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Home/Compounds/CAS 209467-52-7
Formula C20H22N8O6S2MW 534.6Research-use catalog entryCOA/SDS by request

Ceftobiprole

CAS Number: 209467-52-7

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Loading RDKit molecule structure...
InChIKey: VOAZJEPQLGBXGO-SDAWRPRTSA-NC20H22N8O6S2 | MW 534.6

Chemical Absolute Identifiers

CAS Number

209467-52-7

PubChem CID

135413542

Molecular Formula

C20H22N8O6S2

Molecular Weight

534.6 g/mol

Exact Mass

534.110373

InChIKey

VOAZJEPQLGBXGO-SDAWRPRTSA-N

IUPAC Name

(6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-hydroxyiminoacetyl]amino]-8-oxo-3-[(E)-[2-oxo-1-[(3R)-pyrrolidin-3-yl]pyrrolidin-3-ylidene]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

SMILES String

Nc1nc(/C(=N/O)C(=O)N[C@@H]2C(=O)N3C(C(=O)O)=C(/C=C4\CCN([C@@H]5CCNC5)C4=O)CS[C@H]23)ns1

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Ceftobiprole (CAS 209467-52-7) is listed in the Advanced Chemicals portfolio, with molecular formula C20H22N8O6S2 and molecular weight 534. 60 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: MecA (Staphylococcus aureus) — 6 assays; Beta-lactamase (Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228)) — 16 assays; Beta-lactamase (Enterobacter cloacae) — 12 assays; Penicillin-binding protein 2B (Streptococcus pneumoniae (strain ATCC BAA-255 / R6)) — 5 assays; Beta-lactamase (Staphylococcus aureus) — 4 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

MecA

Staphylococcus aureus · SINGLE PROTEIN · 6 qualifying assays · 3 documents · best pChEMBL 5.72

Experimental evidence source: ChEMBL

Beta-lactamase

Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228) · SINGLE PROTEIN · 16 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Beta-lactamase

Enterobacter cloacae · SINGLE PROTEIN · 12 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Penicillin-binding protein 2B

Streptococcus pneumoniae (strain ATCC BAA-255 / R6) · SINGLE PROTEIN · 5 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Beta-lactamase

Staphylococcus aureus · SINGLE PROTEIN · 4 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Ceftobiprole

Names & Synonyms

ceftobiprolceftobiprolumRo 63-9141BAL 9141Zeftera
Show all synonyms
CEFTOBIPROLE [MI]Ceftobiprole (USAN/INN)CEFTOBIPROLE [INN]Ceftobiprole [USAN:INN]Ro-63-9141/000CEFTOBIPROLE [USAN]CEFTOBIPROLE [WHO-DD]BAL 9141-0005-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID, 7-(((2Z)-(5-AMINO-1,2,4-THIADIAZOL-3-YL)(HYDROXYIMINO)ACETYL)AMINO)-8-OXO-3-((E)-((3'R)-2-7-{[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino}-3-{(E)-[(3'R)-2-oxo[1,3'-bipyrrolidin]-3-ylidene]methyl}-3,4-didehydrocepham-4-carboxylic acid
External Identifiers
EC NUMBER: 606-675-3DSSTOX SUBSTANCE ID: DTXSID40870229CHEMBL ID: CHEMBL520642CHEBI ID: CHEBI:140407UNII: 5T97333YZKDRUGBANK ID: DB04918KEGG ID: D08885METABOLOMICS WORKBENCH ID: 149335NCI THESAURUS CODE: C65306RXCUI: 2691333Ro-63-9141Ro-639141
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c00983Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.PMID 39083648Interaction of Cephalosporins with Human Serum Albumin: A Structural Study.DOI 10.1016/j.ejmech.2020.112312Penicillin binding protein 2a: An overview and a medicinal chemistry perspective.PMID 32442851Penicillin binding protein 2a: An overview and a medicinal chemistry perspective.DOI 10.1128/aac.00011-10KPC-producing extreme drug-resistant Klebsiella pneumoniae isolate from a patient with diabetes mellitus and chronic renal failure on hemodialysis in South Korea.DOI 10.1128/aac.00060-10Differential selection of single-step AmpC or efflux mutants of Pseudomonas aeruginosa by using cefepime, ceftazidime, or ceftobiprole.DOI 10.1128/aac.00572-10Synthesis and spectrum of the neoglycoside ACHN-490.DOI 10.1128/aac.00590-10Affinity of ceftobiprole for penicillin-binding protein 2b in Streptococcus pneumoniae strains with various susceptibilities to penicillin.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

7-[[2-Ethoxyimino-2-[5-(phosphonoamino)-1,2,4-thiadiazol-3-yl]acetyl]amino]-3-[[4-(1-methylpyridin-1-ium-4-yl)-1,3-thiazol-2-yl]sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid acetateCAS 400827-46-5
(2Z)-(5-amino-1,2,4-thiadiazol-3-yl)(ethoxyimino)acetic acidCAS 75028-24-9
(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-methyl-1-((2-methylpropan-2-yl)oxy)-1-oxopropan-2-yl)oxyiminoacetic acidCAS 76028-96-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 89786-04-9TazobactamCAS 61477-96-1PiperacillinCAS 68373-14-8SulbactamCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 209467-52-7

What are the key identifiers for Ceftobiprole (CAS 209467-52-7)?

Ceftobiprole is identified by CAS 209467-52-7, with molecular formula C20H22N8O6S2, molecular weight 534.6, InChIKey VOAZJEPQLGBXGO-SDAWRPRTSA-N.

Does CAS 209467-52-7 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with MecA, Beta-lactamase, Beta-lactamase, Penicillin-binding protein 2B, Beta-lactamase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 209467-52-7?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Ceftobiprole?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 209467-52-7 available for quotation?

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