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Home/Compounds/CAS 198821-22-6
Formula C23H24N4O6MW 452.5Research-use catalog entryCOA/SDS by request

Merimepodib

CAS Number: 198821-22-6

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Loading RDKit molecule structure...
InChIKey: JBPUGFODGPKTDW-SFHVURJKSA-NC23H24N4O6 | MW 452.5

Chemical Absolute Identifiers

CAS Number

198821-22-6

PubChem CID

153241

Molecular Formula

C23H24N4O6

Molecular Weight

452.5 g/mol

Exact Mass

452.169585

InChIKey

JBPUGFODGPKTDW-SFHVURJKSA-N

IUPAC Name

[(3S)-oxolan-3-yl] N-[[3-[[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoylamino]phenyl]methyl]carbamate

SMILES String

COC1=C(C=CC(=C1)NC(=O)NC2=CC=CC(=C2)CNC(=O)O[C@H]3CCOC3)C4=CN=CO4

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Merimepodib (CAS 198821-22-6) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C23H24N4O6 and molecular weight 452. 50 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Inosine-5'-monophosphate dehydrogenase 2 (Homo sapiens) — 3 assays; Protein deacetylase HDAC6 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Inosine-5'-monophosphate dehydrogenase 2

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8

Experimental evidence source: ChEMBL

Protein deacetylase HDAC6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Merimepodib

Names & Synonyms

MMPDVI-21,497Carbamic acid, ((3-((((3-methoxy-4-(5-oxazolyl)phenyl)amino)carbonyl)amino)phenyl)methyl)-, (3S)-tetrahydro-3-furanyl ester(3S)-oxolan-3-yl N-{[3-({[3-methoxy-4-(1,3-oxazol-5-yl)phenyl]carbamoyl}amino)phenyl]methyl}carbamate(3S)-oxolan-3-yl N-((3-(((3-methoxy-4-(1,3-oxazol-5-yl)phenyl)carbamoyl)amino)phenyl)methyl)carbamate
Show all synonyms
carbamic acid, [[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl esterMERIMEPODIBUMCarbamic acid, N-[[3-[[[[3-methoxy-4-(5-oxazolyl)phenyl]amino]carbonyl]amino]phenyl]methyl]-, (3S)-tetrahydro-3-furanyl ester(S)-tetrahydrofuran-3-yl 3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzylcarbamate[(3S)-tetrahydrofuran-3-yl] N-[[3-[(3-methoxy-4-oxazol-5-yl-phenyl)carbamoylamino]phenyl]methyl]carbamate(S)-Tetrahydro-3-furyl (m-(3-(3-methoxy-4-(5-oxazolyl)phenyl)ureido)benzyl)carbamate(S)-tetrahydrofuran-3-yl (3-(3-(3-methoxy-4-(oxazol-5-yl)phenyl)ureido)benzyl)carbamateVx 497Merimepodib [USAN:INN]MerimebodibVX497Merimepodib [USAN]Merimepodib(VX-497)MERIMEPODIB [MI]
External Identifiers
DSSTOX SUBSTANCE ID: DTXSID70173639CHEMBL ID: CHEMBL304087UNII: 2ZL2BA06FUDRUGBANK ID: DB04862KEGG ID: D04936METABOLOMICS WORKBENCH ID: 149292NCI THESAURUS CODE: C66097PHARMGKB ID: PA166210763WIKIDATA ID: Q1727082
Literature & Patent References
DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.1021/acs.jmedchem.9b00775Drugs for the Treatment of Zika Virus Infection.DOI 10.1038/s41586-020-2286-9A SARS-CoV-2 protein interaction map reveals targets for drug repurposingDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortPMID 31549836Drugs for the Treatment of Zika Virus Infection.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 198821-79-33-Methoxy-4-(oxazol-5-yl)anilineCAS 24280-93-1Mycophenolic AcidCAS 100-88-9CyclamateCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 198821-22-6

What are the key identifiers for Merimepodib (CAS 198821-22-6)?

Merimepodib is identified by CAS 198821-22-6, with molecular formula C23H24N4O6, molecular weight 452.5, InChIKey JBPUGFODGPKTDW-SFHVURJKSA-N.

Does CAS 198821-22-6 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Inosine-5'-monophosphate dehydrogenase 2, Protein deacetylase HDAC6. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 198821-22-6?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Merimepodib?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 198821-22-6 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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