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Home/Compounds/CAS 21392-57-4
Formula C17H14O4MW 282.29Research-use catalog entryCOA/SDS by request

5,7-Dimethoxyflavone

CAS Number: 21392-57-4

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Available Options

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1 mg
Purity
98%
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100 mg
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Package
100 mg
Purity
98%
Price
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Availability
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Delivery
Shipping review required

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Loading RDKit molecule structure...
InChIKey: JRFZSUMZAUHNSL-UHFFFAOYSA-NC17H14O4 | MW 282.29

Chemical Absolute Identifiers

CAS Number

21392-57-4

PubChem CID

88881

Molecular Formula

C17H14O4

Molecular Weight

282.29 g/mol

Exact Mass

282.089209

InChIKey

JRFZSUMZAUHNSL-UHFFFAOYSA-N

IUPAC Name

5,7-dimethoxy-2-phenylchromen-4-one

SMILES String

COC1=CC2=C(C(=C1)OC)C(=O)C=C(O2)C3=CC=CC=C3

Physical Properties

Melting Point

154.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

5,7-Dimethoxyflavone (CAS 21392-57-4) is listed in the Life Science portfolio, with molecular formula C17H14O4 and molecular weight 282. 29 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Analytical ScienceLife Science ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Broad substrate specificity ATP-binding cassette transporter ABCG2 (Homo sapiens) — 2 assays; ATPase family AAA domain-containing protein 5 (Homo sapiens) — 2 assays; Tyrosyl-DNA phosphodiesterase 1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Broad substrate specificity ATP-binding cassette transporter ABCG2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.04

Experimental evidence source: ChEMBL

ATPase family AAA domain-containing protein 5

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Tyrosyl-DNA phosphodiesterase 1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

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  • Use personal protective equipment and emergency procedures.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

5,7-Dimethoxyflavone

Names & Synonyms

Chrysin dimethyl etherChrysin 5,7-dimethyl ether5,7-dimethoxy-2-phenyl-4H-1-benzopyran-4-one4H-1-Benzopyran-4-one, 5,7-dimethoxy-2-phenyl-Chrysin dimethylether
Show all synonyms
Dimethylchrysin5,7-Dimethoxy-2-phenyl-chromen-4-oneChrysin DME5,7-Dimethoxy FlavoneChrysindimethyletherChrysin-Dimethylether5,7 dimethoxyflavoneSpectrum_0003645,7-Dimethoxy-FlavoneSpecPlus_000913Chrysin - dimethyl etherDimethoxyflavone, 5,7-Spectrum2_001359Spectrum3_001034
External Identifiers
EC NUMBER: 979-686-7DSSTOX SUBSTANCE ID: DTXSID50175656CHEMBL ID: CHEMBL275391CHEBI ID: CHEBI:3684UNII: J8HQQ4R4F2HMDB ID: HMDB0036620KEGG ID: C10029METABOLOMICS WORKBENCH ID: 23273WIKIDATA ID: Q27106162
Experimental Spectrum References
13C NMR SpectraATR-IR Spectra — Forensic Spectral ResearchRaman Spectra — Forensic Spectral Research
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c03124Discovery of the 2,3-Dihydrobenzopyrane-4-one as a Potent FTO Inhibitor against Obesity-Related Metabolic Diseases.PMID 40152179Discovery of the 2,3-Dihydrobenzopyrane-4-one as a Potent FTO Inhibitor against Obesity-Related Metabolic Diseases.DOI 10.6019/CHEMBL4651402Screening of ~5500 FDA-approved drugs and clinical candidates for anti-SARS-CoV-2 activityDOI 10.1016/j.bmcl.2020.127606Effect of methoxyflavones contained in Kaempferia parviflora on CRE-mediated transcription in PC12D cells.PMID 33038547Effect of methoxyflavones contained in Kaempferia parviflora on CRE-mediated transcription in PC12D cells.DOI 10.1016/j.bmcl.2016.12.051Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.DOI 10.1016/j.bmcl.2017.03.057Identification and structure activity relationship of novel flavone derivatives that inhibit the production of nitric oxide and PGE2 in LPS-induced RAW 264.7 cells.PMID 28049590Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Sodium 9,10-dimethoxyanthracene-2-sulphonateCAS 67580-39-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 21392-57-4

What are the key identifiers for 5,7-Dimethoxyflavone (CAS 21392-57-4)?

5,7-Dimethoxyflavone is identified by CAS 21392-57-4, with molecular formula C17H14O4, molecular weight 282.29, InChIKey JRFZSUMZAUHNSL-UHFFFAOYSA-N.

Does CAS 21392-57-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Broad substrate specificity ATP-binding cassette transporter ABCG2, ATPase family AAA domain-containing protein 5, Tyrosyl-DNA phosphodiesterase 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 21392-57-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 5,7-Dimethoxyflavone?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 21392-57-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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