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Home/Compounds/CAS 19057-60-4
Formula C45H72O16MW 869Research-use catalog entryCOA/SDS by request

(+)-Dioscin

CAS Number: 19057-60-4

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Loading RDKit molecule structure...
InChIKey: VNONINPVFQTJOC-ZGXDEBHDSA-NC45H72O16 | MW 869

Chemical Absolute Identifiers

CAS Number

19057-60-4

PubChem CID

119245

Molecular Formula

C45H72O16

Molecular Weight

869 g/mol

Exact Mass

868.482036

InChIKey

VNONINPVFQTJOC-ZGXDEBHDSA-N

IUPAC Name

(2S,3R,4R,5R,6S)-2-[(2R,3S,4S,5R,6R)-4-hydroxy-2-(hydroxymethyl)-6-[(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,16S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-16-yl]oxy-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-6-methyloxane-3,4,5-triol

SMILES String

C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5(CC[C@@H](C6)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)O[C@H]8[C@@H]([C@@H]([C@H]([C@@H](O8)C)O)O)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O)O)C)C)C)OC1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

(+)-Dioscin (CAS 19057-60-4) is listed in the Advanced Chemicals portfolio, with molecular formula C45H72O16 and molecular weight 869. 00 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Solute carrier organic anion transporter family member 1B3 (Homo sapiens) — 5 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Solute carrier organic anion transporter family member 1B3

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 1 documents · best pChEMBL 5.99

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

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PPE

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Disposal

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Fire Fighting

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Accidental Release

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

(+)-Dioscin

Names & Synonyms

Dioscin3-O-[alpha-L-Rha-(1->4)-[alpha-L-Rha-(1->2)]-beta-D-Glc]-diosgenin(25R)-spirost-5-en-3beta-yl alpha-L-rhamnopyranosyl-(1->2)-[alpha-L-mannopyranosyl-(1->4)]-beta-D-glucopyranoside3-O-(alpha-L-Rha-(1->4)-(alpha-L-Rha-(1->2))-beta-D-Glc)-diosgenin(25R)-spirost-5-en-3beta-yl alpha-L-rhamnopyranosyl-(1->2)-(alpha-L-mannopyranosyl-(1->4))-beta-D-glucopyranoside
Show all synonyms
Collettiside IIICCRIS 4123PARIS III3-O-(Rhaalpha1-4(Rhaalpha1-2)Glcbeta)-(25R)-spirost-5-en-3beta-ol3-O-[alpha-L-Rhap-(1->4)-[alpha-L-Rhap-(1->2)]-beta-D-Glcp]-diosgeninCollettinside IIIDioscin?Polyphyllin?Iii?DIOSCIN [MI]DIOSCIN [WHO-DD]Dioscin (Collettiside III)Dioscin, >=95% (HPLC)s2379Diosgenin bis-alpha-L-rhamnopyranosyl)-(1-2 and 1-4)-beta-D-glucopyranoside(25r)-3beta-[2-O,4-O-bis(alpha-l-rhamnopyranosyl)-beta-d-glucopyranosyloxy]spirosta-5-ene
External Identifiers
EC NUMBER: 866-819-8CHEMBL ID: CHEMBL507001CHEBI ID: CHEBI:74023UNII: 3B95U4OLWVKEGG ID: C08897METABOLOMICS WORKBENCH ID: 52716NCI THESAURUS CODE: C221959WIKIDATA ID: Q5807682
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116915Plant based steroidal and triterpenoid sapogenins: Chemistry on diosgenin and biological aspects.PMID 39366126Plant based steroidal and triterpenoid sapogenins: Chemistry on diosgenin and biological aspects.DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.1016/j.ejmech.2020.113068Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.DOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsPMID 33310292Structures/cytotoxicity/selectivity relationship of natural steroidal saponins against GSCs and primary mechanism of tribulosaponin A.DOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effort

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

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What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
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  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

TrillinCAS 14144-06-0
TomatineCAS 17406-45-0
(+)-MelezitoseCAS 597-12-6
DidyminCAS 14259-47-3
TobramycinCAS 32986-56-4

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 14144-06-0TrillinCAS 17406-45-0TomatineCAS 134523-00-5AtorvastatinCAS 169590-42-5CelecoxibCAS 61-78-9p-Aminohippuric acidCAS 100-88-9CyclamateCAS 1000787-75-6TegobuvirCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 19057-60-4

What are the key identifiers for (+)-Dioscin (CAS 19057-60-4)?

(+)-Dioscin is identified by CAS 19057-60-4, with molecular formula C45H72O16, molecular weight 869, InChIKey VNONINPVFQTJOC-ZGXDEBHDSA-N.

Does CAS 19057-60-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Solute carrier organic anion transporter family member 1B3, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 19057-60-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for (+)-Dioscin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 19057-60-4 available for quotation?

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