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Home/Compounds/CAS 160970-54-7
Formula C25H32F3N3O4MW 495.5Research-use catalog entryCOA/SDS by request

Silodosin

CAS Number: 160970-54-7

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Loading RDKit molecule structure...
InChIKey: PNCPYILNMDWPEY-QGZVFWFLSA-NC25H32F3N3O4 | MW 495.5

Chemical Absolute Identifiers

CAS Number

160970-54-7

PubChem CID

5312125

Molecular Formula

C25H32F3N3O4

Molecular Weight

495.5 g/mol

Exact Mass

495.234491

InChIKey

PNCPYILNMDWPEY-QGZVFWFLSA-N

IUPAC Name

1-(3-hydroxypropyl)-5-[(2R)-2-[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethylamino]propyl]-2,3-dihydroindole-7-carboxamide

SMILES String

C[C@H](Cc1cc2c(c(C(N)=O)c1)N(CCCO)CC2)NCCOc1ccccc1OCC(F)(F)F

Physical Properties

Melting Point

105–109 °C

Water Solubility

1 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Silodosin (CAS 160970-54-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C25H32F3N3O4 and molecular weight 495. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Alpha-1A adrenergic receptor (Homo sapiens) — 10 assays; Alpha-1D adrenergic receptor (Homo sapiens) — 5 assays; 5-hydroxytryptamine receptor 1A (Homo sapiens) — 3 assays; Alpha-1B adrenergic receptor (Homo sapiens) — 5 assays; Beta-2 adrenergic receptor (Homo sapiens) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 7 documents · best pChEMBL 10.44

Experimental evidence source: ChEMBL

Alpha-1D adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 8.7

Experimental evidence source: ChEMBL

5-hydroxytryptamine receptor 1A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Alpha-1B adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 7.7

Experimental evidence source: ChEMBL

Beta-2 adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 7.48

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Silodosin

Names & Synonyms

UriefRapafloSilodyxUrorecRapilif
Show all synonyms
SilodalsilodosineSilodosina1-(3-hydroxypropyl)-5-[(2r)-2-({2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl}amino)propyl]-2,3-dihydro-1h-indole-7-carboxamide1-(3-hydroxypropyl)-5-(2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)indoline-7-carboxamidesilodosinum1-(3-Hydroxypropyl)-5-((2R)-2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)-2,3-dihydro-1H-indole-7-carboxamide1-(3-hydroxypropyl)-5-((2R)-2-(2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethylamino)propyl)-2,3-dihydroindole-7-carboxamideKMD 3213(-)-1-(3-Hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-di-hydro-1H-indole-7-carboxamide(R)-1-(3-hydroxypropyl)-5-(2-((2-(2-(2,2,2-trifluoroethoxy)phenoxy)ethyl)amino)propyl)indoline-7-carboxamide1H-Indole-7-carboxamide, 2,3-dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamideRapflo
External Identifiers
EC NUMBER: 814-909-2DSSTOX SUBSTANCE ID: DTXSID40167045CHEMBL ID: CHEMBL24778CHEBI ID: CHEBI:135929UNII: CUZ39LUY82DRUGBANK ID: DB06207KEGG ID: D01965METABOLOMICS WORKBENCH ID: 149678NCI THESAURUS CODE: C81372PHARMGKB ID: PA165291889RXCUI: 720825WIKIDATA ID: Q411770
Literature & Patent References
DOI 10.6019/CHEMBL5442175EUbOPEN Chemogenomics Library - PDSP Secondary BindingDOI 10.6019/CHEMBL5442219EUbOPEN Chemogenomics Library - PDSP Primary BindingDOI 10.6019/CHEMBL5442687EUbOPEN Chemogenomics Library - GPCR Dose-ResposeDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724696Autophagy assay results for EUbOPEN Chemogenomics LibraryDOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.DOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

5-[(2R)-2-aminopropyl]-1-[3-(benzoyloxy)propyl]-2,3-dihydro-1H-Indole-7-carbonitrileCAS 239463-72-0
3-(7-Cyano-5-(2-nitropropyl)indolin-1-yl)propyl benzoateCAS 350797-56-7
1-(3-(Benzyloxy)propyl)-5-(2-oxopropyl)indoline-7-carbonitrileCAS 1096141-50-2
1-Methoxy-2-(2,2,2-trifluoroethoxy)benzeneCAS 106854-74-4
1-(2-Bromoethoxy)-2-(2,2,2-trifluoroethoxy)benzeneCAS 160969-00-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 79307-93-0Azelastine HydrochlorideCAS 879085-55-9VismodegibCAS 274693-27-5TicagrelorCAS 4205-91-8Clonidine HydrochlorideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 160970-54-7

What are the key identifiers for Silodosin (CAS 160970-54-7)?

Silodosin is identified by CAS 160970-54-7, with molecular formula C25H32F3N3O4, molecular weight 495.5, InChIKey PNCPYILNMDWPEY-QGZVFWFLSA-N.

Does CAS 160970-54-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, 5-hydroxytryptamine receptor 1A, Alpha-1B adrenergic receptor, Beta-2 adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 160970-54-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Silodosin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 160970-54-7 available for quotation?

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