CAS Number: 184036-34-8
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CAS Number
184036-34-8
PubChem CID
216235
Molecular Formula
C18H15ClN2O6S2
Molecular Weight
454.9 g/mol
Exact Mass
454.006006
InChIKey
PHWXUGHIIBDVKD-UHFFFAOYSA-N
IUPAC Name
N-(4-chloro-3-methyl-1,2-oxazol-5-yl)-2-[2-(6-methyl-1,3-benzodioxol-5-yl)acetyl]thiophene-3-sulfonamide
SMILES String
CC1=CC2=C(C=C1CC(=O)C3=C(C=CS3)S(=O)(=O)NC4=C(C(=NO4)C)Cl)OCO2
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Structural features
Sitaxentan (CAS 184036-34-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C18H15ClN2O6S2 and molecular weight 454. 90 g/mol.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.
ChEMBL reports experimental activity evidence for: Endothelin-1 receptor (Homo sapiens) — 6 assays; Bile salt export pump (Homo sapiens) — 2 assays; D(1A) dopamine receptor (Homo sapiens) — 2 assays; Prostaglandin G/H synthase 1 (Homo sapiens) — 2 assays; Thromboxane A2 receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.
Endothelin-1 receptor
Homo sapiens · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 9.37
Experimental evidence source: ChEMBL
Bile salt export pump
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.01
Experimental evidence source: ChEMBL
D(1A) dopamine receptor
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Prostaglandin G/H synthase 1
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
Thromboxane A2 receptor
Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents
Experimental evidence source: ChEMBL
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Preliminary Safety Reference
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Safety Reference / SDS RequestCatalog navigation
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Sitaxentan is identified by CAS 184036-34-8, with molecular formula C18H15ClN2O6S2, molecular weight 454.9, InChIKey PHWXUGHIIBDVKD-UHFFFAOYSA-N.
ChEMBL contains qualifying experimental assay evidence associated with Endothelin-1 receptor, Bile salt export pump, D(1A) dopamine receptor, Prostaglandin G/H synthase 1, Thromboxane A2 receptor. These records do not establish therapeutic efficacy or clinical use.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
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