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Home/Compounds/CAS 217645-70-0
Formula C21H24ClFN4O3MW 434.9Research-use catalog entryCOA/SDS by request

BX-471 free base

CAS Number: 217645-70-0

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Loading RDKit molecule structure...
InChIKey: XQYASZNUFDVMFH-CQSZACIVSA-NC21H24ClFN4O3 | MW 434.9

Chemical Absolute Identifiers

CAS Number

217645-70-0

PubChem CID

512282

Molecular Formula

C21H24ClFN4O3

Molecular Weight

434.9 g/mol

Exact Mass

434.152097

InChIKey

XQYASZNUFDVMFH-CQSZACIVSA-N

IUPAC Name

[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]phenyl]urea

SMILES String

C[C@@H]1CN(Cc2ccc(F)cc2)CCN1C(=O)COc1ccc(Cl)cc1NC(N)=O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

BX-471 free base (CAS 217645-70-0) is listed in the Pharmaceutical Intermediates portfolio, with molecular formula C21H24ClFN4O3 and molecular weight 434. 90 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research-stage medicinal chemistry and intermediate synthesis workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Pharmaceutical Intermediate ResearchResearch intermediateCustom synthesis building blockPharmaceutical intermediate researchResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: C-C chemokine receptor type 1 (Homo sapiens) — 12 assays; C-C chemokine receptor type 1 (Mus musculus) — 2 assays; G-protein coupled receptor 35 (Homo sapiens) — 2 assays; Adhesion G-protein coupled receptor F1 (Homo sapiens) — 3 assays; Alpha-2A adrenergic receptor (Homo sapiens) — 3 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

C-C chemokine receptor type 1

Homo sapiens · SINGLE PROTEIN · 12 qualifying assays · 7 documents · best pChEMBL 9

Experimental evidence source: ChEMBL

C-C chemokine receptor type 1

Mus musculus · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 6.7

Experimental evidence source: ChEMBL

G-protein coupled receptor 35

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 2 documents · best pChEMBL 5.97

Experimental evidence source: ChEMBL

Adhesion G-protein coupled receptor F1

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Alpha-2A adrenergic receptor

Homo sapiens · SINGLE PROTEIN · 3 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

BX-471 free base

Names & Synonyms

(2R)-1-[[[4-Chloro-2-(ureido)phenoxy]methyl]carbonyl]-2-methyl-4-(4-fluorobenzyl)piperazine(2R)-1-(((4-Chloro-2-(ureido)phenoxy)methyl)carbonyl)-2-methyl-4-(4-fluorobenzyl)piperazineUrea, N-(5-chloro-2-(2-((2R)-4-((4-fluorophenyl)methyl)-2-methyl-1-piperazinyl)-2-oxoethoxy)phenyl)-Urea, N-[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]-(R)-1-(5-chloro-2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)phenyl)urea
Show all synonyms
C21H24ClFN4O3[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-piperazin-1-yl]-2-oxo-ethoxy]phenyl]ureaBX-471free baseZk-811752(bx-471)1-(2-(2-((R)-4-(4-Fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)-5-chlorophenyl)ureaBX-471ZK 811752?B6060(R)-1-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)-5-chlorophenyl)urea(R)-1-[5-Chloro-2-[2-[4-(4-fluorobenzyl)-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]urea(R)-1-(2-(2-(4-(4-fluorobenzyl)-2-methylpiperazin-1-yl)-2-oxoethoxy)-5-chlorophenyl)urea hydrochlorideN-[5-Chloro-2-(2-{(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl}-2-oxoethoxy)phenyl]urea
External Identifiers
EC NUMBER: 803-071-3DSSTOX SUBSTANCE ID: DTXSID10176164CHEMBL ID: CHEMBL232656UNII: 76K17ZG4ZNWIKIDATA ID: Q27075605
Literature & Patent References
DOI 10.6019/CHEMBL5442687EUbOPEN Chemogenomics Library - GPCR Dose-ResposeDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724562Toxicity screen in isolated B cell assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724581Toxicity screen in purified B cell assay results for EUbOPEN Chemogenomics LibraryDOI 10.6019/CHEMBL5724801EUbOPEN Chemogenomics Library - MultiplexDOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.6019/CHEMBL5058564Tm Shift (DSF) assay results for EUbOPEN Chemogenomis Library 2 (Incucyte)

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

Tak-220CAS 333994-00-6

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 170729-80-35-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-1,2-dihydro-1,2,4-triazol-3-oneCAS 102146-07-6DpcpxCAS 138402-11-6IrbesartanCAS 698394-73-9VercirnonCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 217645-70-0

What are the key identifiers for BX-471 free base (CAS 217645-70-0)?

BX-471 free base is identified by CAS 217645-70-0, with molecular formula C21H24ClFN4O3, molecular weight 434.9, InChIKey XQYASZNUFDVMFH-CQSZACIVSA-N.

Does CAS 217645-70-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with C-C chemokine receptor type 1, C-C chemokine receptor type 1, G-protein coupled receptor 35, Adhesion G-protein coupled receptor F1, Alpha-2A adrenergic receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 217645-70-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for BX-471 free base?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 217645-70-0 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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