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Home/Compounds/CAS 1797406-69-9
Formula C49H60ClN9O8S2MW 1002.6Research-use catalog entryCOA/SDS by request

(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

CAS Number: 1797406-69-9

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Loading RDKit molecule structure...
InChIKey: PTAMRJLIOCHJMQ-PYNGZGNASA-NC49H60ClN9O8S2 | MW 1002.6

Chemical Absolute Identifiers

CAS Number

1797406-69-9

PubChem CID

122201421

Molecular Formula

C49H60ClN9O8S2

Molecular Weight

1002.6 g/mol

Exact Mass

1001.36948

InChIKey

PTAMRJLIOCHJMQ-PYNGZGNASA-N

SMILES String

Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCNC(=O)C[C@@H]2N=C(c3ccc(Cl)cc3)c3c(sc(C)c3C)-n3c(C)nnc32)C(C)(C)C)cc1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8. 3. 0.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Bromodomain-containing protein 4 (Homo sapiens) — 13 assays; von Hippel-Lindau disease tumor suppressor (Homo sapiens) — 2 assays; Von Hippel-Lindau disease tumor suppressor/Elongin B/Elongin C (Homo sapiens) — 3 assays; Bromodomain-containing protein 2 (Homo sapiens) — 5 assays; Bromodomain-containing protein 3 (Homo sapiens) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Bromodomain-containing protein 4

Homo sapiens · SINGLE PROTEIN · 13 qualifying assays · 7 documents · best pChEMBL 7.58

Experimental evidence source: ChEMBL

von Hippel-Lindau disease tumor suppressor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.47

Experimental evidence source: ChEMBL

Von Hippel-Lindau disease tumor suppressor/Elongin B/Elongin C

Homo sapiens · PROTEIN COMPLEX · 3 qualifying assays · 2 documents · best pChEMBL 7.16

Experimental evidence source: ChEMBL

Bromodomain-containing protein 2

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 3 documents · best pChEMBL 6.94

Experimental evidence source: ChEMBL

Bromodomain-containing protein 3

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 6.94

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

Names & Synonyms

MZ 1MZ1MZ 1( MZ-1)s8889ethylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID001022548CHEMBL ID: CHEMBL4226570CHEBI ID: CHEBI:189652MZ-1
Literature & Patent References
DOI 10.1021/acsmedchemlett.4c00531Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers.PMID 39967623Use of Aldehyde-Alkyne-Amine Couplings to Generate Medicinal Chemistry-Relevant Linkers.DOI 10.1016/j.ejmech.2023.116062Development of visible-light-activatable photocaged PROTACs.DOI 10.1016/j.ejmech.2024.116901Recent advances in dual PROTACs degrader strategies for disease treatment.DOI 10.1021/acs.jmedchem.3c02123Structure-Guided Design and Optimization of Covalent VHL-Targeted Sulfonyl Fluoride PROTACs.DOI 10.1021/acs.jmedchem.4c01642Closing the Design-Make-Test-Analyze Loop: Interplay between Experiments and Predictions Drives PROTACs Bioavailability.DOI 10.1021/acs.jmedchem.4c01767Design, Synthesis, and Activity Evaluation of BRD4 PROTAC Based on Alkenyl Oxindole-DCAF11 Pair.DOI 10.1021/acsmedchemlett.4c00271Lysineless HiBiT and NanoLuc Tagging Systems as Alternative Tools for Monitoring Targeted Protein Degradation.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

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Text Reference Cues

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Non-public related references

VH032-PEG5-C6-ClCAS 1799506-06-1
Biotin-PEG4-MethyltetrazineCAS 1835759-81-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 1799506-06-1VH032-PEG5-C6-ClCAS 1044870-39-42-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-1H-quinazolin-4-oneCAS 1300031-52-04-[(2s,4r)-1-Acetyl-4-[(4-Chlorophenyl)amino]-2-Methyl-1,2,3,4-Tetrahydroquinolin-6-Yl]benzoic AcidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 1797406-69-9

What are the key identifiers for (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide (CAS 1797406-69-9)?

(2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide is identified by CAS 1797406-69-9, with molecular formula C49H60ClN9O8S2, molecular weight 1002.6, InChIKey PTAMRJLIOCHJMQ-PYNGZGNASA-N.

Does CAS 1797406-69-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Bromodomain-containing protein 4, von Hippel-Lindau disease tumor suppressor, Von Hippel-Lindau disease tumor suppressor/Elongin B/Elongin C, Bromodomain-containing protein 2, Bromodomain-containing protein 3. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 1797406-69-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for (2S,4R)-1-[(2S)-2-[[2-[2-[2-[2-[[2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetyl]amino]ethoxy]ethoxy]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

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