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Home/Compounds/CAS 16874-81-0
Formula C15H18N4O3MW 302.33Research-use catalog entryCOA/SDS by request

Histidylphenylalanine

CAS Number: 16874-81-0

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Available Options

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Purity
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Loading RDKit molecule structure...
InChIKey: XMAUFHMAAVTODF-STQMWFEESA-NC15H18N4O3 | MW 302.33

Chemical Absolute Identifiers

CAS Number

16874-81-0

PubChem CID

152198

Molecular Formula

C15H18N4O3

Molecular Weight

302.33 g/mol

Exact Mass

302.13789

InChIKey

XMAUFHMAAVTODF-STQMWFEESA-N

IUPAC Name

(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoic acid

SMILES String

N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Histidylphenylalanine (CAS 16874-81-0) is listed in the Life Science portfolio, with molecular formula C15H18N4O3 and molecular weight 302. 33 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchPeptide ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Neurolysin, mitochondrial (Rattus norvegicus) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Neurolysin, mitochondrial

Rattus norvegicus · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.13

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Histidylphenylalanine

Names & Synonyms

l-histidyl-l-phenylalanineHis-phePhenylalanylhistidineH-His-Phe-OHL-Phenylalanine, L-histidyl-
Show all synonyms
HF dipeptideH-F DipeptideHistidine Phenylalanine dipeptideHistidyl-phenylalanineHistidinylphenylalanineN-histidyl-phenylalanineL-Histidinyl-L-PhenylalanineN-L-histidyl-L-phenylalanineHistidine-Phenylalanine dipeptideL-Phenylalanine, N-L-histidyl-(S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)Propanamido)-3-phenylPropanoic acid(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenyl-propanoic acid(2S)-2-[[(2S)-2-azaniumyl-3-(1H-imidazol-5-yl)propanoyl]amino]-3-phenylpropanoate(2S)-2-{[(2S)-2-amino-3-(1H-imidazol-4-yl)propanoyl]amino}-3-phenylpropanoic acid
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID70168606CHEMBL ID: CHEMBL1222393CHEBI ID: CHEBI:141438HMDB ID: HMDB0028892METABOLOMICS WORKBENCH ID: 78829
Literature & Patent References
DOI 10.1021/acsmedchemlett.4c00009Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability.PMID 38628788Imidazole Bioisostere Activators of Endopeptidase Neurolysin with Enhanced Potency and Metabolic Stability.DOI 10.1021/acs.jmedchem.1c00759Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability.PMID 34436882Discovery of First-in-Class Peptidomimetic Neurolysin Activators Possessing Enhanced Brain Penetration and Stability.DOI 10.1038/nchembio.132Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.PMID 19060912Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

His-AspCAS 41658-60-0
H-His-Lys-OH.HBrCAS 151151-29-0
Ala-HisCAS 3253-17-6
L-Aspartyl-L-phenylalanineCAS 13433-09-5
Phe-AspCAS 22828-05-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 41658-60-0His-AspCAS 151151-29-0H-His-Lys-OH.HBrCAS 3253-17-6Ala-HisCAS 13433-09-5L-Aspartyl-L-phenylalanineCAS 22828-05-3Phe-AspCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 16874-81-0

What are the key identifiers for Histidylphenylalanine (CAS 16874-81-0)?

Histidylphenylalanine is identified by CAS 16874-81-0, with molecular formula C15H18N4O3, molecular weight 302.33, InChIKey XMAUFHMAAVTODF-STQMWFEESA-N.

Does CAS 16874-81-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Neurolysin, mitochondrial. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 16874-81-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Histidylphenylalanine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 16874-81-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

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