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Home/Compounds/CAS 212142-18-2
Formula C24H21ClN4O4MW 464.9Research-use catalog entryCOA/SDS by request

Vatalanib Succinate

CAS Number: 212142-18-2

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Loading RDKit molecule structure...
InChIKey: LLDWLPRYLVPDTG-UHFFFAOYSA-NC24H21ClN4O4 | MW 464.9

Chemical Absolute Identifiers

CAS Number

212142-18-2

PubChem CID

151193

Molecular Formula

C24H21ClN4O4

Molecular Weight

464.9 g/mol

Exact Mass

464.125133

InChIKey

LLDWLPRYLVPDTG-UHFFFAOYSA-N

IUPAC Name

butanedioic acid;N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine

SMILES String

C1=CC=C2C(=C1)C(=NN=C2NC3=CC=C(C=C3)Cl)CC4=CC=NC=C4.C(CC(=O)O)C(=O)O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Vatalanib Succinate (CAS 212142-18-2) is listed in the Advanced Chemicals portfolio, with molecular formula C24H21ClN4O4 and molecular weight 464. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Vascular endothelial growth factor receptor 2 (Homo sapiens) — 9 assays; Vascular endothelial growth factor receptor 3 (Homo sapiens) — 2 assays; Vascular endothelial growth factor receptor 1 (Homo sapiens) — 3 assays; Platelet-derived growth factor receptor beta (Homo sapiens) — 2 assays; Mast/stem cell growth factor receptor Kit (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Vascular endothelial growth factor receptor 2

Homo sapiens · SINGLE PROTEIN · 9 qualifying assays · 5 documents · best pChEMBL 7.8

Experimental evidence source: ChEMBL

Vascular endothelial growth factor receptor 3

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 7.19

Experimental evidence source: ChEMBL

Vascular endothelial growth factor receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 7.11

Experimental evidence source: ChEMBL

Platelet-derived growth factor receptor beta

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.31

Experimental evidence source: ChEMBL

Mast/stem cell growth factor receptor Kit

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.21

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Vatalanib Succinate

Names & Synonyms

PTK787/ZK222584CGP 79787DPtk 787ZK 222584PTK 787/ZK 222584
Show all synonyms
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, butanedioate (1:1)PTK-787/ZK-2225841-(4-chloroanilino)-4-(4-pyridylmethyl)phthalazine succinate1-[4-Chloroanilino]-4-[4-pyridylmethyl]phthalazine SuccinateN-(4-Chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine succinateC24H21ClN4O4Vatalanib (succinate)VatalanibsuccinatePTK/ZKvatalanib monosuccinateVATALANIB SUCCINATE [MI]VATALANIB SUCCINATE [WHO-DD]butanedioic acid,N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amineN-(4-Chlorophenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine butanedioate1-Phthalazinamine, butanedioate (1:1)
External Identifiers
EC NUMBER: 658-085-0DSSTOX SUBSTANCE ID: DTXSID60175445CHEMBL ID: CHEMBL75232CHEBI ID: CHEBI:90623UNII: V5FUB77031NCI THESAURUS CODE: C74945
Literature & Patent References
DOI 10.21203/rs.3.rs-23951/v1Identification of inhibitors of SARS-CoV-2 in-vitro cellular toxicity in human (Caco-2) cells using a large scale drug repurposing collectionDOI 10.6019/CHEMBL4495564Identification of inhibitors of SARS-Cov2 M-Pro enzymatic activity using a small molecule repurposing screenDOI 10.6019/CHEMBL4495565Cytopathic SARS-Cov2 screening on VERO-E6 cells in a large repurposing effortDOI 10.1021/acs.jmedchem.5b01582A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis.PMID 26629594A Novel Potent Oral Series of VEGFR2 Inhibitors Abrogate Tumor Growth by Inhibiting Angiogenesis.DOI 10.1016/j.bmc.2013.10.009Synthesis and biological evaluation of substituted 1,2,3-benzotriazines and pyrido[3,2-d]-1,2,3-triazines as inhibitors of vascular endothelial growth factor receptor-2.PMID 24189187Synthesis and biological evaluation of substituted 1,2,3-benzotriazines and pyrido[3,2-d]-1,2,3-triazines as inhibitors of vascular endothelial growth factor receptor-2.DOI 10.1021/np800816nIngol and ingenol diterpenes from the aerial parts of Euphorbia royleana and their antiangiogenic activities.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

4-(4-Pyridylmethyl)-1(2H)-phtalazinoneCAS 107558-48-5
4-(4-chlorobenzyl)phthalazin-1(2H)-oneCAS 53242-88-9
MY 5445CAS 78351-75-4
(4-Benzyl-1-oxophthalazin-2(1H)-yl)acetic acidCAS 114897-85-7
4-Benzyl-1(2H)-phthalazinoneCAS 32003-14-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 120685-11-2MidostaurinCAS 146535-11-76,7-Dimethoxy-3-phenylquinoxalineCAS 189232-42-6BohemineCAS 443913-73-3VandetanibCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 212142-18-2

What are the key identifiers for Vatalanib Succinate (CAS 212142-18-2)?

Vatalanib Succinate is identified by CAS 212142-18-2, with molecular formula C24H21ClN4O4, molecular weight 464.9, InChIKey LLDWLPRYLVPDTG-UHFFFAOYSA-N.

Does CAS 212142-18-2 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Vascular endothelial growth factor receptor 2, Vascular endothelial growth factor receptor 3, Vascular endothelial growth factor receptor 1, Platelet-derived growth factor receptor beta, Mast/stem cell growth factor receptor Kit. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 212142-18-2?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Vatalanib Succinate?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 212142-18-2 available for quotation?

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