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Home/Compounds/CAS 1370468-36-2
Formula C49H55N9O7MW 882Research-use catalog entryCOA/SDS by request

Elbasvir

CAS Number: 1370468-36-2

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Loading RDKit molecule structure...
InChIKey: BVAZQCUMNICBAQ-PZHYSIFUSA-NC49H55N9O7 | MW 882

Chemical Absolute Identifiers

CAS Number

1370468-36-2

PubChem CID

71661251

Molecular Formula

C49H55N9O7

Molecular Weight

882 g/mol

Exact Mass

881.422445

InChIKey

BVAZQCUMNICBAQ-PZHYSIFUSA-N

IUPAC Name

methyl N-[(2S)-1-[(2S)-2-[5-[(6S)-3-[2-[(2S)-1-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]pyrrolidin-2-yl]-1H-imidazol-5-yl]-6-phenyl-6H-indolo[1,2-c][1,3]benzoxazin-10-yl]-1H-imidazol-2-yl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamate

SMILES String

COC(=O)N[C@H](C(=O)N1CCC[C@H]1c1ncc(-c2ccc3c(c2)O[C@@H](c2ccccc2)n2c-3cc3cc(-c4cnc([C@@H]5CCCN5C(=O)[C@@H](NC(=O)OC)C(C)C)[nH]4)ccc32)[nH]1)C(C)C

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Elbasvir (CAS 1370468-36-2) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C49H55N9O7 and molecular weight 882. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nonstructural protein 5A (Hepatitis C virus) — 29 assays; Hepatitis C virus NS5B RNA-dependent RNA polymerase (Hepatitis C virus) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nonstructural protein 5A

Hepatitis C virus · SINGLE PROTEIN · 29 qualifying assays · 7 documents · best pChEMBL 10.7

Experimental evidence source: ChEMBL

Hepatitis C virus NS5B RNA-dependent RNA polymerase

Hepatitis C virus · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Elbasvir

Names & Synonyms

MK 8742elbasvirum2-(pyrrolidin-2-yl)-5-(2-(4-(5-(pyrrolidin-2-yl)-1H-imidazol-2-yl)phenyl)benzofuran-5-yl)-1H-imidazoleElbasvir [USAN]Elbasvir [USAN:INN]
Show all synonyms
Elbasvir (Standard)ELBASVIR [INN]ELBASVIR [JAN]ELBASVIR [MI]ELBASVIR [WHO-DD]Elbasvir(MK-8742)?ELBASVIR [ORANGE BOOK]s5652Dimethyl N,N'-(((6S)-6-phenylindolo(1,2-c)(1,3)benzoxazine-3,10-diyl)bis(1H-imidazole-5,2-diyl-(2S)-pyrrolidine-2,1-diyl((2S)-3-methyl-1-oxobutane-1,2-diyl)))dicarbamateDimethyl N,N'-([(6S)-6H-indolo[1,2-c][1,3]benzoxazine-3,10-diyl]bis{1H-imidazole-5,2-diyl-(2S)-pyrrolidine-2,1-diyl[(2S)-1-oxo-3-met hylbutane-1,2-diyl]})biscarbamate
External Identifiers
EC NUMBER: 806-907-5CHEMBL ID: CHEMBL3039514CHEBI ID: CHEBI:132967UNII: 632L571YDKDRUGBANK ID: DB11574METABOLOMICS WORKBENCH ID: 144567NCI THESAURUS CODE: C166892PHARMGKB ID: PA166163436RXCUI: 1734628WIKIDATA ID: Q19904043
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115919Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.PMID 37922830Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.DOI 10.1021/acs.jmedchem.1c01687Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery.PMID 35060378Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery.DOI 10.1021/acs.jmedchem.1c00790Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 34213340Geminal Diheteroatomic Motifs: Some Applications of Acetals, Ketals, and Their Sulfur and Nitrogen Homologues in Medicinal Chemistry and Drug Design.DOI 10.1101/2020.04.21.054387Identification of potential treatments for COVID-19 through artificial intelligence-enabled phenomic analysis of human cells infected with SARS-CoV-2

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

RuzasvirCAS 1613081-64-3
Daclatasvir DihydrochlorideCAS 1009119-65-6
VelpatasvirCAS 1377049-84-7
LedipasvirCAS 1256388-51-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1613081-64-3RuzasvirCAS 1009119-65-6Daclatasvir DihydrochlorideCAS 1377049-84-7VelpatasvirCAS 1256388-51-8LedipasvirCAS 1350462-55-3GrazoprevirCAS 1132935-63-7DasabuvirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 1370468-36-2

What are the key identifiers for Elbasvir (CAS 1370468-36-2)?

Elbasvir is identified by CAS 1370468-36-2, with molecular formula C49H55N9O7, molecular weight 882, InChIKey BVAZQCUMNICBAQ-PZHYSIFUSA-N.

Does CAS 1370468-36-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nonstructural protein 5A, Hepatitis C virus NS5B RNA-dependent RNA polymerase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1370468-36-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Elbasvir?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 1370468-36-2 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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