Chemical Identity
Molecular Formula
C12H14BClF3NO2
Molecular Weight
307.5 g/mol
Exact Mass
307.075821
PubChem CID
72221287
SMILES String
CC1(C)OB(c2ccc(C(F)(F)F)nc2Cl)OC1(C)C
Names & Synonyms
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External Identifiers
Catalog Overview
2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine, with CAS 2068737-11-9, is a valuable research chemical characterized by a pyridine core substituted with a chlorine atom, a trifluoromethyl group, and a pinacol boronic ester. The presence of the boronic ester makes it an excellent reagent for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The chloro and trifluoromethyl groups provide opportunities for further functionalization or introduce specific electronic and steric properties, making this compound a key intermediate in the synthesis of complex...
Use Context
- Research chemical sourcing
- Custom synthesis and catalog availability review
- COA, SDS, pricing, and fulfillment workflow
Read more catalog context
2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine, with CAS 2068737-11-9, is a valuable research chemical characterized by a pyridine core substituted with a chlorine atom, a trifluoromethyl group, and a pinacol boronic ester. The presence of the boronic ester makes it an excellent reagent for Suzuki-Miyaura cross-coupling reactions, enabling the formation of new carbon-carbon bonds. The chloro and trifluoromethyl groups provide opportunities for further functionalization or introduce specific electronic and steric properties, making this compound a key intermediate in the synthesis of complex organic molecules, including potential pharmaceutical and agrochemical candidates, for research purposes only.
Physical Data
EstimatedEstimated / predicted physical property values for catalog reference.
Appearance
White to off-white crystalline powder
Physical State
Solid
Melting Point
85.0 °C
Boiling Point
280.0 °C
Density
1.4 g/cm³
Water Solubility
Slightly soluble
Flash Point
135.0 °C
Applications / Classifications
Biological Target Reference
No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.
Preliminary Safety-Style Reference
PreliminaryPreliminary safety-style information for reference only. Not a supplier SDS.
Handling and Storage
- Handle 2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-6-(trifluoromethyl)pyridine with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or a chemical fume hood to avoid inhalation. Prevent skin and eye contact, and do not ingest. Always consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place away from incompatible materials.
Related Products / Graph Discovery
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