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Home/Compounds/CAS 159803-11-9
Formula C7H4FNOSMW 169.18Research-use catalog entryCOA/SDS by request

6-Fluoro-1,2-benzothiazol-3(2H)-one

CAS Number: 159803-11-9

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Available options

Available Options

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Purity
96%
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Purity
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Loading RDKit molecule structure...
InChIKey: WLQRIPHXCTXOQC-UHFFFAOYSA-NC7H4FNOS | MW 169.18

Chemical Absolute Identifiers

CAS Number

159803-11-9

PubChem CID

480272

Molecular Formula

C7H4FNOS

Molecular Weight

169.18 g/mol

Exact Mass

168.999763

InChIKey

WLQRIPHXCTXOQC-UHFFFAOYSA-N

IUPAC Name

6-fluoro-1,2-benzothiazol-3-one

SMILES String

C1=CC2=C(C=C1F)SNC2=O

Physical Properties

Water Solubility

22.7 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

6-Fluoro-1,2-benzothiazol-3(2H)-one (CAS 159803-11-9) is listed in the Advanced Chemicals portfolio, with molecular formula C7H4FNOS and molecular weight 169. 18 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Nuclear receptor ROR-gamma (Mus musculus) — 2 assays; Replicase polyprotein 1ab (Severe acute respiratory syndrome coronavirus 2) — 2 assays; Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (Plasmodium berghei) — 3 assays; Microtubule-associated protein tau (Homo sapiens) — 2 assays; ATP-dependent 6-phosphofructokinase (Trypanosoma brucei) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Nuclear receptor ROR-gamma

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.65

Experimental evidence source: ChEMBL

Replicase polyprotein 1ab

Severe acute respiratory syndrome coronavirus 2 · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.64

Experimental evidence source: ChEMBL

Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase

Plasmodium berghei · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 5.01

Experimental evidence source: ChEMBL

Microtubule-associated protein tau

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.95

Experimental evidence source: ChEMBL

ATP-dependent 6-phosphofructokinase

Trypanosoma brucei · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

6-Fluoro-1,2-benzothiazol-3(2H)-one

Names & Synonyms

6-Fluorobenzo[d]isothiazol-3(2H)-one6-Fluoro-1,2-benzoisothiazol-3(2H)-one1,2-Benzisothiazol-3(2H)-one, 6-fluoro-6-fluorobenzisothiazol-3(2H)-one6-fluoro-1,2-benzisothiazol-3(2H)-one
Show all synonyms
6-fluorobenzo[d]isothiazol-3[2H]-one6-fluoro-2,3-dihydro-1,2-benzothiazol-3-one6-Fluoro-benzo[d]isothiazol-3-oneA1EEBcid_480272REGID_for_CID_4802726-fluoranyl-1,2-benzothiazol-3-ones105631,2-Benzisothiazol[6-fluoro-3(2H)-ones]
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID40333081CHEMBL ID: CHEMBL1532997WIKIDATA ID: Q82098170
Literature & Patent References
DOI 10.1016/j.bmcl.2022.128526Discovery of highly potent SARS-CoV-2 M<sup>pro</sup> inhibitors based on benzoisothiazolone scaffold.PMID 34998903Discovery of highly potent SARS-CoV-2 M<sup>pro</sup> inhibitors based on benzoisothiazolone scaffold.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

1,2-Benzothiazolin-3-one, 6-methyl-CAS 4337-47-7
5-Chloroisothiazol-3-olCAS 25629-58-7
3-Hydroxy-1,2-thiazole-5-carboxylic acidCAS 1257444-26-0
Isothiazolin-3-oneCAS 1003-07-2
1,2-Thiazol-5(2H)-oneCAS 82357-89-9

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 4337-47-71,2-Benzothiazolin-3-one, 6-methyl-CAS 2527-03-92-phenyl-1,2-benzisothiazol-3-(2H)-oneCAS 60940-34-3EbselenCAS 50-65-7NiclosamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 159803-11-9

What are the key identifiers for 6-Fluoro-1,2-benzothiazol-3(2H)-one (CAS 159803-11-9)?

6-Fluoro-1,2-benzothiazol-3(2H)-one is identified by CAS 159803-11-9, with molecular formula C7H4FNOS, molecular weight 169.18, InChIKey WLQRIPHXCTXOQC-UHFFFAOYSA-N.

Does CAS 159803-11-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Nuclear receptor ROR-gamma, Replicase polyprotein 1ab, Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase, Microtubule-associated protein tau, ATP-dependent 6-phosphofructokinase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 159803-11-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 6-Fluoro-1,2-benzothiazol-3(2H)-one?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 159803-11-9 available for quotation?

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