Research chemical
CAS Number: 2378257-72-6
Product details
For laboratory research and professional procurement workflows.
PubChem CID
162472193
Exact Mass
957.374051
InChIKey
KZQITCSEFGTWRQ-OWAVIYFHSA-N
IUPAC Name
5-[4-[[4-[(2R)-2-[6-chloro-8-fluoro-7-(3-hydroxynaphthalen-1-yl)-4-(4-prop-2-enoylpiperazin-1-yl)quinazolin-2-yl]oxypropyl]piperazin-1-yl]methyl]piperidin-1-yl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
SMILES String
C=CC(=O)N1CCN(c2nc(O[C@H](C)CN3CCN(CC4CCN(c5ccc6c(c5)C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)CC3)nc3c(F)c(-c4cc(O)cc5ccccc45)c(Cl)cc23)CC1
Catalog navigation
Linked by recorded structural or research relationships, not interchangeable products. Check the exact CAS, specification and availability on the linked product page.
PROTAC KRAS G12C degrader-2 is identified by CAS 2378257-72-6, with molecular formula C51H53ClFN9O7, molecular weight 958.5, InChIKey KZQITCSEFGTWRQ-OWAVIYFHSA-N.
Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.
Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.
Availability, pack size, lead time, and pricing are confirmed through RFQ.
Submit the CAS number, quantity, purity requirement, and destination country for sourcing review.
No physical property values available.
Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.
Heavy atom count
69
H-bond acceptors
16
H-bond donors
2
Rotatable bonds
11
Ring count
10
Aromatic rings
5
Topological polar surface area
172.06 Ų
Computed LogP
5.49
Fragment-like structure rule
No
Lead-like structure rule
No
Drug-like structure rule
No
Structure family
n heterocycle ligand
Precious metal motif
No
Transition metal motif
No
Phosphine ligand motif
No
N-heterocycle motif
Yes
Boronic acid motif
No
Computed structure descriptors generated from molecular structure. These are not experimental physical property values, supplier specifications, SDS data, or bioactivity claims.
Structural features
PROTAC KRAS G12C degrader-2 (CAS 2378257-72-6) is maintained as a commercial cas reference with formula C51H53ClFN9O7, molecular weight 958. 50 g/mol, PubChem CID 162472193.
Sourcing context
Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.
Research use context
Use this page for CAS identity lookup, internal catalog search, and commercial discovery workflows; structure-derived tags include nitrogen-containing heterocycle.
Documentation needs
Review supplier documentation before handling; for research use only.
Safety and handling reference content is available through documentation requests.
For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.