MolGraphChemical Intelligence
Active Chemical RecordCatalog PreviewCatalog ready

3,3,3-Trifluoro-2-(7-methyl-1H-indol-3-yl)propanoic acid

CAS 2197062-23-8Formula C12H10F3NO2MW 257.21PubChem 131637696

A trifluorinated indole derivative, 3,3,3-Trifluoro-2-(7-methyl-1H-indol-3-yl)propanoic acid is a research chemical with a molecular formula C12H10F3NO2. It features a 7-methyl-1H-indole core linked to a trifluoropropanoic acid moiety, making it of interest in medicinal chemistry and drug discovery research.

Loading RDKit molecule structure...
InChIKey: ZJCXVAQFBOIWEI-UHFFFAOYSA-NC12H10F3NO2 | MW 257.21

Chemical Identity

Molecular Formula

C12H10F3NO2

Molecular Weight

257.21 g/mol

Exact Mass

257.066363

PubChem CID

131637696

SMILES String

Cc1cccc2c(C(C(=O)O)C(F)(F)F)c[nH]c12

Names & Synonyms

F476294
External Identifiers
MFCD29038569CHEMBL4870872AKOS037654236KS-9276

Catalog Overview

3,3,3-Trifluoro-2-(7-methyl-1H-indol-3-yl)propanoic acid is an organic compound characterized by an indole heterocyclic ring system substituted with a methyl group at the 7-position and a 3,3,3-trifluoro-2-propanoic acid chain at the 3-position. With a molecular weight of 257.21 g/mol and the chemical formula C12H10F3NO2, this compound presents a unique structural motif combining a biologically relevant indole scaffold with a trifluoromethyl group, which is often incorporated into drug candidates to modulate physicochemical properties and metabolic stability. It is primarily intended for research and development applications.

Use Context

  • Research chemical sourcing
  • Custom synthesis and catalog availability review
  • COA, SDS, pricing, and fulfillment workflow

Physical Data

Estimated

Estimated / predicted physical property values for catalog reference.

Appearance

White crystalline powder

Physical State

Solid

Melting Point

165.0 °C

Boiling Point

400.0 °C

Density

1.4 g/cm³

Water Solubility

Slightly soluble

Flash Point

250.0 °C

Applications / Classifications

Research intermediateCustom synthesis building block

Biological Target Reference

No verified biological target assignment. This compound is listed primarily as a research or synthetic intermediate.

Preliminary Safety-Style Reference

Preliminary

Preliminary safety-style information for reference only. Not a supplier SDS.

Handling and Storage
  • Handle 3,3,3-Trifluoro-2-(7-methyl-1H-indol-3-yl)propanoic acid with appropriate personal protective equipment, including gloves, eye protection, and a lab coat. Use in a well-ventilated area or fume hood to avoid inhalation. Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water. Consult the Safety Data Sheet (SDS) for detailed hazard information and safe handling procedures. Store in a cool, dry place, tightly sealed. This product is for research use only and not for human or animal therapeutic or diagnostic use.

Related Products / Graph Discovery

Related products, derivatives, keywords, and application cues for catalog discovery.

Related products and analog discovery will be available as catalog graph data is expanded.