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Home/Compounds/CAS 165800-03-3
Formula C16H20FN3O4MW 337.35Research-use catalog entryCOA/SDS by request

Linezolid

CAS Number: 165800-03-3

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Loading RDKit molecule structure...
InChIKey: TYZROVQLWOKYKF-ZDUSSCGKSA-NC16H20FN3O4 | MW 337.35

Chemical Absolute Identifiers

CAS Number

165800-03-3

PubChem CID

441401

Molecular Formula

C16H20FN3O4

Molecular Weight

337.35 g/mol

Exact Mass

337.143784

InChIKey

TYZROVQLWOKYKF-ZDUSSCGKSA-N

IUPAC Name

N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

SMILES String

CC(=O)NC[C@H]1CN(c2ccc(N3CCOCC3)c(F)c2)C(=O)O1

Physical Properties

Melting Point

181.5–182.5 °C

pKa

1.8

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Linezolid (CAS 165800-03-3) is listed in the Advanced Chemicals portfolio, with molecular formula C16H20FN3O4 and molecular weight 337. 35 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Streptokinase A (Streptococcus pyogenes serotype M1) — 2 assays; Amine oxidase [flavin-containing] A (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Streptokinase A

Streptococcus pyogenes serotype M1 · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.8

Experimental evidence source: ChEMBL

Amine oxidase [flavin-containing] A

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 4.7

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Linezolid

Names & Synonyms

ZyvoxLINEZOLIDEN-(((S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl)methyl)acetamideU-100,766Acetamide, N-((3-(3-fluoro-4-(4-morpholinyl)phenyl)-2-oxo-5-oxazolidinyl)methyl)-, (S)-
Show all synonyms
N-{[(5s)-3-(3-Fluoro-4-Morpholin-4-Ylphenyl)-2-Oxo-1,3-Oxazolidin-5-Yl]methyl}acetamideN-({(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl}methyl)acetamideN-{[(5S)-3-[3-fluoro-4-(morpholin-4-yl)phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamideLinezolidumAcetamide, N-[[3-[3-fluoro-4-(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, (S)-N-(((5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamideN-[[(S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-5-oxazolidinyl]methyl]acetamideN-(((5S)-3-(3-fluoro-4-(morpholin-4-yl)phenyl)-2-oxo-1,3-oxazolidin-5-yl)methyl)acetamideN-((3-(3-fluoro-4-morpholinylphenyl)-2-oxo-5-oxazolidinyl)methyl)acetamide100766, ULINEZOLID IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER(S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamideZyvoxidZyvoxam
External Identifiers
EC NUMBER: 605-416-1DSSTOX SUBSTANCE ID: DTXSID5046489CHEMBL ID: CHEMBL126CHEBI ID: CHEBI:63607UNII: ISQ9I6J12JDRUGBANK ID: DB00601HMDB ID: HMDB0014739KEGG ID: C08146KEGG ID: D00947METABOLOMICS WORKBENCH ID: 42931NCI THESAURUS CODE: C29158PHARMGKB ID: PA450233RXCUI: 190376WIKIDATA ID: Q411377
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1016/j.bmcl.2010.11.022The discovery and structure-activity relationships leading to CE-156811, a difluorophenyl cyclopropyl fluoroether: a novel potent antibacterial analog derived from hygromycin A.DOI 10.1016/j.bmcl.2010.11.043MDCK cell permeability characteristics of a sulfenamide prodrug: strategic implications in considering sulfenamide prodrugs for oral delivery of NH-acids.DOI 10.1016/j.bmcl.2010.11.102Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.DOI 10.1016/j.bmcl.2011.03.075Synthesis and in vitro activity of novel 1,2,4-triazolo[4,3-a]pyrimidine oxazolidinone antibacterial agents.DOI 10.1016/j.ejmech.2010.10.015Discovery of a novel nitroimidazolyl-oxazolidinone hybrid with potent anti Gram-positive activity: Synthesis and antibacterial evaluation.DOI 10.1016/j.ejmech.2010.12.028Anti-tubercular agents. Part 6: synthesis and antimycobacterial activity of novel arylsulfonamido conjugated oxazolidinones.DOI 10.1016/j.ejmech.2011.01.014Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent.DOI 10.1021/jm1014023A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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Text Reference Cues

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Non-public related references

(S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)ethanethioamideCAS 216868-57-4
(S)-N-((3-(3-fluoro-4-(piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamideCAS 154590-66-6
(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-oneCAS 168828-82-8
(S)-N-[3-(3-Fluoro-4-iodo-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamideCAS 149524-45-8
5-(Chloromethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one, (R)-CAS 496031-57-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 216868-57-4(S)-N-((3-(3-Fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)ethanethioamideCAS 154590-66-6(S)-N-((3-(3-fluoro-4-(piperazin-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamideCAS 168828-82-8(5R)-3-(3-fluoro-4-morpholin-4-ylphenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-oneCAS 149524-45-8(S)-N-[3-(3-Fluoro-4-iodo-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamideCAS 496031-57-35-(Chloromethyl)-3-(3-fluoro-4-morpholinophenyl)oxazolidin-2-one, (R)-CAS 106516-24-9SertindoleCAS 154361-50-9CapecitabineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 165800-03-3

What are the key identifiers for Linezolid (CAS 165800-03-3)?

Linezolid is identified by CAS 165800-03-3, with molecular formula C16H20FN3O4, molecular weight 337.35, InChIKey TYZROVQLWOKYKF-ZDUSSCGKSA-N.

Does CAS 165800-03-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Streptokinase A, Amine oxidase [flavin-containing] A. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 165800-03-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Linezolid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 165800-03-3 available for quotation?

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