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Home/Compounds/CAS 146-78-1
Formula C10H12FN5O4MW 285.23Research-use catalog entryCOA/SDS by request

2-Fluoroadenosine

CAS Number: 146-78-1

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Loading RDKit molecule structure...
InChIKey: HBUBKKRHXORPQB-UUOKFMHZSA-NC10H12FN5O4 | MW 285.23

Chemical Absolute Identifiers

CAS Number

146-78-1

PubChem CID

8975

Molecular Formula

C10H12FN5O4

Molecular Weight

285.23 g/mol

Exact Mass

285.087332

InChIKey

HBUBKKRHXORPQB-UUOKFMHZSA-N

IUPAC Name

(2R,3R,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

SMILES String

Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

Physical Properties

Water Solubility

42.8 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

2-Fluoroadenosine (CAS 146-78-1) is listed in the Advanced Chemicals portfolio, with molecular formula C10H12FN5O4 and molecular weight 285. 23 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Adenosine receptor A3 (Homo sapiens) — 3 assays; Heat shock factor protein 1 (Mus musculus) — 3 assays; Mothers against decapentaplegic homolog 3 (Homo sapiens) — 4 assays; Geminin (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Adenosine receptor A3

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 7

Experimental evidence source: ChEMBL

Heat shock factor protein 1

Mus musculus · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 6.01

Experimental evidence source: ChEMBL

Mothers against decapentaplegic homolog 3

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Geminin

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

2-Fluoroadenosine

Names & Synonyms

ADENOSINE, 2-FLUORO-6-Amino-2-fluoro-9-beta-D-ribofuranosylpurinePurine, 6-amino-2-fluoro-9-beta-D-ribofuranosyl-(2R,3R,4S,5R)-2-(6-Amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Show all synonyms
2-Far2-FasSRI 727(2R,3R,4S,5R)-2-(6-amino-2-fluoro-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol2FA2-FluoroAdo2-fluoroade-nosinePurine, 6-amino-2-fluoro-9-.beta.-D-ribofuranosyl-cid_89754-26-00-03723 (Beilstein Handbook Reference)(2R,3R,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol6-Amino-2-fluoro-9-(b-D-ribofuranosyl)purine2-FLUORO-9-.BETA.-D-RIBOFURANOSYLADENINE
External Identifiers
EC NUMBER: 633-923-8DSSTOX SUBSTANCE ID: DTXSID70163252CHEMBL ID: CHEMBL290077CHEBI ID: CHEBI:39740UNII: 0S67290CRJDRUGBANK ID: DB04441METABOLOMICS WORKBENCH ID: 56347WIKIDATA ID: Q27095228
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.1021/acs.jmedchem.7b01066Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.PMID 28933546Rational Design of Selective Adenine-Based Scaffolds for Inactivation of Bacterial Histidine Kinases.DOI 10.1021/jm401530aStructure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.PMID 24283924Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.DOI 10.1021/jm020211+Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.PMID 12238926Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.DOI 10.1021/jm00364a023Synthesis and biological evaluation of 2-fluoro-8-azaadenosine and related compounds.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

2-IodoadenosineCAS 35109-88-7
Fludarabine PhosphateCAS 75607-67-9
6-O-MethylinosineCAS 5746-29-2
CladribineCAS 4291-63-8
XanthosineCAS 146-80-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 35109-88-72-IodoadenosineCAS 75607-67-9Fludarabine PhosphateCAS 5746-29-26-O-MethylinosineCAS 4291-63-8CladribineCAS 146-80-5XanthosineCAS 161109-77-9(2R,3R,4S,5R)-2-(Acetoxymethyl)-5-(6-amino-2-fluoro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetateCAS 169590-42-5CelecoxibCAS 21829-25-4NifedipineCAS 22916-47-8MiconazoleCAS 5536-17-4Vidarabine

RFQ questions for CAS 146-78-1

What are the key identifiers for 2-Fluoroadenosine (CAS 146-78-1)?

2-Fluoroadenosine is identified by CAS 146-78-1, with molecular formula C10H12FN5O4, molecular weight 285.23, InChIKey HBUBKKRHXORPQB-UUOKFMHZSA-N.

Does CAS 146-78-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Adenosine receptor A3, Heat shock factor protein 1, Mothers against decapentaplegic homolog 3, Geminin, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 146-78-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 2-Fluoroadenosine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 146-78-1 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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