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Home/Compounds/CAS 19916-73-5
Formula C12H11N5OMW 241.25Research-use catalog entryCOA/SDS by request

6-(Phenylmethoxy)-9H-purin-2-amine

CAS Number: 19916-73-5

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Loading RDKit molecule structure...
InChIKey: KRWMERLEINMZFT-UHFFFAOYSA-NC12H11N5O | MW 241.25

Chemical Absolute Identifiers

CAS Number

19916-73-5

PubChem CID

4578

Molecular Formula

C12H11N5O

Molecular Weight

241.25 g/mol

Exact Mass

241.09636

InChIKey

KRWMERLEINMZFT-UHFFFAOYSA-N

IUPAC Name

6-phenylmethoxy-7H-purin-2-amine

SMILES String

C1=CC=C(C=C1)COC2=NC(=NC3=C2NC=N3)N

Physical Properties

Water Solubility

35.9 mol/L

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

6-(Phenylmethoxy)-9H-purin-2-amine (CAS 19916-73-5) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C12H11N5O and molecular weight 241. 25 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: RecQ-like DNA helicase BLM (Homo sapiens) — 2 assays; Methylated-DNA--protein-cysteine methyltransferase (Homo sapiens) — 29 assays; Cytochrome P450 2D6 (Homo sapiens) — 2 assays; Nuclear factor NF-kappa-B p105 subunit (Homo sapiens) — 2 assays; Cytochrome P450 2C19 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

RecQ-like DNA helicase BLM

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 7.8

Experimental evidence source: ChEMBL

Methylated-DNA--protein-cysteine methyltransferase

Homo sapiens · SINGLE PROTEIN · 29 qualifying assays · 11 documents · best pChEMBL 7.41

Experimental evidence source: ChEMBL

Cytochrome P450 2D6

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 6.3

Experimental evidence source: ChEMBL

Nuclear factor NF-kappa-B p105 subunit

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.25

Experimental evidence source: ChEMBL

Cytochrome P450 2C19

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.2

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

6-(Phenylmethoxy)-9H-purin-2-amine

Names & Synonyms

o6-benzylguanine6-O-BenzylguanineO(6)-Benzylguanine2-Amino-6-(benzyloxy)purineO(6)-Bgua
Show all synonyms
2-Amino-6-(phenylmethoxy)-9H-purine6-(Benzyloxy)-7H-purin-2-amine6-(benzyloxy)-9H-purin-2-amine2-amino-6-benzyloxypurine6-Benzyloxyguanine9H-Purin-2-amine, 6-(phenylmethoxy)-O-6-Benzylguanine1H-Purin-2-amine, 6-(phenylmethoxy)-6-benzyloxy-7H-purin-2-amine6-(Benzyloxy)guanine6-(Phenylmethoxy)-1H-purin-2-amineO6-BG6-(benzyloxy)-1H-purin-2-aminePurine, 2-amino-6-(benzyloxy)-
External Identifiers
EC NUMBER: 449-870-7EC NUMBER: 633-744-5DSSTOX SUBSTANCE ID: DTXSID20173700CHEMBL ID: CHEMBL407874UNII: 01KC87F8FEDRUGBANK ID: DB11919HMDB ID: HMDB0255878METABOLOMICS WORKBENCH ID: 152998NCI THESAURUS CODE: C1306WIKIDATA ID: Q7072275
Experimental Spectrum References
13C NMR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c02144Structure-Guided Optimization and Preclinical Evaluation of 6-&lt;i&gt;O&lt;/i&gt;-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.PMID 39868498Structure-Guided Optimization and Preclinical Evaluation of 6-&lt;i&gt;O&lt;/i&gt;-Benzylguanine-Based Pin1 Inhibitor for Hepatocellular Carcinoma Treatment.DOI 10.1016/j.ejmech.2021.113909Acridine-O<sup>6</sup>-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.PMID 34731767Acridine-O<sup>6</sup>-benzylguanine hybrids: Synthesis, DNA binding, MGMT inhibition and antiproliferative activity.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.6019/CHEMBL4808148HDAC6 screening dataset using tau-based substrate in an enzymatic assay yields selective inhibitors and activatorsDOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screen

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

3-(Benzyloxy)-2-methylpyridin-4(1H)-oneCAS 61160-18-7
3-(Benzyloxy)-5-bromo-2-methyl-4-pyridinolCAS 906657-86-1
3-Benzyloxy-2-methyl-4-pyroneCAS 61049-69-2
3-(Benzyloxy)-4-oxo-4h-pyran-2-carboxylic acidCAS 119736-16-2
3-(Benzyloxy)propane-1,2-diolCAS 17325-85-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 21829-25-4NifedipineCAS 23593-75-1ClotrimazoleCAS 26049-94-5(3S)-3-Benzyloxycarbonylamino-1-chloro-4-phenyl-2-butanoneCAS 100643-71-8DesloratadineCAS 10083-24-6PiceatannolCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 19916-73-5

What are the key identifiers for 6-(Phenylmethoxy)-9H-purin-2-amine (CAS 19916-73-5)?

6-(Phenylmethoxy)-9H-purin-2-amine is identified by CAS 19916-73-5, with molecular formula C12H11N5O, molecular weight 241.25, InChIKey KRWMERLEINMZFT-UHFFFAOYSA-N.

Does CAS 19916-73-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with RecQ-like DNA helicase BLM, Methylated-DNA--protein-cysteine methyltransferase, Cytochrome P450 2D6, Nuclear factor NF-kappa-B p105 subunit, Cytochrome P450 2C19. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 19916-73-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 6-(Phenylmethoxy)-9H-purin-2-amine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 19916-73-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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