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Home/Compounds/CAS 21829-25-4
Formula C17H18N2O6MW 346.3Research-use catalog entryCOA/SDS by request

Nifedipine

CAS Number: 21829-25-4

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Loading RDKit molecule structure...
InChIKey: HYIMSNHJOBLJNT-UHFFFAOYSA-NC17H18N2O6 | MW 346.3

Chemical Absolute Identifiers

CAS Number

21829-25-4

PubChem CID

4485

Molecular Formula

C17H18N2O6

Molecular Weight

346.3 g/mol

Exact Mass

346.116486

InChIKey

HYIMSNHJOBLJNT-UHFFFAOYSA-N

IUPAC Name

dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

SMILES String

CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC=CC=C2[N+](=O)[O-])C(=O)OC

Physical Properties

Appearance

Nifedipine appears as odorless yellow crystals or powder. Tasteless. (NTP, 1992)

Melting Point

172–174 °C

Show more physical data

Vapor Pressure

Estimated value, unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Nifedipine (CAS 21829-25-4) is listed in the Materials Science portfolio, with molecular formula C17H18N2O6 and molecular weight 346. 30 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for materials chemistry research and formulation screening workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Materials SciencePolymer ScienceResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens) — 10 assays; Voltage-dependent L-type calcium channel subunit alpha-1C (Oryctolagus cuniculus) — 4 assays; Voltage-dependent L-type calcium channel subunit alpha-1D (Rattus norvegicus) — 3 assays; Voltage-dependent L-type calcium channel subunit alpha-1C (Rattus norvegicus) — 3 assays; Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus) — 6 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Voltage-dependent L-type calcium channel subunit alpha-1C

Homo sapiens · SINGLE PROTEIN · 10 qualifying assays · 6 documents · best pChEMBL 9.4

Experimental evidence source: ChEMBL

Voltage-dependent L-type calcium channel subunit alpha-1C

Oryctolagus cuniculus · SINGLE PROTEIN · 4 qualifying assays · 3 documents · best pChEMBL 9

Experimental evidence source: ChEMBL

Voltage-dependent L-type calcium channel subunit alpha-1D

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8.92

Experimental evidence source: ChEMBL

Voltage-dependent L-type calcium channel subunit alpha-1C

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 3 documents · best pChEMBL 8.85

Experimental evidence source: ChEMBL

Voltage-dependent L-type calcium channel subunit alpha-1C

Cavia porcellus · SINGLE PROTEIN · 6 qualifying assays · 4 documents · best pChEMBL 8.59

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

  • Keep container tightly closed and dry.
  • Store in a well-ventilated place.

PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste product.
  • Dispose of remaining and non-recyclable solutions to a licensed company.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Nifedipine

Names & Synonyms

ProcardiaAdalatProcardia XLCitilatOxcord
Show all synonyms
Adalat CCFenihidineBay-a-1040CoractenAfeditab CRNifedipinoNifedipinumNifedicalAfeditabCalcilatBAY A 10401,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl esterNifensar XLAdipine XL
External Identifiers
EC NUMBER: 244-598-3DSSTOX SUBSTANCE ID: DTXSID2025715CHEMBL ID: CHEMBL193CHEBI ID: CHEBI:7565UNII: I9ZF7L6G2LDRUGBANK ID: DB01115HMDB ID: HMDB0015247KEGG ID: C07266KEGG ID: D00437METABOLOMICS WORKBENCH ID: 43341NCI THESAURUS CODE: C29290PHARMGKB ID: PA450631RXCUI: 7417WIKIDATA ID: Q39111
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Forensic Spectral ResearchFTIR SpectraRaman Spectra — Forensic Spectral ResearchUV Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c03146Discovery of Isobenzofuran-1(3<i>H</i>)-one Derivatives as Selective TREK-1 Inhibitors with In Vitro and In Vivo Neuroprotective Effects.DOI 10.1021/acs.jmedchem.5c00419Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.DOI 10.1021/acs.jmedchem.5c00597Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites.PMID 40040241Discovery of Isobenzofuran-1(3<i>H</i>)-one Derivatives as Selective TREK-1 Inhibitors with In Vitro and In Vivo Neuroprotective Effects.PMID 40179277Development of Next-Generation Antimalarial Acridones with Radical Cure Potential.PMID 40450579Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites.DOI 10.1016/j.ejmech.2023.116117Targeting autophagy drug discovery: Targets, indications and development trends.DOI 10.1016/j.isci.2024.108907Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Methyl o-benzoylbenzoateCAS 606-28-0
4-hydroxy-TEMPO benzoateCAS 3225-26-1
2,2-Dimethoxy-2-phenylacetophenoneCAS 24650-42-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 23593-75-1ClotrimazoleCAS 22916-47-8MiconazoleCAS 114-07-8ErythromycinCAS 552-89-62-NitrobenzaldehydeCAS 79794-75-5LoratadineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

RFQ questions for CAS 21829-25-4

What are the key identifiers for Nifedipine (CAS 21829-25-4)?

Nifedipine is identified by CAS 21829-25-4, with molecular formula C17H18N2O6, molecular weight 346.3, InChIKey HYIMSNHJOBLJNT-UHFFFAOYSA-N.

Does CAS 21829-25-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1D, Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-dependent L-type calcium channel subunit alpha-1C. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 21829-25-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Nifedipine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 21829-25-4 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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