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Home/Compounds/CAS 185991-24-6
Formula C24H38N6MW 410.6Research-use catalog entryCOA/SDS by request

Amd-8664

CAS Number: 185991-24-6

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Available Options

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Loading RDKit molecule structure...
InChIKey: CWJJHESJXJQCJA-UHFFFAOYSA-NC24H38N6 | MW 410.6

Chemical Absolute Identifiers

CAS Number

185991-24-6

PubChem CID

483559

Molecular Formula

C24H38N6

Molecular Weight

410.6 g/mol

Exact Mass

410.315795

InChIKey

CWJJHESJXJQCJA-UHFFFAOYSA-N

IUPAC Name

N-(pyridin-2-ylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamine

SMILES String

C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CNCC3=CC=CC=N3

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Amd-8664 (CAS 185991-24-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C24H38N6 and molecular weight 410. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: C-X-C chemokine receptor type 4 (Homo sapiens) — 41 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

C-X-C chemokine receptor type 4

Homo sapiens · SINGLE PROTEIN · 41 qualifying assays · 4 documents · best pChEMBL 8.06

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Amd-8664

Names & Synonyms

2-Pyridinemethanamine, N-((4-(1,4,8,11-tetraazacyclotetradec-1-ylmethyl)phenyl)methyl)-AMD 8664AMD 3465N-(4-((1,4,8,11-tetraazacyclotetradecan-1-yl)methyl)benzyl)-1-(pyridin-2-yl)methanaminerac Methamphetamine-d3 Hydrochloride
Show all synonyms
AMD3465 (*Hexahydrobromide*)AMD 3465 (*Hexahydrobromide*)AMD-3465 (*Hexahydrobromide*)N-(2-pyridylmethyl)-1-[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methanamineN-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanaminePyridin-2-ylmethyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmethyl)-benzyl]-amineN-[1,4,8,11-Tetraazacyclotetradecanyl-1,4-phenylenebis(methylene)]-2-(amino-methyl)pyridine
External Identifiers
CHEMBL ID: CHEMBL477121UNII: IMD9Z48ZTTHMDB ID: HMDB0248283WIKIDATA ID: Q27280798
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116594Development and therapeutic perspectives of CXCR4 antagonists for disease therapy.PMID 38879970Development and therapeutic perspectives of CXCR4 antagonists for disease therapy.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.ejmech.2018.02.043The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential.PMID 29500940The chemical diversity and structure-based evolution of non-peptide CXCR4 antagonists with diverse therapeutic potential.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

AMD 3465 hexahydrobromideCAS 185991-07-5
N-(5-bromo-2-pyridinyl)-N'-(2-pyridin-2-ylethyl)carbamimidothioic acidCAS 149488-17-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 185991-07-5AMD 3465 hexahydrobromideCAS 55778-02-4WZ 811CAS 217645-70-0BX-471 free baseCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 185991-24-6

What are the key identifiers for Amd-8664 (CAS 185991-24-6)?

Amd-8664 is identified by CAS 185991-24-6, with molecular formula C24H38N6, molecular weight 410.6, InChIKey CWJJHESJXJQCJA-UHFFFAOYSA-N.

Does CAS 185991-24-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with C-X-C chemokine receptor type 4, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 185991-24-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Amd-8664?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 185991-24-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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