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Home/Compounds/CAS 24305-27-9
Formula C16H22N6O4MW 362.38Research-use catalog entryCOA/SDS by request

Protirelin

CAS Number: 24305-27-9

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Loading RDKit molecule structure...
InChIKey: XNSAINXGIQZQOO-SRVKXCTJSA-NC16H22N6O4 | MW 362.38

Chemical Absolute Identifiers

CAS Number

24305-27-9

PubChem CID

638678

Molecular Formula

C16H22N6O4

Molecular Weight

362.38 g/mol

Exact Mass

362.170253

InChIKey

XNSAINXGIQZQOO-SRVKXCTJSA-N

IUPAC Name

(2S)-N-[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

SMILES String

C1C[C@H](N(C1)C(=O)[C@H](CC2=CN=CN2)NC(=O)[C@@H]3CCC(=O)N3)C(=O)N

Physical Properties

No physical property values available.

Properties are provided as catalog reference data and may be confirmed through supplier documentation when required.

Catalog Facts

Structural features

Protirelin (CAS 24305-27-9) is listed in the Advanced Chemicals portfolio, with molecular formula C16H22N6O4 and molecular weight 362. 38 g/mol.

Sourcing context

Catalog reference for RFQ preparation, supplier confirmation, and research chemical sourcing review.

Research use context

Intended for research building-block and synthetic chemistry workflows; structure-derived tags include nitrogen-containing heterocycle.

Documentation needs

COA/SDS status, availability, lead time, pack size, and shipment documentation can be confirmed during quotation.

Applications & Classification

Natural Product ResearchSynthetic ChemistryResearch intermediateCustom synthesis building blockResearch chemical sourcingCustom synthesis and catalog availability reviewCOA, SDS, pricing, and fulfillment workflow
Biological target reference

ChEMBL reports experimental activity evidence for: Thyrotropin-releasing hormone receptor (Mus musculus) — 13 assays; Thyrotropin-releasing hormone receptor 2 (Mus musculus) — 5 assays; Thyrotropin-releasing hormone receptor 2 (Rattus norvegicus) — 5 assays; Thyrotropin-releasing hormone receptor (Rattus norvegicus) — 3 assays; Thyrotropin-releasing hormone receptor (Homo sapiens) — 2 assays. These records describe research assays and do not establish therapeutic efficacy or clinical use.

Thyrotropin-releasing hormone receptor

Mus musculus · SINGLE PROTEIN · 13 qualifying assays · 4 documents · best pChEMBL 9.31

Experimental evidence source: ChEMBL

Thyrotropin-releasing hormone receptor 2

Mus musculus · SINGLE PROTEIN · 5 qualifying assays · 2 documents · best pChEMBL 9.3

Experimental evidence source: ChEMBL

Thyrotropin-releasing hormone receptor 2

Rattus norvegicus · SINGLE PROTEIN · 5 qualifying assays · 3 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Thyrotropin-releasing hormone receptor

Rattus norvegicus · SINGLE PROTEIN · 3 qualifying assays · 2 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Thyrotropin-releasing hormone receptor

Homo sapiens · SINGLE PROTEIN · 2 qualifying assays · 1 documents · best pChEMBL 8.52

Experimental evidence source: ChEMBL

Safety & Handling

Safety and handling reference content is available through documentation requests.

For supplier-issued SDS, request documentation before handling, storage, shipment, or procurement decisions.

Preliminary Safety Reference

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Safety Reference / SDS Request

Names & Synonyms / External Identifiers

Chemical Name

Protirelin

Names & Synonyms

ThyroliberinLopremoneSynthetic TRHRifathyroinThypinone
Show all synonyms
Thyrotropin-releasing factorTSH-releasing factorProtirelineThyrotropic-releasing factor5-Oxo-L-prolyl-L-histidyl-L-prolinamideProtirelinumTHYREL TRHSynthetic tsh-releasing factorRelefact TRHAbbott 38579Protirelin, syntheticProtirelina5-oxo-pro-his-pro-nh2L-Pyroglutamyl-L-histidyl-L-prolineamideProtireline [INN-French]
External Identifiers
EC NUMBER: 246-143-4DSSTOX SUBSTANCE ID: DTXSID0023533CHEMBL ID: CHEMBL1472CHEBI ID: CHEBI:35940UNII: 5Y5F15120WDRUGBANK ID: DB09421HMDB ID: HMDB0060080KEGG ID: C03958KEGG ID: D00176METABOLOMICS WORKBENCH ID: 49932NCI THESAURUS CODE: C66495RXCUI: 10580WIKIDATA ID: Q12910980
Experimental Spectrum References
1D NMR Spectra
Literature & Patent References
DOI 10.1016/j.ejmech.2024.116338Structure-based discovery of potent myosin inhibitors to guide antiparasite drug development.DOI 10.6019/CHEMBL5442175EUbOPEN Chemogenomics Library - PDSP Secondary BindingDOI 10.6019/CHEMBL5442219EUbOPEN Chemogenomics Library - PDSP Primary BindingDOI 10.6019/CHEMBL5665443Enzyme Inhibitor Single Concentration assay results for EUbOPEN Chemogenomics LibraryPMID 38522112Structure-based discovery of potent myosin inhibitors to guide antiparasite drug development.DOI 10.6019/CHEMBL5209801GPCR results for EUbOPEN Chemogenomics Library 3DOI 10.6019/CHEMBL4689842EUbOPEN Chemogenomics Library wave 1DOI 10.1101/2020.04.03.023846In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication

Documentation & Compliance Facts

Compliance Facts

Shipment review: Required

Documentation available by request

Certificate of Analysis (COA): By request

Supplier Safety Data Sheet (SDS): By request

Purity and pack size confirmation: By request

Availability and lead time review: Confirmed by RFQ

Shipment documentation review: By request

For supplier-issued documentation by request, use the RFQ actions on this page.Review preliminary safety reference

What happens after RFQ

  1. 1We review the CAS identity, quantity, and documentation request.
  2. 2We check sourcing options, supplier availability, COA/SDS, purity, pack size, and lead time.
  3. 3We review destination and shipment documentation needs when applicable.
  4. 4We follow up with a quotation or clarification request.

Text Reference Cues

Additional text reference cues are not available for this catalog entry.

Non-public references are shown as text only and do not imply equivalence, availability, or shared use.

Catalog navigation

Related Catalog Entries

Other public CAS pages in this catalog. These links support navigation across additional intermediates and do not imply equivalence, availability, or shared use.

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RFQ questions for CAS 24305-27-9

What are the key identifiers for Protirelin (CAS 24305-27-9)?

Protirelin is identified by CAS 24305-27-9, with molecular formula C16H22N6O4, molecular weight 362.38, InChIKey XNSAINXGIQZQOO-SRVKXCTJSA-N.

Does CAS 24305-27-9 have reported biological target evidence?

ChEMBL contains qualifying experimental assay evidence associated with Thyrotropin-releasing hormone receptor, Thyrotropin-releasing hormone receptor 2, Thyrotropin-releasing hormone receptor 2, Thyrotropin-releasing hormone receptor, Thyrotropin-releasing hormone receptor. These records do not establish therapeutic efficacy or clinical use.

Can I request a COA for CAS 24305-27-9?

Yes. Submit an RFQ and specify COA requirements. Lot-specific COA depends on supplier confirmation.

Can I request supplier SDS for Protirelin?

Yes. Supplier SDS can be requested through the RFQ workflow before handling, storage, shipment, or procurement decisions.

Is CAS 24305-27-9 available for quotation?

Availability, pack size, lead time, and pricing are confirmed through RFQ.

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