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CAS Number: 134678-17-4
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CAS Number
134678-17-4
PubChem CID
60825
Molecular Formula
C8H11N3O3S
Molecular Weight
229.26 g/mol
Exact Mass
229.052112
InChIKey
JTEGQNOMFQHVDC-NKWVEPMBSA-N
IUPAC Name
4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
SMILES String
C1[C@H](O[C@H](S1)CO)N2C=CC(=NC2=O)N
Melting Point
16–162 °C
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Lamivudine (CAS 134678-17-4) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C8H11N3O3S and molecular weight 229. 26 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1) — 2 assays; Core antigen (Hepatitis B virus) — 12 assays; cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens) — 2 assays; Alpha-1A adrenergic receptor (Homo sapiens) — 6 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Human immunodeficiency virus type 1 reverse transcriptase
Human immunodeficiency virus 1 · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.38
Experimental evidence source: ChEMBL
Core antigen
Hepatitis B virus · SINGLE PROTEIN · 12 qualifying assays · 3 documents · best pChEMBL 6.43
Experimental evidence source: ChEMBL
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.58
Experimental evidence source: ChEMBL
Alpha-1A adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
5-hydroxytryptamine receptor 1A
Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Lamivudine is identified by CAS 134678-17-4, with molecular formula C8H11N3O3S, molecular weight 229.26, InChIKey JTEGQNOMFQHVDC-NKWVEPMBSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Human immunodeficiency virus type 1 reverse transcriptase, Core antigen, cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A, Alpha-1A adrenergic receptor, 5-hydroxytryptamine receptor 1A. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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