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Home/Compounds/CAS 163252-36-6
Formula C10H13FN2O5MW 260.22Research-use catalog entryCOA/SDS by request

Clevudine

CAS Number: 163252-36-6

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Loading RDKit molecule structure...
InChIKey: GBBJCSTXCAQSSJ-XQXXSGGOSA-NC10H13FN2O5 | MW 260.22

Chemical Absolute Identifiers

CAS Number

163252-36-6

PubChem CID

73115

Molecular Formula

C10H13FN2O5

Molecular Weight

260.22 g/mol

Exact Mass

260.08085

InChIKey

GBBJCSTXCAQSSJ-XQXXSGGOSA-N

IUPAC Name

1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

SMILES String

CC1=CN(C(=O)NC1=O)[C@@H]2[C@@H]([C@H]([C@@H](O2)CO)O)F

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Clevudine (CAS 163252-36-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C10H13FN2O5 and molecular weight 260. 22 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Alpha-1A adrenergic receptor (Homo sapiens) — 2 assays; Muscarinic acetylcholine receptor M1 (Homo sapiens) — 2 assays; Prostaglandin G/H synthase 1 (Homo sapiens) — 2 assays; Thromboxane A2 receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Alpha-1A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Muscarinic acetylcholine receptor M1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Prostaglandin G/H synthase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Thromboxane A2 receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

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  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity and stability.
  • Carbon monoxide, carbon dioxide, hydrogen fluoride, nitrogen oxides.

Disposal

  • Dispose of remaining and non-recyclable solutions to a licensed company.
  • Contact a professional agency with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Clevudine

Names & Synonyms

L-FMAULevovirRevovir1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine2'-Fluoro-5-methyl-beta-L-arabinofuranosyluracil
Show all synonyms
1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione1-((2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione1-(2-fluoro-beta-L-arabinofuranosyl)thymine1-(2-fluoro-5-methyl-beta,L-arabinofuranosyl)uracil1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dioneClevudine (USAN)2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-beta-L-arabinofuranosyl)-5-methyl-1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dioneCLEVUDINE [USAN]2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-2-fluoro-.beta.-L-arabinofuranosyl)-5-methyl-Clevudine [USAN:INN]ClevudinaClevudine (Levovir)
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID2057659CHEMBL ID: CHEMBL458875CHEBI ID: CHEBI:135964UNII: IN51MVP5F1DRUGBANK ID: DB06683KEGG ID: D03537METABOLOMICS WORKBENCH ID: 149897NCI THESAURUS CODE: C95210PHARMGKB ID: PA166198261WIKIDATA ID: Q1100864
Literature & Patent References
DOI 10.1016/j.ejmech.2023.115919Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.DOI 10.1038/s41467-023-40064-9A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37468498A preclinical secondary pharmacology resource illuminates target-adverse drug reaction associations of marketed drugs.PMID 37922830Synthetic approaches and application of clinically approved small-molecule drugs to treat hepatitis.DOI 10.1186/s13148-021-01037-1Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33691794Synergistic effects of type I PRMT and PARP inhibitors against non-small cell lung cancer cells.DOI 10.1016/j.ejmech.2020.112801Therapeutic potential of uracil and its derivatives in countering pathogenic and physiological disorders.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

TelbivudineCAS 3424-98-4
3'-Fluoro-2',3'-dideoxyguanosineCAS 92562-88-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 3424-98-4TelbivudineCAS 100-33-4PentamidineCAS 100643-71-8DesloratadineCAS 102767-28-2LevetiracetamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 163252-36-6

What are the key identifiers for Clevudine (CAS 163252-36-6)?

Clevudine is identified by CAS 163252-36-6, with molecular formula C10H13FN2O5, molecular weight 260.22, InChIKey GBBJCSTXCAQSSJ-XQXXSGGOSA-N.

Does CAS 163252-36-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Alpha-1A adrenergic receptor, Muscarinic acetylcholine receptor M1, Prostaglandin G/H synthase 1, Thromboxane A2 receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 163252-36-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Clevudine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 163252-36-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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