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Home/Compounds/CAS 2373-80-0
Formula C10H8O4MW 192.17Research-use catalog entryCOA/SDS by request

3,4-Methylenedioxycinnamic acid

CAS Number: 2373-80-0

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Loading RDKit molecule structure...
InChIKey: QFQYZMGOKIROEC-DUXPYHPUSA-NC10H8O4 | MW 192.17

Chemical Absolute Identifiers

CAS Number

2373-80-0

PubChem CID

643181

Molecular Formula

C10H8O4

Molecular Weight

192.17 g/mol

Exact Mass

192.042259

InChIKey

QFQYZMGOKIROEC-DUXPYHPUSA-N

IUPAC Name

(E)-3-(1,3-benzodioxol-5-yl)prop-2-enoic acid

SMILES String

C1OC2=C(O1)C=C(C=C2)/C=C/C(=O)O

Physical Properties

No physical property values available.

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Vapor Pressure

Estimated very low; unit not specified

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

3,4-Methylenedioxycinnamic acid (CAS 2373-80-0) is listed in the Advanced Chemicals portfolio, with molecular formula C10H8O4 and molecular weight 192. 17 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Transitional endoplasmic reticulum ATPase (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Transitional endoplasmic reticulum ATPase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Names & Synonyms / External Identifiers

Chemical Name

3,4-Methylenedioxycinnamic acid

Names & Synonyms

3,4-(METHYLENEDIOXY)CINNAMIC ACID2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-, (E)-3,4-METHYLENEDIOXYCINNAMIC ACID, (E)-3,4-METHYLENEDIOXYCINNAMIC ACID [WHO-DD](2E)-3-(1,3-dioxaindan-5-yl)prop-2-enoic acid
Show all synonyms
2Propenoic acid, 3(1,3benzodioxol5yl)3,4(Methylenedioxy)cinnamic acid, predominantly trans3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid(E)-3,4-(Methylenedioxy)cinnamic acid(2e)-3-(1,3-benzodioxol-5-yl)acrylic acid(2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enoic acid3-(1,3-benzodioxol-5-yl)acrylic acid(E)-3-(benzo[d][1,3]dioxol-5-yl)acrylic acid2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-piperonyl acrylic acidMethylenedioxycinnamic acid2-Propenoic acid, 3-(1,3-benzodioxol-5-yl)-, (2E)-3-(1,3-benzodioxol-5-yl)-2-propenoic acid
External Identifiers
EC NUMBER: 887-122-5DSSTOX SUBSTANCE ID: DTXSID80901400CHEMBL ID: CHEMBL1173153CHEBI ID: CHEBI:81482UNII: X8H0WPJ08YKEGG ID: C18077METABOLOMICS WORKBENCH ID: 122657WIKIDATA ID: Q27155410
Experimental Spectrum References
13C NMR Spectra1D NMR Spectra1H NMR Spectra — Sigma-Aldrich Co. LLC.ATR-IR SpectraFTIR Spectra — Sigma-Aldrich Co. LLC.Raman Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2020.113148A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells.PMID 33476933A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells.DOI 10.1021/acs.jmedchem.6b00461Incorporation of Privileged Structures into Bevirimat Can Improve Activity against Wild-Type and Bevirimat-Resistant HIV-1.PMID 27676157Incorporation of Privileged Structures into Bevirimat Can Improve Activity against Wild-Type and Bevirimat-Resistant HIV-1.DOI 10.1016/j.ejmech.2015.03.056Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents.PMID 25847765Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents.DOI 10.1039/C3MD00251A2-Hydroxy-substituted cinnamic acids and acetanilides are selective growth inhibitors of Mycobacterium tuberculosisDOI 10.1021/jm400374qIdentification of cinnamic acid derivatives as novel antagonists of the prokaryotic proton-gated ion channel GLIC.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

(2E)-3-(6-Bromo-1,3-benzodioxol-5-yl)-2-propenoic acidCAS 27452-00-2
1,3-Benzodioxole, 5-ethenyl-CAS 7315-32-4
1,3-Benzodioxole-5-carbonyl chlorideCAS 25054-53-9
5-Chloro-1,3-benzodioxoleCAS 7228-38-8
2H-1,3-Benzodioxol-5-amine--hydrogen chloride (1/1)CAS 2620-45-3

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 27452-00-2(2E)-3-(6-Bromo-1,3-benzodioxol-5-yl)-2-propenoic acidCAS 7315-32-41,3-Benzodioxole, 5-ethenyl-CAS 25054-53-91,3-Benzodioxole-5-carbonyl chlorideCAS 7228-38-85-Chloro-1,3-benzodioxoleCAS 139110-80-8ZanamivirCAS 19337-97-4trans-3-(3-Pyridyl)acrylic acidCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylate

RFQ questions for CAS 2373-80-0

What are the key identifiers for 3,4-Methylenedioxycinnamic acid (CAS 2373-80-0)?

3,4-Methylenedioxycinnamic acid is identified by CAS 2373-80-0, with molecular formula C10H8O4, molecular weight 192.17, InChIKey QFQYZMGOKIROEC-DUXPYHPUSA-N.

Does CAS 2373-80-0 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Transitional endoplasmic reticulum ATPase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 2373-80-0?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 3,4-Methylenedioxycinnamic acid?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 2373-80-0 available for quotation?

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