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Home/Compounds/CAS 22608-11-3
Formula C20H18O5MW 338.4Research-use catalog entryCOA/SDS by request

Demethoxycurcumin

CAS Number: 22608-11-3

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Loading RDKit molecule structure...
InChIKey: HJTVQHVGMGKONQ-LUZURFALSA-NC20H18O5 | MW 338.4

Chemical Absolute Identifiers

CAS Number

22608-11-3

PubChem CID

5469424

Molecular Formula

C20H18O5

Molecular Weight

338.4 g/mol

Exact Mass

338.115424

InChIKey

HJTVQHVGMGKONQ-LUZURFALSA-N

IUPAC Name

(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dione

SMILES String

COc1cc(/C=C/C(=O)CC(=O)/C=C/c2ccc(O)cc2)ccc1O

Physical Properties

Melting Point

168.0 °C

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Demethoxycurcumin (CAS 22608-11-3) is listed in the Advanced Chemicals portfolio, with molecular formula C20H18O5 and molecular weight 338. 40 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: ATP-dependent translocase ABCB1 (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

ATP-dependent translocase ABCB1

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 5.81

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

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Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

Demethoxycurcumin

Names & Synonyms

curcumin IIdesmethoxycurcuminDemethoxy CurcuminBHCFM4-Hydroxycinnamoyl(feroyl)methane
Show all synonyms
Feruloyl-P-hydroxycinnnamoylmethanedemethoxy-curcumin(1E,4Z,6E)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-onemonodemethoxycurcumin(E/Z)-Demethoxycurcumin1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)hepta-1,6-diene-3,5-dionecurcuminII(2E)-Demethoxy Curcumin1,6-Heptadiene-3,5-dione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-p-Hydroxycinnamoyl-feruloylmethane(1E,6E)-1-(4-HYDROXY-3-METHOXY-PHENYL)-7-(4-HYDROXYPHENYL)HEPTA-1,6-DI ENE-3,5-DIONE(1E,6E)-1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione4-hydroxycinnamoyl(feruloyl)methane1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
External Identifiers
EC NUMBER: 607-465-4EC NUMBER: 663-429-8DSSTOX SUBSTANCE ID: DTXSID00873751CHEMBL ID: CHEMBL105360CHEMBL ID: CHEMBL179512CHEBI ID: CHEBI:65737UNII: W2F8059T80HMDB ID: HMDB0033801METABOLOMICS WORKBENCH ID: 64104WIKIDATA ID: Q5264607
Experimental Spectrum References
13C NMR SpectraVapor Phase IR Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.4c01116In Search for Inhibitors of Human Aldo-Keto Reductase 1B10 (AKR1B10) as Novel Agents to Fight Cancer and Chemoresistance: Current State-of-the-Art and Prospects.PMID 39757466In Search for Inhibitors of Human Aldo-Keto Reductase 1B10 (AKR1B10) as Novel Agents to Fight Cancer and Chemoresistance: Current State-of-the-Art and Prospects.DOI 10.6019/EOS300108ECBD screening data for assay EOS300108DOI 10.1016/j.ejmech.2022.114542Cancer multidrug-resistance reversal by ABCB1 inhibition: A recent update.PMID 35751979Cancer multidrug-resistance reversal by ABCB1 inhibition: A recent update.DOI 10.1021/acs.jmedchem.1c00386Chemical Biology of Sortase A Inhibition: A Gateway to Anti-infective Therapeutic Agents.PMID 34516107Chemical Biology of Sortase A Inhibition: A Gateway to Anti-infective Therapeutic Agents.DOI 10.1016/j.ejmech.2020.112787A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(10)-GingerolCAS 23513-15-7
2-Hydroxy-4-MethoxybenzaldehydeCAS 673-22-3
2,5-DihydroxybenzaldehydeCAS 1194-98-5
2,6-Dimethoxybenzoic AcidCAS 1466-76-8
DaphnoretinCAS 2034-69-7

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 110703-94-1ZopolrestatCAS 120685-11-2MidostaurinCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 22608-11-3

What are the key identifiers for Demethoxycurcumin (CAS 22608-11-3)?

Demethoxycurcumin is identified by CAS 22608-11-3, with molecular formula C20H18O5, molecular weight 338.4, InChIKey HJTVQHVGMGKONQ-LUZURFALSA-N.

Does CAS 22608-11-3 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with ATP-dependent translocase ABCB1. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 22608-11-3?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Demethoxycurcumin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 22608-11-3 available for quotation?

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