Spectrum.DOI 10.1021/acs.jmedchem.4c00303Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target.PMID 38598688Discovery of a Novel Potent Tetrazole Antifungal Candidate with High Selectivity and Broad Spectrum.PMID 38683753Identification of Potent and Selective Inhibitors of <i>Acanthamoeba</i>: Structural Insights into Sterol 14α-Demethylase as a Key Drug Target.PMID 39137454A comprehensive review of new small molecule drugs approved by the FDA in 2022: Advance and prospect.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Vt-1598CAS 2089320-99-8
FluconazoleCAS 86386-73-4
Fluconazole hydrateCAS 155347-36-7
VoriconazoleCAS 137234-62-9
Fluconazole (mesylate)CAS 159532-41-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 2089320-99-8Vt-1598CAS 137234-62-9VoriconazoleCAS 171228-49-2PosaconazoleCAS 22916-47-8MiconazoleCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1340593-59-0

What are the key identifiers for Oteseconazole (CAS 1340593-59-0)?

Oteseconazole is identified by CAS 1340593-59-0, with molecular formula C23H16F7N5O2, molecular weight 527.4, InChIKey IDUYJRXRDSPPRC-NRFANRHFSA-N.

Does CAS 1340593-59-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Cytochrome P450 3A4, Lanosterol 14-alpha demethylase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1340593-59-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Oteseconazole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1340593-59-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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