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Home/Compounds/CAS 154039-60-8
Formula C15H29N3O5MW 331.41Research-use catalog entryCOA/SDS by request

Marimastat

CAS Number: 154039-60-8

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Loading RDKit molecule structure...
InChIKey: OCSMOTCMPXTDND-OUAUKWLOSA-NC15H29N3O5 | MW 331.41

Chemical Absolute Identifiers

CAS Number

154039-60-8

PubChem CID

119031

Molecular Formula

C15H29N3O5

Molecular Weight

331.41 g/mol

Exact Mass

331.210721

InChIKey

OCSMOTCMPXTDND-OUAUKWLOSA-N

IUPAC Name

(2R,3S)-N-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N',3-dihydroxy-2-(2-methylpropyl)butanediamide

SMILES String

CC(C)C[C@H]([C@@H](C(=O)NO)O)C(=O)N[C@H](C(=O)NC)C(C)(C)C

Physical Properties

Water Solubility

3.38 g/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Marimastat (CAS 154039-60-8) is listed in the Inhibitors and Agonists portfolio, with molecular formula C15H29N3O5 and molecular weight 331. 41 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for biochemical and pharmacology research workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Bioactivity ScreeningResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens) — 11 assays; 72 kDa type IV collagenase (Homo sapiens) — 20 assays; Neutrophil collagenase (Homo sapiens) — 7 assays; Interstitial collagenase (Homo sapiens) — 20 assays; Collagenase 3 (Homo sapiens) — 12 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Disintegrin and metalloproteinase domain-containing protein 17

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 9 documents · best pChEMBL 9.4

Experimental evidence source: ChEMBL

72 kDa type IV collagenase

Homo sapiens · SINGLE PROTEIN · 20 qualifying assays · 20 documents · best pChEMBL 9.39

Experimental evidence source: ChEMBL

Neutrophil collagenase

Homo sapiens · SINGLE PROTEIN · 7 qualifying assays · 7 documents · best pChEMBL 9.33

Experimental evidence source: ChEMBL

Interstitial collagenase

Homo sapiens · SINGLE PROTEIN · 20 qualifying assays · 20 documents · best pChEMBL 9.15

Experimental evidence source: ChEMBL

Collagenase 3

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 12 documents · best pChEMBL 9.13

Experimental evidence source: ChEMBL

Safety & Handling

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus during firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Marimastat

Names & Synonyms

BB 2516KB-R 8898(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoxy)propyl)carboyl)-2-hydroxy-5-methylhexanohydroxamic acidMarimistat(2S,3R)-N-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N',2-dihydroxy-3-(2-methylpropyl)butanediamide
Show all synonyms
marimastatum(2S,3R)-N-((1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl)-N',2-dihydroxy-3-(2-methylpropyl)butanediamide(2S,3R)-3-((S)-(2,2-Dimethyl-1-(methylcarbamoyl) propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acidMarimastat (BB-2516)(2R,3S)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4,3-dihydroxy-2-isobutylsuccinamideMarimastat [USAN]TA 2516(2S,3R)-3-(((1S)-2,2-Dimethyl-1-(methylcarbamoyl)propyl)carbamoyl)-2-hydroxy-5-methylhexanohydroxamic acid(2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamideButanediamide, N4-[(1S)-2,2-dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)-, (2S,3R)-(2R)-N-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-2-[(1S)-1-hydroxy-2-(hydroxyamino)-2-oxo-ethyl]-4-methyl-pentanamide(2s,3r)-N~4~-[(1s)-2,2-Dimethyl-1-(Methylcarbamoyl)propyl]-N~1~,2-Dihydroxy-3-(2-Methylpropyl)butanediamideButanediamide, N4-((1S)-2,2-dimethyl-1-((methylamino)carbonyl)propyl)-N1,2-dihydroxy-3-(2-methylpropyl)-, (2S,3R)-Marimastat (USAN/INN)
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID20165524CHEMBL ID: CHEMBL279785CHEBI ID: CHEBI:50662UNII: D5EQV23TDSDRUGBANK ID: DB00786HMDB ID: HMDB0014924KEGG ID: D03795METABOLOMICS WORKBENCH ID: 43079NCI THESAURUS CODE: C1652PHARMGKB ID: PA164748329WIKIDATA ID: Q6763659
Literature & Patent References
DOI 10.1021/acs.jmedchem.2c02107Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis.PMID 37158732Quinazoline-2-Carboxamides as Selective PET Radiotracers for Matrix Metalloproteinase-13 Imaging in Atherosclerosis.DOI 10.1021/acs.jmedchem.1c01855Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery.DOI 10.1021/acs.jnatprod.2c00626Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.PMID 35969157Selective Inhibitors of Medium-Size S1' Pocket Matrix Metalloproteinases: A Stepping Stone of Future Drug Discovery.PMID 36122348Discovery of Phenolic Matrix Metalloproteinase Inhibitors by Peptide Microarray for Osteosarcoma Treatment.DOI 10.1016/j.ejmech.2021.113623Inhibitors of gelatinases (MMP-2 and MMP-9) for the management of hematological malignancies.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activity

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 154039-60-8

What are the key identifiers for Marimastat (CAS 154039-60-8)?

Marimastat is identified by CAS 154039-60-8, with molecular formula C15H29N3O5, molecular weight 331.41, InChIKey OCSMOTCMPXTDND-OUAUKWLOSA-N.

Does CAS 154039-60-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Disintegrin and metalloproteinase domain-containing protein 17, 72 kDa type IV collagenase, Neutrophil collagenase, Interstitial collagenase, Collagenase 3. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 154039-60-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Marimastat?

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Is CAS 154039-60-8 available for quotation?

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