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Home/Compounds/CAS 186953-56-0
Formula C20H20N4O3MW 364.4Research-use catalog entryCOA/SDS by request

Pafuramidine

CAS Number: 186953-56-0

Sourcing & RFQ

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Available options

Available Options

Package
1 mg
Purity
98%
Price
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Package
10 mg
Purity
98%
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Package
5 mg
Purity
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Loading RDKit molecule structure...
InChIKey: UKOQVLAXCBRRGH-UHFFFAOYSA-NC20H20N4O3 | MW 364.4

Chemical Absolute Identifiers

CAS Number

186953-56-0

PubChem CID

5480200

Molecular Formula

C20H20N4O3

Molecular Weight

364.4 g/mol

Exact Mass

364.153541

InChIKey

UKOQVLAXCBRRGH-UHFFFAOYSA-N

IUPAC Name

N'-methoxy-4-[5-[4-[(Z)-N'-methoxycarbamimidoyl]phenyl]furan-2-yl]benzenecarboximidamide

SMILES String

CO/N=C(\N)/C1=CC=C(C=C1)C2=CC=C(O2)C3=CC=C(C=C3)/C(=N/OC)/N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pafuramidine (CAS 186953-56-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C20H20N4O3 and molecular weight 364. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pafuramidine

Names & Synonyms

pafuramidinaDB289 cpdpafuramidinumN'-methoxy-4-(5-(4-((Z)-N'-methoxycarbamimidoyl)phenyl)furan-2-yl)benzenecarboximidamideN-methoxy-4-(5-(4-(N-methoxycarbamimidoyl)phenyl)furan-2-yl)benzene-1-carboximidamide
Show all synonyms
Pafuramidine [INN]N'-methoxy-4-[5-[4-(N'-methoxycarbamimidoyl)phenyl]furan-2-yl]benzenecarboximidamide4,4'-(FURAN-2,5-DIYL)BIS(N-METHOXYBENZENECARBOXIMIDAMIDE)BENZENECARBOXIMIDAMIDE, 4,4'-(2,5-FURANDIYL)BIS(N-METHOXY-
External Identifiers
CHEMBL ID: CHEMBL319669UNII: H1VG379J2XDRUGBANK ID: DB06532HMDB ID: HMDB0244823METABOLOMICS WORKBENCH ID: 149823NCI THESAURUS CODE: C81542
Literature & Patent References
DOI 10.1016/j.bmcl.2024.129931Inhibitors of Rickettsia prowazekii methionine aminopeptidase 1 identified from the Pandemic Response Box.PMID 39154713Inhibitors of Rickettsia prowazekii methionine aminopeptidase 1 identified from the Pandemic Response Box.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1016/j.ejmech.2016.12.041Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum.PMID 28038325Synthesis, biological characterisation and structure activity relationships of aromatic bisamidines active against Plasmodium falciparum.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

PentamidineCAS 100-33-4
Pentamidine dihydrochlorideCAS 50357-45-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 100-88-9CyclamateCAS 1000787-75-6TegobuvirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 186953-56-0

What are the key identifiers for Pafuramidine (CAS 186953-56-0)?

Pafuramidine is identified by CAS 186953-56-0, with molecular formula C20H20N4O3, molecular weight 364.4, InChIKey UKOQVLAXCBRRGH-UHFFFAOYSA-N.

Does CAS 186953-56-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 186953-56-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pafuramidine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 186953-56-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.