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Home/Compounds/CAS 1446-61-3
Formula C20H31NMW 285.5Research-use catalog entryCOA/SDS by request

Dehydroabietylamine

CAS Number: 1446-61-3

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Loading RDKit molecule structure...
InChIKey: JVVXZOOGOGPDRZ-SLFFLAALSA-NC20H31N | MW 285.5

Chemical Absolute Identifiers

CAS Number

1446-61-3

PubChem CID

62034

Molecular Formula

C20H31N

Molecular Weight

285.5 g/mol

Exact Mass

285.24565

InChIKey

JVVXZOOGOGPDRZ-SLFFLAALSA-N

IUPAC Name

[(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanamine

SMILES String

CC(C)C1=CC2=C(C=C1)[C@]3(CCC[C@@]([C@@H]3CC2)(C)CN)C

Physical Properties

Melting Point

44.5 °C

Density

1.55 g/cm³

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Dehydroabietylamine (CAS 1446-61-3) is listed in the Catalysts and Ligands portfolio, with molecular formula C20H31N and molecular weight 285. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for catalysis development, ligand screening, and synthetic method research; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Asymmetric SynthesisCatalysis and Ligand ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and reaction.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Dehydroabietylamine

Names & Synonyms

LeelamineAmine DPodocarpa-8,11,13-trien-15-amine, 13-isopropyl-(+)-Dehydroabietylamine(+)-Dehydroabiethylamine
Show all synonyms
((1R,4aS,10aR)-7-Isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methanamine1-Phenanthrenemethanamine, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)-DehydroabiethylamineDehydroabietylamine (>80%)(+)-DEHYDROABIETYLAMINE [OPTICAL RESOLVING AGENT]Caswell No. 276lylamineHSDB 5665(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethylEPA Pesticide Chemical Code 00420613-Isopropylpodocarpa-8,11,13-trien-15-amine4-12-00-03005 (Beilstein Handbook Reference)(+)-Dehydroabietylamine, techDEHYDROABIETYLAMINE [HSDB]
External Identifiers
EC NUMBER: 215-899-7EC NUMBER: 685-075-3DSSTOX SUBSTANCE ID: DTXSID2041834CHEMBL ID: CHEMBL70488CHEBI ID: CHEBI:93086UNII: 33289O147PMETABOLOMICS WORKBENCH ID: 143458WIKIDATA ID: Q15409408
Experimental Spectrum References
13C NMR Spectra — Sigma-Aldrich Co. LLC.1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR SpectraFTIR Spectra — Sigma-Aldrich Co. LLC.Raman Spectra
Literature & Patent References
DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1016/j.ejmech.2018.01.041High anticancer potency on tumor cells of dehydroabietylamine Schiff-base derivatives and a copper(II) complex.DOI 10.1016/j.ejmech.2018.07.051Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity.DOI 10.1039/C8MD00487KSynthesis and potential antineoplastic activity of dehydroabietylamine imidazole derivatives.PMID 29407970High anticancer potency on tumor cells of dehydroabietylamine Schiff-base derivatives and a copper(II) complex.PMID 30056282Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity.PMID 30746067Synthesis and potential antineoplastic activity of dehydroabietylamine imidazole derivatives.DOI 10.1016/j.ejmech.2016.06.004Synthesis and antileishmanial activity of C7- and C12-functionalized dehydroabietylamine derivatives.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(1S)-1-(naphthalen-2-yl)ethan-1-amineCAS 3082-62-0

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 1446-61-3

What are the key identifiers for Dehydroabietylamine (CAS 1446-61-3)?

Dehydroabietylamine is identified by CAS 1446-61-3, with molecular formula C20H31N, molecular weight 285.5, InChIKey JVVXZOOGOGPDRZ-SLFFLAALSA-N.

Does CAS 1446-61-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1446-61-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Dehydroabietylamine?

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