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CAS Number: 179324-69-7
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CAS Number
179324-69-7
PubChem CID
387447
Molecular Formula
C19H25BN4O4
Molecular Weight
384.2 g/mol
Exact Mass
384.196886
InChIKey
GXJABQQUPOEUTA-RDJZCZTQSA-N
IUPAC Name
[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid
SMILES String
B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Bortezomib (CAS 179324-69-7) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C19H25BN4O4 and molecular weight 384. 20 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle, boronic-acid-related structure.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Proteasome Macropain subunit MB1 (Homo sapiens) — 46 assays; Proteasome subunit beta type-8 (Homo sapiens) — 11 assays; 26S proteasome (Homo sapiens) — 6 assays; Proteasome subunit beta type-9 (Homo sapiens) — 5 assays; Proteasome component C5 (Homo sapiens) — 18 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Proteasome Macropain subunit MB1
Homo sapiens · SINGLE PROTEIN · 46 qualifying assays · 31 documents · best pChEMBL 9.3
Experimental evidence source: ChEMBL
Proteasome subunit beta type-8
Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 10 documents · best pChEMBL 8.89
Experimental evidence source: ChEMBL
26S proteasome
Homo sapiens · PROTEIN COMPLEX · 6 qualifying assays · 4 documents · best pChEMBL 8.62
Experimental evidence source: ChEMBL
Proteasome subunit beta type-9
Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 5 documents · best pChEMBL 8.54
Experimental evidence source: ChEMBL
Proteasome component C5
Homo sapiens · SINGLE PROTEIN · 18 qualifying assays · 15 documents · best pChEMBL 7.72
Experimental evidence source: ChEMBL
Safety and handling reference content is available through documentation requests.
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.
Bortezomib is identified by CAS 179324-69-7, with molecular formula C19H25BN4O4, molecular weight 384.2, InChIKey GXJABQQUPOEUTA-RDJZCZTQSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Proteasome Macropain subunit MB1, Proteasome subunit beta type-8, 26S proteasome, Proteasome subunit beta type-9, Proteasome component C5. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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