(2,6-Bis(trifluoromethyl)pyridin-4-yl)boronic acid

(2,6-Bis(trifluoromethyl)pyridin-4-yl)boronic acid, with CAS 1653975-45-1, is a specialized organoboron compound characterized by a pyridine core substituted with two electron-withdrawing trifluoromethyl groups at positions 2 and 6, and a boronic acid group at position 4. The presence of the trifluoromethyl groups significantly influences the electronic properties of the pyridine ring, making it a valuable reagent in synthetic methodologies. Boronic acids are widely utilized in various cross-coupling reactions, such as the Suzuki-Miyaura coupling, for forming carbon-carbon bonds. This compound is particularly useful for introducing a fluorinated pyridine moiety into target molecules, which can be advantageous in medicinal chemistry and materials science for modifying physicochemical properties like lipophilicity, metabolic stability, and binding affinity. This product is for research use only.

• Handle (2,6-Bis(trifluoromethyl)pyridin-4-yl)boronic acid with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. This chemical is for research use only and not for human or animal therapeutic or diagnostic use.