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- 1 mg
- Purity
- 98%
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CAS Number: 1446090-79-4
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CAS Number
1446090-79-4
PubChem CID
89670174
Molecular Formula
C25H17F3N4O3
Molecular Weight
478.4 g/mol
Exact Mass
478.125275
InChIKey
NGFFVZQXSRKHBM-FKBYEOEOSA-N
IUPAC Name
5-[[(1R,1aS,6bR)-1-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-1a,6b-dihydro-1H-cyclopropa[b][1]benzofuran-5-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
SMILES String
C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)O[C@H]5[C@@H]4[C@@H]5C6=NC7=C(N6)C=C(C=C7)C(F)(F)F
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Lifirafenib (CAS 1446090-79-4) is listed in the Advanced Chemicals portfolio, with molecular formula C25H17F3N4O3 and molecular weight 478. 40 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Serine/threonine-protein kinase B-raf (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Serine/threonine-protein kinase B-raf
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.64
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Lifirafenib is identified by CAS 1446090-79-4, with molecular formula C25H17F3N4O3, molecular weight 478.4, InChIKey NGFFVZQXSRKHBM-FKBYEOEOSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Serine/threonine-protein kinase B-raf. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
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