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Home/Compounds/CAS 217082-58-1
Formula C69H111N23O16SMW 1550.8Research-use catalog entryCOA/SDS by request

Apelin-13

CAS Number: 217082-58-1

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Loading RDKit molecule structure...
InChIKey: XXCCRHIAIBQDPX-PEWBXTNBSA-NC69H111N23O16S | MW 1550.8

Chemical Absolute Identifiers

CAS Number

217082-58-1

PubChem CID

25078060

Molecular Formula

C69H111N23O16S

Molecular Weight

1550.8 g/mol

Exact Mass

1549.829986

InChIKey

XXCCRHIAIBQDPX-PEWBXTNBSA-N

IUPAC Name

(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid

SMILES String

CC(C)C[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N2CCC[C@H]2C(=O)N[C@@H](CCSC)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H]5CCCN5C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCC(=O)N)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Apelin-13 (CAS 217082-58-1) is listed in the Life Science portfolio, with molecular formula C69H111N23O16S and molecular weight 1550. 80 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for life-science research and analytical workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Life Science ResearchPeptide ResearchResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Apelin receptor (Homo sapiens) — 11 assays; Adhesion G-protein coupled receptor F1 (Homo sapiens) — 3 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 3 assays; Beta-2 adrenergic receptor (Homo sapiens) — 3 assays; C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Apelin receptor

Homo sapiens · SINGLE PROTEIN · 11 qualifying assays · 5 documents · best pChEMBL 10.3

Experimental evidence source: ChEMBL

Adhesion G-protein coupled receptor F1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Beta-2 adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

C5a anaphylatoxin chemotactic receptor 1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Apelin-13

Names & Synonyms

apelin-13 peptideL-Phenylalanine, L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-(Pyr1)-Apelin-13Apelin 13Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe
Show all synonyms
Apelin-13 (human, bovine, mouse, rat)QRPRLSHKGPMPF[125I]apelin-13L-glutaminyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-seryl-L-histidyl-L-lysylglycyl-L-prolyl-L-methionyl-L-prolyl-L-phenylalanineQ-R-P-R-L-S-H-K-G-P-M-P-FL-Gln-L-Arg-L-Pro-L-Arg-L-Leu-L-Ser-L-His-L-Lys-L-Gly-L-Pro-L-Met-L-Pro-L-PheApelin-13 (human, bovine, mouse, rat) (H-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH)
External Identifiers
CHEMBL ID: CHEMBL414173CHEBI ID: CHEBI:80131METABOLOMICS WORKBENCH ID: 42127WIKIDATA ID: Q27074480
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c00110Unnatural Amino Acids: Strategies, Designs, and Applications in Medicinal Chemistry and Drug Discovery.DOI 10.6019/CHEMBL5442687EUbOPEN Chemogenomics Library - GPCR Dose-ResposePMID 39527066Unnatural Amino Acids: Strategies, Designs, and Applications in Medicinal Chemistry and Drug Discovery.DOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3DOI 10.6019/CHEMBL5058564Tm Shift (DSF) assay results for EUbOPEN Chemogenomis Library 2 (Incucyte)DOI 10.1021/acs.jmedchem.0c01941Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.DOI 10.1021/acs.jmedchem.1c01504Identification of a Hydroxypyrimidinone Compound (<b>21</b>) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure.PMID 33524256Constraining the Side Chain of C-Terminal Amino Acids in Apelin-13 Greatly Increases Affinity, Modulates Signaling, and Improves the Pharmacokinetic Profile.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

H-Met-glu-val-gly-trp-tyr-arg-ser-pro-phe-ser-arg-val-val-his-leu-tyr-arg-asn-gly-lys-OHCAS 149635-73-4
N-Formylmethionyl-leucyl-phenylalanyl-lysineCAS 67247-11-4
Bradykinin (1-5)CAS 23815-89-6
H-Met-arg-phe-ala-OHCAS 67368-29-0
H-Leu-his-OHCAS 38062-72-5

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 149635-73-4H-Met-glu-val-gly-trp-tyr-arg-ser-pro-phe-ser-arg-val-val-his-leu-tyr-arg-asn-gly-lys-OHCAS 67247-11-4N-Formylmethionyl-leucyl-phenylalanyl-lysineCAS 102146-07-6DpcpxCAS 138402-11-6IrbesartanCAS 139481-59-7CandesartanCAS 159182-43-14-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]phenyl]-benzenesulfonamideCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 217082-58-1

What are the key identifiers for Apelin-13 (CAS 217082-58-1)?

Apelin-13 is identified by CAS 217082-58-1, with molecular formula C69H111N23O16S, molecular weight 1550.8, InChIKey XXCCRHIAIBQDPX-PEWBXTNBSA-N.

Does CAS 217082-58-1 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Apelin receptor, Adhesion G-protein coupled receptor F1, Alpha-2A adrenergic receptor, Beta-2 adrenergic receptor, C5a anaphylatoxin chemotactic receptor 1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 217082-58-1?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Apelin-13?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 217082-58-1 available for quotation?

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