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Home/Compounds/CAS 19171-19-8
Formula C13H11N3O4MW 273.24Research-use catalog entryCOA/SDS by request

Pomalidomide

CAS Number: 19171-19-8

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Loading RDKit molecule structure...
InChIKey: UVSMNLNDYGZFPF-UHFFFAOYSA-NC13H11N3O4 | MW 273.24

Chemical Absolute Identifiers

CAS Number

19171-19-8

PubChem CID

134780

Molecular Formula

C13H11N3O4

Molecular Weight

273.24 g/mol

Exact Mass

273.074956

InChIKey

UVSMNLNDYGZFPF-UHFFFAOYSA-N

IUPAC Name

4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

SMILES String

C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)N

Physical Properties

Water Solubility

0.01 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Pomalidomide (CAS 19171-19-8) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C13H11N3O4 and molecular weight 273. 24 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Zinc finger protein Aiolos (Homo sapiens) — 5 assays; Cereblon/Ikaros (Homo sapiens) — 7 assays; DNA-binding protein Ikaros (Homo sapiens) — 5 assays; Protein cereblon (Homo sapiens) — 12 assays; Thromboxane A2 receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Zinc finger protein Aiolos

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 4 documents · best pChEMBL 7.7

Experimental evidence source: ChEMBL

Cereblon/Ikaros

Homo sapiens · PROTEIN COMPLEX · 7 qualifying assays · 5 documents · best pChEMBL 7.62

Experimental evidence source: ChEMBL

DNA-binding protein Ikaros

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 3 documents · best pChEMBL 7.3

Experimental evidence source: ChEMBL

Protein cereblon

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 9 documents · best pChEMBL 7.08

Experimental evidence source: ChEMBL

Thromboxane A2 receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.57

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Pomalidomide

Names & Synonyms

ActimidPomalystImnovid4-Aminothalidomide4-Amino-2-(2,6-dioxo-3-piperidyl)isoindoline-1,3-dione
Show all synonyms
1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimideIMiD 3CC 4047IMiD3Pomalidomida4-amino-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dionePhthalimide, 3-amino-N-(2,6-dioxo-3-piperidyl)-pomalidomidum4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione4-Amino-2-(2,6-dioxo-3-piperidinyl)isoindole-1,3-diones15674-amino-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dionePomalidomide [USAN:INN]
External Identifiers
EC NUMBER: 805-902-5DSSTOX SUBSTANCE ID: DTXSID40893458CHEMBL ID: CHEMBL43452CHEBI ID: CHEBI:72690UNII: D2UX06XLB5DRUGBANK ID: DB08910DRUGBANK ID: DB17419HMDB ID: HMDB0256694KEGG ID: D08976METABOLOMICS WORKBENCH ID: 66067NCI THESAURUS CODE: C72560PHARMGKB ID: PA166428902RXCUI: 1369713WIKIDATA ID: Q7227206
Literature & Patent References
DOI 10.1016/j.ejmech.2024.117016Discovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2.DOI 10.1021/acs.jmedchem.4c02205Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer.DOI 10.1021/acs.jmedchem.5c00428Discovery and Characterization of RP03707: A Highly Potent and Selective KRAS<sup>G12D</sup> PROTAC.PMID 39520729Discovery of the first selective and potent PROTAC degrader for the pseudokinase TRIB2.PMID 39746330Discovery of a Potent and Selective GSPT1 Molecular Glue Degrader for the Treatment of Castration-Resistant Prostate Cancer.PMID 40338735Discovery and Characterization of RP03707: A Highly Potent and Selective KRAS<sup>G12D</sup> PROTAC.DOI 10.1016/j.bmc.2024.117673Fluorescent probes and degraders of the sterol transport protein Aster-A.DOI 10.1016/j.bmc.2024.117867Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4-NitrothalidomideCAS 19171-18-7
3-Aminopiperidine-2,6-dione hydrochlorideCAS 24666-56-6
3-NitrophthalimideCAS 603-62-3
4-Nitro-N-carboethoxyphthalimideCAS 190910-88-4
1,2-Benzenedicarboxylic acid, 3-amino-, hydrochloride (1:1)CAS 6946-22-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 19171-18-74-NitrothalidomideCAS 24666-56-63-Aminopiperidine-2,6-dione hydrochlorideCAS 50-35-1ThalidomideCAS 191732-72-6LenalidomideCAS 128517-07-7RomidepsinCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 19171-19-8

What are the key identifiers for Pomalidomide (CAS 19171-19-8)?

Pomalidomide is identified by CAS 19171-19-8, with molecular formula C13H11N3O4, molecular weight 273.24, InChIKey UVSMNLNDYGZFPF-UHFFFAOYSA-N.

Does CAS 19171-19-8 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Zinc finger protein Aiolos, Cereblon/Ikaros, DNA-binding protein Ikaros, Protein cereblon, Thromboxane A2 receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 19171-19-8?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Pomalidomide?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 19171-19-8 available for quotation?

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