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Home/Compounds/CAS 139481-59-7
Formula C24H20N6O3MW 440.5Research-use catalog entryCOA/SDS by request

Candesartan

CAS Number: 139481-59-7

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Loading RDKit molecule structure...
InChIKey: HTQMVQVXFRQIKW-UHFFFAOYSA-NC24H20N6O3 | MW 440.5

Chemical Absolute Identifiers

CAS Number

139481-59-7

PubChem CID

2541

Molecular Formula

C24H20N6O3

Molecular Weight

440.5 g/mol

Exact Mass

440.159689

InChIKey

HTQMVQVXFRQIKW-UHFFFAOYSA-N

IUPAC Name

2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid

SMILES String

CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)O

Physical Properties

Melting Point

183–185 °C

Water Solubility

7.71 × 10⁻³ g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Candesartan (CAS 139481-59-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C24H20N6O3 and molecular weight 440. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Type-1 angiotensin II receptor (Homo sapiens) — 24 assays; Type-1 angiotensin II receptor (Oryctolagus cuniculus) — 2 assays; Type-1 angiotensin II receptor A (Rattus norvegicus) — 2 assays; Type-1 angiotensin II receptor (Bos taurus) — 3 assays; Adenosine receptor A3 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Type-1 angiotensin II receptor

Homo sapiens · SINGLE PROTEIN · 24 qualifying assays · 8 documents · best pChEMBL 9.4

Experimental evidence source: ChEMBL

Type-1 angiotensin II receptor

Oryctolagus cuniculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 9.19

Experimental evidence source: ChEMBL

Type-1 angiotensin II receptor A

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 8.5

Experimental evidence source: ChEMBL

Type-1 angiotensin II receptor

Bos taurus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 6.96

Experimental evidence source: ChEMBL

Adenosine receptor A3

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.16

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Close tightly.
  • Store in a well-ventilated area.
  • Avoid contact with skin and eyes.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Candesartan

Names & Synonyms

CANDEMORE2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-2-ethoxy-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acid2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid
Show all synonyms
2-ethoxy-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-benzimidazole-7-carboxylic acidcandesartanum2-ethoxy-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)benzimidazole-4-carboxylic acid2-ethoxy-1-((4-(2-(2H-1,2,3,4-tetrazol-5-yl)phenyl)phenyl)methyl)-1H-1,3-benzodiazole-7-carboxylic acid2-ethoxy-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-1,3-benzodiazole-7-carboxylic acid2-ethoxy-1-[[2'-(1h-tetrazol-5-yl)(1,1'-biphenyl)-4-yl]methyl]-1h-benzimidazole-7-carboxylic acid2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole2-Ethoxy-3-((4-(2-(2H-tetrazol-5-yl)phenyl)phenyl)methyl)-3H-benzoimidazole-4-carboxylic Acid1-((2'-(1H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acids15782-ethoxy-1-[[2'-(2h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-benzimidazole-7-carboxylic acid1-((2'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylic acidCV 11974[3H]candesartan
External Identifiers
EC NUMBER: 604-138-8DSSTOX SUBSTANCE ID: DTXSID0022725CHEMBL ID: CHEMBL1016CHEBI ID: CHEBI:3347UNII: S8Q36MD2XXDRUGBANK ID: DB13919HMDB ID: HMDB0014934KEGG ID: C07468KEGG ID: D00522METABOLOMICS WORKBENCH ID: 43087NCI THESAURUS CODE: C65284PHARMGKB ID: PA448765RXCUI: 214354WIKIDATA ID: Q415970
Literature & Patent References
DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1101/2024.03.28.586928Unraveling interindividual differences and functional consequences of gut microbial metabolism of immunosuppressantsDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724562Toxicity screen in isolated B cell assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724581Toxicity screen in purified B cell assay results for EUbOPEN Chemogenomics LibraryPMID 38318365Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnelDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylateCAS 139481-58-6
2-Ethoxy-1-((2'-(1-(triphenylmethyl)-1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acidCAS 139481-72-4
Trityl candesartan cilexetilCAS 170791-09-0
Ethyl 3-amino-2-(((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)amino)benzoateCAS 136285-69-3
Ethyl 2-{[(2'-cyano[1,1'-biphenyl]-4-yl)methyl]amino}-3-nitrobenzoateCAS 136285-67-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 139481-58-6ethyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-ethoxy-1H-benzo[d]imidazole-7-carboxylateCAS 139481-72-42-Ethoxy-1-((2'-(1-(triphenylmethyl)-1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-1H-benzimidazole-7-carboxylic acidCAS 170791-09-0Trityl candesartan cilexetilCAS 138402-11-6IrbesartanCAS 475086-01-2SelexipagCAS 75706-12-6LeflunomideCAS 76824-35-6FamotidineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 139481-59-7

What are the key identifiers for Candesartan (CAS 139481-59-7)?

Candesartan is identified by CAS 139481-59-7, with molecular formula C24H20N6O3, molecular weight 440.5, InChIKey HTQMVQVXFRQIKW-UHFFFAOYSA-N.

Does CAS 139481-59-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Type-1 angiotensin II receptor, Type-1 angiotensin II receptor, Type-1 angiotensin II receptor A, Type-1 angiotensin II receptor, Adenosine receptor A3. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 139481-59-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Candesartan?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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