- Package
- 1 g
- Purity
- 98%
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- Delivery
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CAS Number: 146464-95-1
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CAS Number
146464-95-1
PubChem CID
148121
Molecular Formula
C23H23N7O5
Molecular Weight
477.5 g/mol
Exact Mass
477.176067
InChIKey
OGSBUKJUDHAQEA-WMCAAGNKSA-N
IUPAC Name
(2S)-2-[[4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl]amino]pentanedioic acid
SMILES String
C#CCC(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Water Solubility
6.5 mol/L
pKa
3.25
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Pralatrexate (CAS 146464-95-1) is listed in the Inhibitors and Agonists portfolio, with molecular formula C23H23N7O5 and molecular weight 477. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for biochemical and pharmacology research workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Folate receptor alpha (Homo sapiens) — 2 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Folate receptor alpha
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.78
Experimental evidence source: ChEMBL
Protein deacetylase HDAC6
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Tyrosyl-DNA phosphodiesterase 1
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Pralatrexate is identified by CAS 146464-95-1, with molecular formula C23H23N7O5, molecular weight 477.5, InChIKey OGSBUKJUDHAQEA-WMCAAGNKSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Folate receptor alpha, Protein deacetylase HDAC6, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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