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Home/Compounds/CAS 14949-00-9
Formula C2H4N4O2S2MW 180.21Research-use catalog entryCOA/SDS by request

5-Amino-1,3,4-thiadiazole-2-sulfonamide

CAS Number: 14949-00-9

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Loading RDKit molecule structure...
InChIKey: VGMVBPQOACUDRU-UHFFFAOYSA-NC2H4N4O2S2 | MW 180.21

Chemical Absolute Identifiers

CAS Number

14949-00-9

PubChem CID

84724

Molecular Formula

C2H4N4O2S2

Molecular Weight

180.21 g/mol

Exact Mass

179.977568

InChIKey

VGMVBPQOACUDRU-UHFFFAOYSA-N

SMILES String

C1(=NN=C(S1)S(=O)(=O)N)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5-Amino-1,3,4-thiadiazole-2-sulfonamide (CAS 14949-00-9) is listed in the Advanced Chemicals portfolio, with molecular formula C2H4N4O2S2 and molecular weight 180. 21 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Carbonic anhydrase 7 (Homo sapiens) — 3 assays; Carbonic anhydrase 12 (Homo sapiens) — 5 assays; Carbonic anhydrase 9 (Homo sapiens) — 12 assays; Carbonic anhydrase 15 (Mus musculus) — 2 assays; Carbonic anhydrase 2 (Homo sapiens) — 62 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Carbonic anhydrase 7

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.28

Experimental evidence source: ChEMBL

Carbonic anhydrase 12

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.48

Experimental evidence source: ChEMBL

Carbonic anhydrase 9

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 12 documents · best pChEMBL 7.39

Experimental evidence source: ChEMBL

Carbonic anhydrase 15

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.32

Experimental evidence source: ChEMBL

Carbonic anhydrase 2

Homo sapiens · SINGLE PROTEIN · 62 qualifying assays · 56 documents · best pChEMBL 7.22

Experimental evidence source: ChEMBL

Safety & Handling

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

5-Amino-1,3,4-thiadiazole-2-sulfonamide

Names & Synonyms

5-Amino-TDSNH22-Amino-1,3,4-thiadiazole-5-sulfonamideHats cpdTio-urasinCL 5343
Show all synonyms
1,3,4-Thiadiazole-2-sulfonamide, 5-amino-DESACETYL ACETAZOLAMIDE2-Amino-1,3,4-thiadazole-5-sulfonamide5-amino-1,3,4-thiadiazol-2-sulfonamideZolamide5-Amino-1,3,4-thiadiazol-2-sulfonamide (99%)1,3,4-Thiadiazole-5-sulfonamide, 2-amino-1,3,4-Thiadiazole-2-sulfonamide, 5-amino- (8CI)(9CI)1,3,4-thiadiazole-2-sulfonamide 15aromatic/heteroaromatic sulfonamide 131,3,4-Thiadiazole-2-sulfonamide, 62-Amino-1,4-thiadiazole-5-sulfonamide1,4-Thiadiazole-2-sulfonamide, 5-amino-1,4-Thiadiazole-5-sulfonamide, 2-amino-5-Amino-[1,3,4]thiadiazole-2-sulfonic acid amide
External Identifiers
EC NUMBER: 687-998-7DSSTOX SUBSTANCE ID: DTXSID10164324CHEMBL ID: CHEMBL265674UNII: F687N81LIZHMDB ID: HMDB0246743
Literature & Patent References
DOI 10.1021/acsmedchemlett.2c00471Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to <i>Neisseria gonorrhoeae</i> α-Carbonic Anhydrase.PMID 36655133Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to <i>Neisseria gonorrhoeae</i> α-Carbonic Anhydrase.DOI 10.1021/acsmedchemlett.0c00417In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae.PMID 33214843In Silico-Guided Identification of New Potent Inhibitors of Carbonic Anhydrases Expressed in Vibrio cholerae.DOI 10.1016/j.bmc.2017.05.007Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia.DOI 10.1016/j.bmcl.2016.12.035Sulfonamide inhibition profile of the γ-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis.PMID 28025002Sulfonamide inhibition profile of the γ-carbonic anhydrase identified in the genome of the pathogenic bacterium Burkholderia pseudomallei the etiological agent responsible of melioidosis.PMID 28511911Sulfonamide inhibition profiles of the β-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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Text Reference Cues

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Non-public related references

1,3,4-Thiadiazole-2,5-diamineCAS 2937-81-7
2-Amino-5-bromo-1,3,4-thiadiazoleCAS 37566-39-5
1,3,4-Thiadiazole, 2-amino-5-methyl-CAS 108-33-8
5-Chloro-1,3,4-thiadiazol-2-amineCAS 37566-40-8
2-Amino-5-ethyl-1,3,4-thiadiazoleCAS 14068-53-2

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 2937-81-71,3,4-Thiadiazole-2,5-diamineCAS 37566-39-52-Amino-5-bromo-1,3,4-thiadiazoleCAS 97240-79-4TopiramateCAS 138-41-0CarzenideCAS 169590-42-5CelecoxibCAS 68291-97-4ZonisamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 14949-00-9

What are the key identifiers for 5-Amino-1,3,4-thiadiazole-2-sulfonamide (CAS 14949-00-9)?

5-Amino-1,3,4-thiadiazole-2-sulfonamide is identified by CAS 14949-00-9, with molecular formula C2H4N4O2S2, molecular weight 180.21, InChIKey VGMVBPQOACUDRU-UHFFFAOYSA-N.

Does CAS 14949-00-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Carbonic anhydrase 7, Carbonic anhydrase 12, Carbonic anhydrase 9, Carbonic anhydrase 15, Carbonic anhydrase 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 14949-00-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5-Amino-1,3,4-thiadiazole-2-sulfonamide?

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