Chemical Identity
Molecular Formula
C6H4BClF3NO2
Molecular Weight
225.36 g/mol
Exact Mass
224.997571
PubChem CID
21865043
IUPAC Name
[2-chloro-6-(trifluoromethyl)-3-pyridinyl]boronic acid
SMILES String
OB(O)c1ccc(C(F)(F)F)nc1Cl
Names & Synonyms
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External Identifiers
Catalog Overview
(2-Chloro-6-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 205240-63-7, is a highly functionalized pyridine derivative. It contains a boronic acid group, a chlorine atom, and a trifluoromethyl group attached to a pyridine ring. With a molecular formula of C6H4BClF3NO2 and a molecular weight of 225. 36, this compound serves as a key intermediate in synthetic organic chemistry.
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
(2-Chloro-6-(trifluoromethyl)pyridin-3-yl)boronic acid, identified by CAS 205240-63-7, is a highly functionalized pyridine derivative. It contains a boronic acid group, a chlorine atom, and a trifluoromethyl group attached to a pyridine ring. With a molecular formula of C6H4BClF3NO2 and a molecular weight of 225.36, this compound serves as a key intermediate in synthetic organic chemistry. Its boronic acid functionality makes it particularly useful in Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds with aryl halides or triflates. The presence of the chloro and trifluoromethyl groups provides opportunities for further functionalization and introduces specific electronic and steric properties, making it valuable for synthesizing novel pharmaceutical candidates, agrochemicals, and materials in research and development.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
white solid
Physical State
solid
Melting Point
209.0 °C
Boiling Point
294.0 °C
Density
1.65 g/cm³
Water Solubility
0.224 mol/L
Flash Point
251.5 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- For research use only. Handle with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or under a fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Store in a cool, dry place, away from incompatible materials. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures.
Related Products / Graph Discovery
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