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Home/Compounds/CAS 145572-44-7
Formula C15H22N2OMW 246.35Research-use catalog entryCOA/SDS by request

(-)-Sophocarpine

CAS Number: 145572-44-7

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Loading RDKit molecule structure...
InChIKey: AAGFPTSOPGCENQ-JLNYLFASSA-NC15H22N2O | MW 246.35

Chemical Absolute Identifiers

CAS Number

145572-44-7

PubChem CID

115269

Molecular Formula

C15H22N2O

Molecular Weight

246.35 g/mol

Exact Mass

246.173213

InChIKey

AAGFPTSOPGCENQ-JLNYLFASSA-N

IUPAC Name

(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.02,7.013,17]heptadec-4-en-6-one

SMILES String

C1C[C@H]2CN3[C@H](CC=CC3=O)[C@@H]4[C@H]2N(C1)CCC4

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

(-)-Sophocarpine (CAS 145572-44-7) is listed in the Life Science portfolio, with molecular formula C15H22N2O and molecular weight 246. 35 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

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  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

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Accidental Release

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For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

(-)-Sophocarpine

Names & Synonyms

SophocarpineMatridin-15-one, 13,14-didehydro-1H,5H,10H-Dipyrido(2,1-f:3',2',1'-ij)(1,6)naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, (7aS,13aR,13bR,13cS)-13,14-didehydro-matridin-15-one1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, (7aS,13aR,13bR,13cS)-
Show all synonyms
(1R,2R,9S,17S)-7,13-diazatetracyclo(7.7.1.02,7.013,17)heptadec-4-en-6-one13,14-Didehydromatridin-15-oneSophoridine hydrate(41S,7aS,13aR,13bR)-2,3,41,6,7,7a,8,13,13a,13b-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-oneSophocarpine (monohydrate)13,14-Dehydromatrine13,14-Didehydromatrine(-)-sophocarpinSophocarpine (Standard)Sophocarpine - Bio-X trade marks2405(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0^{2,7}.0^{13,17}]heptadec-4-en-6-oneO0505(1R,2R,9S,17S)-7,13-diazatetracyclo[7.7.1.0?,?.0??,??]heptadec-4-en-6-one
External Identifiers
EC NUMBER: 683-124-3DSSTOX SUBSTANCE ID: DTXSID90215126CHEMBL ID: CHEMBL377725CHEBI ID: CHEBI:228910UNII: X9X8U6P2NPMETABOLOMICS WORKBENCH ID: 133188WIKIDATA ID: Q72508561
Literature & Patent References
DOI 10.1016/j.ejmech.2025.117476Mechanisms and therapeutic strategies for NLRP3 degradation via post-translational modifications in ubiquitin-proteasome and autophagy lysosomal pathway.PMID 40056798Mechanisms and therapeutic strategies for NLRP3 degradation via post-translational modifications in ubiquitin-proteasome and autophagy lysosomal pathway.DOI 10.1016/j.ejmech.2021.113165Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33454546Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation.DOI 10.1016/j.ejmech.2020.112315Structure-activity relationship and hypoglycemic activity of tricyclic matrines with advantage of treating diabetic nephropathy.DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(-)-ThermopsineCAS 486-90-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 100-88-9CyclamateCAS 1000787-75-6TegobuvirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 145572-44-7

What are the key identifiers for (-)-Sophocarpine (CAS 145572-44-7)?

(-)-Sophocarpine is identified by CAS 145572-44-7, with molecular formula C15H22N2O, molecular weight 246.35, InChIKey AAGFPTSOPGCENQ-JLNYLFASSA-N.

Does CAS 145572-44-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 145572-44-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for (-)-Sophocarpine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 145572-44-7 available for quotation?

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