Research chemical
CAS Number: 160970-54-7
Product details
For laboratory research and professional procurement workflows.
PubChem CID
5312125
Exact Mass
495.234491
InChIKey
PNCPYILNMDWPEY-QGZVFWFLSA-N
IUPAC Name
1-(3-hydroxypropyl)-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide
SMILES String
C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F
Melting Point
105–109 °C
Water Solubility
1 mol/L
XLogP
3.6
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Heavy atom count
35
H-bond acceptors
7
H-bond donors
4
Rotatable bonds
13
Ring count
3
Aromatic rings
2
Topological polar surface area
97.05 Ų
Computed LogP
3.07
Structural features
Silodosin (CAS 160970-54-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H32F3N3O4 and molecular weight 495. 50 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
SDS signal word: Warning; hazard codes: H302, H315, H319, H335; For research use only.
ChEMBL reports experimental activity evidence for: Alpha-1A adrenergic receptor (Homo sapiens) — 10 assays; Alpha-1D adrenergic receptor (Homo sapiens) — 5 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 3 assays; Alpha-1B adrenergic receptor (Homo sapiens) — 5 assays; Beta-2 adrenergic receptor (Homo sapiens) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Procurement notes
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Use the quote panel for visible public options. Additional quantities or specifications can be reviewed by RFQ.
Purity, lot identity, and batch-specific documentation are confirmed before procurement decisions.
Supplier-issued COA and SDS can be requested before handling, storage, shipment, or procurement decisions.
Final quote depends on quantity, lead time, destination, and supplier confirmation.
Silodosin is listed as in-stock / available for research-use sourcing review. Final availability, lot specification, and lead time are confirmed by RFQ.
The page shows a public reference price in the quote panel. Submit an RFQ to confirm current price, quantity breaks, lead time, and destination-specific shipping requirements.
Yes. Supplier-issued COA and SDS can be requested during the RFQ workflow. Lot-specific documents depend on supplier and batch confirmation.
Fragment-like structure rule
No
Lead-like structure rule
No
Drug-like structure rule
Yes
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
No
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Alpha-1A adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 7 documents · best pChEMBL 10.44
Experimental evidence source: ChEMBL
Alpha-1D adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 8.7
Experimental evidence source: ChEMBL
5-hydroxytryptamine receptor 1A
Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.52
Experimental evidence source: ChEMBL
Alpha-1B adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.7
Experimental evidence source: ChEMBL
Beta-2 adrenergic receptor
Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 7.48
Experimental evidence source: ChEMBL
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.
Preliminary Safety Reference
For supplier-issued SDS or COA, submit a documentation request.
Safety Reference / SDS RequestSignal word: Warning
Supplier SDS reference cue; confirm supplier documentation before use.
Hazard statements: H302, H315, H319, H335
Supplier SDS hazard code reference; confirm full text in supplier documentation.
Precautionary statements: P261, P305+P351+P338
Supplier SDS precautionary code reference; confirm full text in supplier documentation.
Shipment review: Required
Certificate of Analysis (COA): By request
Supplier Safety Data Sheet (SDS): By request
Purity and pack size confirmation: By request
Availability and lead time review: Confirmed by RFQ
Shipment documentation review: By request
For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference
Additional text reference cues are not available for this catalog entry.
Non-public references are shown as text only and do not imply equivalence, availability, or shared use.