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Home/Compounds/CAS 138402-11-6
Formula C25H28N6OMW 428.5Research-use catalog entryCOA/SDS by request

Irbesartan

CAS Number: 138402-11-6

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Loading RDKit molecule structure...
InChIKey: YOSHYTLCDANDAN-UHFFFAOYSA-NC25H28N6O | MW 428.5

Chemical Absolute Identifiers

CAS Number

138402-11-6

PubChem CID

3749

Molecular Formula

C25H28N6O

Molecular Weight

428.5 g/mol

Exact Mass

428.23246

InChIKey

YOSHYTLCDANDAN-UHFFFAOYSA-N

IUPAC Name

2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-1,3-diazaspiro[4.4]non-1-en-4-one

SMILES String

CCCCC1=NC2(CCCC2)C(=O)N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5

Physical Properties

Appearance

Crystals from 96% ethanol

Melting Point

18–181 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Irbesartan (CAS 138402-11-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H28N6O and molecular weight 428. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Type-1 angiotensin II receptor (Homo sapiens) — 29 assays; Type-1 angiotensin II receptor B (Rattus norvegicus) — 3 assays; Leukotriene B4 receptor 2 (Homo sapiens) — 3 assays; Lysosomal alpha-glucosidase (Homo sapiens) — 2 assays; Bile salt export pump (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Type-1 angiotensin II receptor

Homo sapiens · SINGLE PROTEIN · 29 qualifying assays · 13 documents · best pChEMBL 9.1

Experimental evidence source: ChEMBL

Type-1 angiotensin II receptor B

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 9.1

Experimental evidence source: ChEMBL

Leukotriene B4 receptor 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 6.39

Experimental evidence source: ChEMBL

Lysosomal alpha-glucosidase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.35

Experimental evidence source: ChEMBL

Bile salt export pump

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 5.14

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Irbesartan

Names & Synonyms

AvaproAprovelKarveaIrbesartan BMSSR 47436
Show all synonyms
Irbesartan ZentivaSarbevelIrbesartan tevaIrbesartan KrkaIrbesartan Winthrop2-Butyl-3-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-1,3-diazaspiro(4.4)non-1-en-4-one2-butyl-3-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1,3-diazaspiro[4.4]non-1-en-4-one1,3-Diazaspiro(4.4)non-1-en-4-one, 2-butyl-3-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-COAPROVEL COMPONENT IRBESARTAN2-butyl-3-[p-(o-1H-tetrazol-5-ylphenyl)benzyl]-1,3-diazaspiro[4.4]non-1-en-4-oneIFIRMACOMBI COMPONENT IRBESARTANIBERSARTAN/HYDROCHLOROTHIAZIDE COMPONENT IBERSARTANifirmastaIBERSARTAN/HYDROCHLOROTHIAZIDE TEVA COMPONENT IBERSARTAN
External Identifiers
EC NUMBER: 604-078-2DSSTOX SUBSTANCE ID: DTXSID0023169CHEMBL ID: CHEMBL1513CHEBI ID: CHEBI:5959UNII: J0E2756Z7NDRUGBANK ID: DB01029HMDB ID: HMDB0015163KEGG ID: C07469KEGG ID: D00523METABOLOMICS WORKBENCH ID: 43271NCI THESAURUS CODE: C29130PHARMGKB ID: PA450084RXCUI: 83818WIKIDATA ID: Q947266
Experimental Spectrum References
13C NMR Spectra15N NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117093Recent advances in screening methods enabling the discovery of novel anti-hepatitis B virus drug candidates.DOI 10.1021/acs.jmedchem.4c01617Identification of a Chemical Probe for BLT2 Activation by Scaffold Hopping.PMID 39612566Recent advances in screening methods enabling the discovery of novel anti-hepatitis B virus drug candidates.PMID 39803894Identification of a Chemical Probe for BLT2 Activation by Scaffold Hopping.DOI 10.5281/zenodo.13943903Linking interpersonal differences in gut microbiota composition and drug biotransformation activityDOI 10.6019/CHEMBL5442687EUbOPEN Chemogenomics Library - GPCR Dose-ResposeDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724801EUbOPEN Chemogenomics Library - Multiplex

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4'-((2-Butyl-4-oxo-1,3-diazaspiro(4.4)non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrileCAS 138401-24-8
2-Butyl-1,3-diazaspiro[4.4]non-1-en-4-oneCAS 138402-05-8
N-((2'-Cyano-[1,1'-biphenyl]-4-yl)methyl)-1-pentanamidocyclopentanecarboxamideCAS 141745-71-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 138401-24-84'-((2-Butyl-4-oxo-1,3-diazaspiro(4.4)non-1-ene-3-yl)methyl)(1,1'-biphenyl)-2-carbonitrileCAS 139481-59-7CandesartanCAS 75706-12-6LeflunomideCAS 76824-35-6FamotidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 138402-11-6

What are the key identifiers for Irbesartan (CAS 138402-11-6)?

Irbesartan is identified by CAS 138402-11-6, with molecular formula C25H28N6O, molecular weight 428.5, InChIKey YOSHYTLCDANDAN-UHFFFAOYSA-N.

Does CAS 138402-11-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Type-1 angiotensin II receptor, Type-1 angiotensin II receptor B, Leukotriene B4 receptor 2, Lysosomal alpha-glucosidase, Bile salt export pump. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 138402-11-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Irbesartan?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 138402-11-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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