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Home/Compounds/CAS 2380-63-4
Formula C5H5N5MW 135.13Research-use catalog entryCOA/SDS by request

1H-Pyrazolo[3,4-d]pyrimidin-4-amine

CAS Number: 2380-63-4

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Loading RDKit molecule structure...
InChIKey: LHCPRYRLDOSKHK-UHFFFAOYSA-NC5H5N5 | MW 135.13

Chemical Absolute Identifiers

CAS Number

2380-63-4

PubChem CID

75420

Molecular Formula

C5H5N5

Molecular Weight

135.13 g/mol

Exact Mass

135.054495

InChIKey

LHCPRYRLDOSKHK-UHFFFAOYSA-N

SMILES String

C1=NNC2=NC=NC(=C21)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

1H-Pyrazolo[3,4-d]pyrimidin-4-amine (CAS 2380-63-4) is listed in the Advanced Chemicals portfolio, with molecular formula C5H5N5 and molecular weight 135. 13 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Heterocyclic Building BlocksSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens) — 2 assays; Xanthine dehydrogenase/oxidase (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Leucine-rich repeat serine/threonine-protein kinase 2

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.95

Experimental evidence source: ChEMBL

Xanthine dehydrogenase/oxidase

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 4.52

Experimental evidence source: ChEMBL

Safety & Handling

Handling & Storage

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PPE

Respiratory protection if needed

First Aid

  • Do not give anything to an unconscious person.
  • Rinse mouth with water.

Stability / Reactivity

  • Stability and reactivity.
  • Carbon monoxide, carbon dioxide, nitrogen oxides.

Disposal

  • Waste The remaining and non-recyclable solutions should be handed over to a licensed company for disposal.
  • Contact a professional organization with a waste disposal license to handle this substance.
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Fire Fighting

  • If necessary, wear a self-contained breathing apparatus for firefighting.

Accidental Release

  • Do not generate dust when collecting and disposing.
  • Sweep and shovel up.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

1H-Pyrazolo[3,4-d]pyrimidin-4-amine

Names & Synonyms

4-Aminopyrazolo[3,4-d]pyrimidinePyrazoloadenine4-Amino-1H-pyrazolo[3,4-D]pyrimidine4-Aminopyrazolopyrimidine2H-Pyrazolo[3,4-d]pyrimidin-4-amine
Show all synonyms
1H-Pyrazolo[3,4-d]pyrimidin-4-ylamine4-Aminopyrazolo(3,4-d)pyrimidine4 APP8-Aza-7-deazaadenine4-Aminopyrazole(3,4-d)pyrimidine1H-Pyrazolo(3,4-d)pyrimidin-4-amine1H-Pyrazolo(3,4-d)pyrimidine, 4-amino-1H-Pyrazolo[3,4-d]pyrimidine, 4-amino-4-aminopyrazolo-(3,4-d)pyrimidine4-amino-pyrazolo(3,4-D)pyrimidine4-Aminopyrazole[3,4-d]pyrimidine4-Amino-pyrazolo[3,4-d]pyrimidinepyrazolo[5,4-d]pyrimidine-4-ylamine4-amino-1h-pyrazolo(3,4-d)pyrimidine1H-PYRAZOLO(3,4-D)PYRIMIDIN-4-YLAMINE
External Identifiers
EC NUMBER: 219-174-6DSSTOX SUBSTANCE ID: DTXSID3062362CHEMBL ID: CHEMBL388593UNII: 0356MAT9LXHMDB ID: HMDB0244899WIKIDATA ID: Q27247530
Experimental Spectrum References
13C NMR Spectra1H NMR SpectraATR-IR Spectra — Bio-Rad Laboratories, Inc.FTIR SpectraRaman Spectra — Bio-Rad LaboratoriesUV-VIS Spectra
Literature & Patent References
DOI 10.1021/acs.jmedchem.2c01827Fragment-to-Lead Medicinal Chemistry Publications in 2021.PMID 36622056Fragment-to-Lead Medicinal Chemistry Publications in 2021.DOI 10.1021/acs.jmedchem.1c00135Revisiting Pyrazolo[3,4-<i>d</i>]pyrimidine Nucleosides as Anti-<i>Trypanosoma cruzi</i> and Antileishmanial Agents.DOI 10.1021/acs.jmedchem.1c00720Design and Synthesis of Pyrrolo[2,3-<i>d</i>]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate.PMID 33784107Revisiting Pyrazolo[3,4-<i>d</i>]pyrimidine Nucleosides as Anti-<i>Trypanosoma cruzi</i> and Antileishmanial Agents.PMID 34184879Design and Synthesis of Pyrrolo[2,3-<i>d</i>]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate.DOI 10.1016/j.bmc.2007.03.010The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.PMID 17379526The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors.

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

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Non-public related references

6-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amineCAS 5444-29-1
4-Aminothieno(2,3-d)pyrimidineCAS 14080-56-9
1H-Pyrazolo[3,4-C]pyridine-5-carbonitrileCAS 633328-50-4
1H-pyrrolo(2,3-b)pyridin-4-amineCAS 74420-00-1
1,4,5,6-Tetrahydrocyclopenta[c]pyrazoleCAS 2214-03-1

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

CAS 5444-29-16-(Methylthio)-1H-pyrazolo[3,4-d]pyrimidin-4-amineCAS 5399-92-84-Chloro-1H-pyrazolo[3,4-d]pyrimidineCAS 16617-46-25-Amino-4-cyanopyrazoleCAS 73-24-5AdenineCAS 1002310-00-0Tert-butyl 1-(2-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethylcarbamateCAS 1005174-17-3(E)-3-(2-Propyl-6-(trifluoromethyl)pyridin-3-yl)acrylic acidCAS 1018125-49-92-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acidCAS 1018128-07-8Isopropyl 4-chloro-2-methylquinoline-6-carboxylateCAS 1018142-22-76-cyclopropyl-1-(2,2-difluoroethyl)-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acidCAS 1018144-00-72-(3-Cyclopropyl-6-isopropyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid

RFQ questions for CAS 2380-63-4

What are the key identifiers for 1H-Pyrazolo[3,4-d]pyrimidin-4-amine (CAS 2380-63-4)?

1H-Pyrazolo[3,4-d]pyrimidin-4-amine is identified by CAS 2380-63-4, with molecular formula C5H5N5, molecular weight 135.13, InChIKey LHCPRYRLDOSKHK-UHFFFAOYSA-N.

Does CAS 2380-63-4 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Leucine-rich repeat serine/threonine-protein kinase 2, Xanthine dehydrogenase/oxidase. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 2380-63-4?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for 1H-Pyrazolo[3,4-d]pyrimidin-4-amine?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 2380-63-4 available for quotation?

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