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Home/Compounds/CAS 1579965-12-0
Formula C21H23N4O7PS2MW 538.5Research-use catalog entryCOA/SDS by request

[2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid

CAS Number: 1579965-12-0

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Loading RDKit molecule structure...
InChIKey: MJLYDVMFNHZMLV-UHFFFAOYSA-NC21H23N4O7PS2 | MW 538.5

Chemical Absolute Identifiers

CAS Number

1579965-12-0

PubChem CID

73386708

Molecular Formula

C21H23N4O7PS2

Molecular Weight

538.5 g/mol

Exact Mass

538.074578

InChIKey

MJLYDVMFNHZMLV-UHFFFAOYSA-N

IUPAC Name

2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinazolin-7-yl]oxyethyl dihydrogen phosphate

SMILES String

CC(C)(C)S(=O)(=O)c1cc2c(Nc3ccc4scnc4c3)ncnc2cc1OCCOP(=O)(O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

[2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid (CAS 1579965-12-0) is listed in the Advanced Chemicals portfolio, with molecular formula C21H23N4O7PS2 and molecular weight 538. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

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Applications & Classification

Organic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Receptor-interacting serine/threonine-protein kinase 2 (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Receptor-interacting serine/threonine-protein kinase 2

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 2 documents · best pChEMBL 9.11

Experimental evidence source: ChEMBL

Safety & Handling

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

[2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid

Names & Synonyms

(2-((4-(1,3-BENZOTHIAZOL-5-YL)AMINO)-6-(2-METHYLPROPANE-2-SULFONYL)QUINAZOLIN-7-YL)OXY)ETHOXY)PHOSPHONIC ACIDGSK2983559 free acid2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphateGSK2983559 (free acid)GSK2983559 (compound 3)
Show all synonyms
2-[[4-(5-benzothiazolylamino)-6-[(1,1-dimethylethyl)sulfonyl]-7-quinazolinyl]oxy]-ethanol, 1-(dihydrogen phosphate)[2-({4-[(1,3-benzothiazol-5-yl)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-yl}oxy)ethoxy]phosphonic acid2-[4-(1,3-benzothiazol-5-ylamino)-6-~{tert}-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphateEthanol, 2-[[4-(5-benzothiazolylamino)-6-[(1,1-dimethylethyl)sulfonyl]-7-quinazolinyl]oxy]-, 1-(dihydrogen phosphate)RIPK2 inhibitor 3GSK-2983559 free acidGSK2983559, free acids8927compound 3 [PMID: 31265286]GSK2983559?Example 1 [WO2014043446A1]2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonyl-quinazolin-7-yl]oxyethyl dihydrogen phosphateK9T
External Identifiers
EC NUMBER: 855-079-1CHEMBL ID: CHEMBL4596287UNII: WJY2LV4368
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115717Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases.PMID 37598483Exploring positions 6 and 7 of a quinazoline-based scaffold leads to changes in selectivity and potency towards RIPK2/3 kinases.DOI 10.1016/j.bmcl.2022.128968Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors.PMID 36058467Design, synthesis, and structure-activity relationship of novel RIPK2 inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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  1. 1We review the CAS identity, quantity, and documentation request.
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Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1579965-12-0

What are the key identifiers for [2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid (CAS 1579965-12-0)?

[2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid is identified by CAS 1579965-12-0, with molecular formula C21H23N4O7PS2, molecular weight 538.5, InChIKey MJLYDVMFNHZMLV-UHFFFAOYSA-N.

Does CAS 1579965-12-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Receptor-interacting serine/threonine-protein kinase 2. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1579965-12-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for [2-({4-[1,3-Benzothiazol-5-YL)amino]-6-(2-methylpropane-2-sulfonyl)quinazolin-7-YL}oxy)ethoxy}phosphonic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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