MolGraph
CompoundsDocumentationComplianceAbout
MolGraph

Research chemical sourcing and molecular building block RFQ workflows.

MolGraph is operated by Tessorix Inc.

support@molgraph.com

Products are intended for laboratory research use only and are not for human or veterinary use.

Compounds

  • Compound catalog
  • CAS Search

Company

  • About
  • Contact

Documentation

  • Quality Documentation
  • SDS Disclaimer

Compliance

  • Compliance

Legal

  • Terms
  • Privacy

Copyright © 2026 MolGraph. All Rights Reserved.

Home/Compounds/CAS 223387-75-5
Formula C12H9ClN2O4MW 280.66Research-use catalog entryCOA/SDS by request

FG-2216

CAS Number: 223387-75-5

Sourcing & RFQ

Submit an RFQ to review pricing, availability, lead time, pack size, purity, COA, and supplier SDS for this catalog entry.

Available options

Available Options

Package
1 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
10 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
100 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
2 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
25 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
250 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
5 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required
Package
50 mg
Purity
99%
Price
Request review
Availability
Shipping review required
Delivery
Shipping review required

Shipping review is required before pricing or stock can be confirmed publicly. Shipping, duties, and documentation fees are confirmed before order acceptance.

Loading RDKit molecule structure...
InChIKey: OUQVKRKGTAUJQA-UHFFFAOYSA-NC12H9ClN2O4 | MW 280.66

Chemical Absolute Identifiers

CAS Number

223387-75-5

PubChem CID

6914666

Molecular Formula

C12H9ClN2O4

Molecular Weight

280.66 g/mol

Exact Mass

280.025085

InChIKey

OUQVKRKGTAUJQA-UHFFFAOYSA-N

IUPAC Name

2-[(1-chloro-4-hydroxyisoquinoline-3-carbonyl)amino]acetic acid

SMILES String

O=C(O)CNC(=O)c1nc(Cl)c2ccccc2c1O

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

FG-2216 (CAS 223387-75-5) is listed in the Advanced Chemicals portfolio, with molecular formula C12H9ClN2O4 and molecular weight 280. 66 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Egl nine homolog 1 (Homo sapiens) — 15 assays; Gamma-butyrobetaine dioxygenase (Pseudomonas sp. (strain AK-1)) — 3 assays; Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens) — 5 assays; Gamma-butyrobetaine dioxygenase (Homo sapiens) — 4 assays; Methylcytosine dioxygenase TET1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Egl nine homolog 1

Homo sapiens · SINGLE PROTEIN · 15 qualifying assays · 10 documents · best pChEMBL 7.16

Experimental evidence source: ChEMBL

Gamma-butyrobetaine dioxygenase

Pseudomonas sp. (strain AK-1) · SINGLE PROTEIN · 3 qualifying assays · 1 documents · best pChEMBL 6.68

Experimental evidence source: ChEMBL

Alpha-ketoglutarate-dependent dioxygenase FTO

Homo sapiens · SINGLE PROTEIN · 5 qualifying assays · 4 documents · best pChEMBL 5.55

Experimental evidence source: ChEMBL

Gamma-butyrobetaine dioxygenase

Homo sapiens · SINGLE PROTEIN · 4 qualifying assays · 1 documents · best pChEMBL 4.89

Experimental evidence source: ChEMBL

Methylcytosine dioxygenase TET1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

For supplier-issued SDS or COA, submit a documentation request.

Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

FG-2216

Names & Synonyms

FG 2216(((1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl)amino)acetic acid1-Chloro-N-(hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamide2-[(1-chloro-4-hydroxyisoquinolin-3-yl)formamido]acetic acid2-((1-chloro-4-hydroxyisoquinolin-3-yl)formamido)acetic acid
Show all synonyms
FG 2216 (erythropoietic agent)(1-chloro-4-hydroxyisoquinoline-3-carbonyl)glycineN-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycineN-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE2-(1-chloro-4-hydroxyisoquinoline-3-carboxamido)acetic acidGlycine, N-[(1-chloro-4-hydroxy-3-isoquinolinyl)carbonyl]-1-Chloro-N- (hydroxyformylmethyl-4-hydroxyisoquinoline-3-carboxamideYM 311UN9Isoquinoline 34bqx4ie6IOX32y34
External Identifiers
EC NUMBER: 803-250-6CHEMBL ID: CHEMBL426560UNII: RU921DS4Z5DRUGBANK ID: DB08687HMDB ID: HMDB0252244METABOLOMICS WORKBENCH ID: 151807WIKIDATA ID: Q27097876
Literature & Patent References
DOI 10.1016/j.bmcl.2024.129799Discovery of DS44470011: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia.DOI 10.1016/j.ejmech.2024.116526Small molecules that regulate the N<sup>6</sup>-methyladenosine RNA modification as potential anti-cancer agents.DOI 10.1021/acs.jmedchem.3c01820Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.PMID 38294854Focused Screening Identifies Different Sensitivities of Human TET Oxygenases to the Oncometabolite 2-Hydroxyglutarate.PMID 38754564Discovery of DS44470011: An oral hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of renal anemia.PMID 38805939Small molecules that regulate the N<sup>6</sup>-methyladenosine RNA modification as potential anti-cancer agents.DOI 10.1021/acs.jmedchem.1c01204Structure-Based Design of Selective Fat Mass and Obesity Associated Protein (FTO) Inhibitors.DOI 10.1021/acs.jmedchem.1c01694Inhibition of AlkB Nucleic Acid Demethylases: Promising New Epigenetic Targets.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Show non-linked catalog cues

Non-public related references

Methyl 1-chloroisoquinoline-3-carboxylateCAS 349552-70-1
3-Chloroisoquinolin-4-olCAS 101774-33-8
Isoquinoline-4-carboxylic acidCAS 7159-36-6
(1-Chloroisoquinolin-4-yl)boronic acidCAS 848841-48-5
1-Chloroisoquinoline-4-carbonitrileCAS 53491-80-8

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 110-15-6Succinic AcidCAS 520-36-5ApigeninCAS 528-48-3FisetinCAS 60940-34-3EbselenCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 223387-75-5

What are the key identifiers for FG-2216 (CAS 223387-75-5)?

FG-2216 is identified by CAS 223387-75-5, with molecular formula C12H9ClN2O4, molecular weight 280.66, InChIKey OUQVKRKGTAUJQA-UHFFFAOYSA-N.

Does CAS 223387-75-5 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Egl nine homolog 1, Gamma-butyrobetaine dioxygenase, Alpha-ketoglutarate-dependent dioxygenase FTO, Gamma-butyrobetaine dioxygenase, Methylcytosine dioxygenase TET1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 223387-75-5?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for FG-2216?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 223387-75-5 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

Can MolGraph support bulk sourcing or custom synthesis review?

Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.